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EIF4E (eukaryotic translation initiation factor 4E)

Gene

1977

Eukaryotic translation initiation factor 4E

EIF4E

AUTS19, CBP, EIF4E1, EIF4EL1, EIF4F, eIF-4E

4q23

The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5` end of messenger RNAs. The encoded protein aids in translation initiation by recruit

Show/Hide all(607)

miRTarBase ID	miRNA	Experiments	Reference
MIRT001469	hsa-miR-16-5p	pSILAC	18668040
MIRT005479	hsa-miR-141-3p	Luciferase reporter assay, Northern blot, qRT-PCR, Western blot	21238947
MIRT005878	hsa-miR-145-5p	Luciferase reporter assay, qRT-PCR, Western blot	21092188
MIRT022728	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT023809	hsa-miR-1-3p	Proteomics	18668040
MIRT025789	hsa-miR-7-5p	Microarray	17612493
MIRT001469	hsa-miR-16-5p	Proteomics;Other	18668040
MIRT039192	hsa-miR-769-5p	CLASH	23622248
MIRT037944	hsa-miR-505-5p	CLASH	23622248
MIRT053773	hsa-miR-497-5p	In situ hybridization, Luciferase reporter assay, qRT-PCR, Western blot	24845562
MIRT053773	hsa-miR-497-5p	In situ hybridization, Luciferase reporter assay, qRT-PCR, Western blot	24845562
MIRT624061	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT624060	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT658781	hsa-miR-96-3p	HITS-CLIP	23824327
MIRT624062	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT632961	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT632960	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT632959	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT632958	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT632957	hsa-miR-4319	HITS-CLIP	23824327
MIRT632956	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT632955	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT632954	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT632953	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT632952	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT632951	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT624059	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT658780	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT632950	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT624058	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT624057	hsa-miR-6131	HITS-CLIP	23824327
MIRT632949	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT624054	hsa-miR-548s	HITS-CLIP	23824327
MIRT624053	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT624052	hsa-miR-588	HITS-CLIP	23824327
MIRT624051	hsa-miR-4435	HITS-CLIP	23824327
MIRT624050	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT624049	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT624048	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT624062	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT624061	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT624060	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT632961	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT632960	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT632959	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT632958	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT632957	hsa-miR-4319	HITS-CLIP	23824327
MIRT632956	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT632955	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT632954	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT632953	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT632952	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT632951	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT624059	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT632950	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT624058	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT624057	hsa-miR-6131	HITS-CLIP	23824327
MIRT632949	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT624054	hsa-miR-548s	HITS-CLIP	23824327
MIRT624053	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT624052	hsa-miR-588	HITS-CLIP	23824327
MIRT624051	hsa-miR-4435	HITS-CLIP	23824327
MIRT624050	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT624049	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT624048	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT624062	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT624061	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT624060	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT624059	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT624058	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT624057	hsa-miR-6131	HITS-CLIP	23824327
MIRT624056	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT624055	hsa-miR-7641	HITS-CLIP	23824327
MIRT624054	hsa-miR-548s	HITS-CLIP	23824327
MIRT624053	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT624052	hsa-miR-588	HITS-CLIP	23824327
MIRT624051	hsa-miR-4435	HITS-CLIP	23824327
MIRT624050	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT624049	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT624048	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT562401	hsa-miR-4760-3p	PAR-CLIP	20371350
MIRT562402	hsa-miR-4302	PAR-CLIP	20371350
MIRT562400	hsa-miR-4289	PAR-CLIP	20371350
MIRT025789	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT562399	hsa-miR-6077	PAR-CLIP	20371350
MIRT562398	hsa-miR-3190-3p	PAR-CLIP	20371350
MIRT562397	hsa-miR-3688-5p	PAR-CLIP	20371350
MIRT562396	hsa-miR-891a-3p	PAR-CLIP	20371350
MIRT562395	hsa-miR-644a	PAR-CLIP	20371350
MIRT562393	hsa-miR-6833-5p	PAR-CLIP	20371350
MIRT562394	hsa-miR-4752	PAR-CLIP	20371350
MIRT523935	hsa-miR-6835-3p	PAR-CLIP	23446348
MIRT523934	hsa-miR-4422	PAR-CLIP	23446348
MIRT523933	hsa-miR-4438	PAR-CLIP	23446348
MIRT311084	hsa-miR-6504-3p	PAR-CLIP	23446348
MIRT523932	hsa-miR-619-5p	PAR-CLIP	23446348
MIRT523930	hsa-miR-6506-5p	PAR-CLIP	23446348
MIRT523931	hsa-miR-5095	PAR-CLIP	23446348
MIRT523929	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT523928	hsa-miR-5089-5p	PAR-CLIP	23446348
MIRT732058	hsa-miR-34c-3p	Luciferase reporter assay, qRT-PCR, Western blot	26250586
MIRT732058	hsa-miR-34c-3p	Luciferase reporter assay, qRT-PCR, Western blot	26250586
MIRT734137	hsa-miR-613	Western blotting, Immunofluorescence, qRT-PCR	32943930
MIRT624061	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT624060	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT658781	hsa-miR-96-3p	HITS-CLIP	23824327
MIRT624062	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT632961	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT632960	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT632959	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT632958	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT632957	hsa-miR-4319	HITS-CLIP	23824327
MIRT632956	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT632955	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT632954	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT632953	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT632952	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT632951	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT624059	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT658780	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT632950	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT624058	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT624057	hsa-miR-6131	HITS-CLIP	23824327
MIRT632949	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT624054	hsa-miR-548s	HITS-CLIP	23824327
MIRT624053	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT624052	hsa-miR-588	HITS-CLIP	23824327
MIRT624051	hsa-miR-4435	HITS-CLIP	23824327
MIRT624050	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT624049	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT624048	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT624062	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT624061	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT624060	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT632961	hsa-miR-345-3p	HITS-CLIP	23824327
MIRT632960	hsa-miR-4732-3p	HITS-CLIP	23824327
MIRT632959	hsa-miR-125a-5p	HITS-CLIP	23824327
MIRT632958	hsa-miR-125b-5p	HITS-CLIP	23824327
MIRT632957	hsa-miR-4319	HITS-CLIP	23824327
MIRT632956	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT632955	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT632954	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT632953	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT632952	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT632951	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT624059	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT632950	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT624058	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT624057	hsa-miR-6131	HITS-CLIP	23824327
MIRT632949	hsa-miR-670-5p	HITS-CLIP	23824327
MIRT624054	hsa-miR-548s	HITS-CLIP	23824327
MIRT624053	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT624052	hsa-miR-588	HITS-CLIP	23824327
MIRT624051	hsa-miR-4435	HITS-CLIP	23824327
MIRT624050	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT624049	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT624048	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT624062	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT624061	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT624060	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT624059	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT624058	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT624057	hsa-miR-6131	HITS-CLIP	23824327
MIRT624056	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT624055	hsa-miR-7641	HITS-CLIP	23824327
MIRT624054	hsa-miR-548s	HITS-CLIP	23824327
MIRT624053	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT624052	hsa-miR-588	HITS-CLIP	23824327
MIRT624051	hsa-miR-4435	HITS-CLIP	23824327
MIRT624050	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT624049	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT624048	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT562401	hsa-miR-4760-3p	PAR-CLIP	20371350
MIRT562402	hsa-miR-4302	PAR-CLIP	20371350
MIRT562400	hsa-miR-4289	PAR-CLIP	20371350
MIRT025789	hsa-miR-7-5p	PAR-CLIP	20371350
MIRT562399	hsa-miR-6077	PAR-CLIP	20371350
MIRT562398	hsa-miR-3190-3p	PAR-CLIP	20371350
MIRT562397	hsa-miR-3688-5p	PAR-CLIP	20371350
MIRT562396	hsa-miR-891a-3p	PAR-CLIP	20371350
MIRT562395	hsa-miR-644a	PAR-CLIP	20371350
MIRT562393	hsa-miR-6833-5p	PAR-CLIP	20371350
MIRT562394	hsa-miR-4752	PAR-CLIP	20371350
MIRT523935	hsa-miR-6835-3p	PAR-CLIP	23446348
MIRT523934	hsa-miR-4422	PAR-CLIP	23446348
MIRT523933	hsa-miR-4438	PAR-CLIP	23446348
MIRT311084	hsa-miR-6504-3p	PAR-CLIP	23446348
MIRT523932	hsa-miR-619-5p	PAR-CLIP	23446348
MIRT523930	hsa-miR-6506-5p	PAR-CLIP	23446348
MIRT523931	hsa-miR-5095	PAR-CLIP	23446348
MIRT523929	hsa-miR-7151-3p	PAR-CLIP	23446348
MIRT523928	hsa-miR-5089-5p	PAR-CLIP	23446348
MIRT958118	hsa-miR-1288	CLIP-seq
MIRT958119	hsa-miR-200b	CLIP-seq
MIRT958120	hsa-miR-200c	CLIP-seq
MIRT958121	hsa-miR-23a	CLIP-seq
MIRT958122	hsa-miR-23b	CLIP-seq
MIRT958123	hsa-miR-23c	CLIP-seq
MIRT958124	hsa-miR-3140-3p	CLIP-seq
MIRT958125	hsa-miR-3199	CLIP-seq
MIRT958126	hsa-miR-429	CLIP-seq
MIRT958127	hsa-miR-4328	CLIP-seq
MIRT958128	hsa-miR-4474-3p	CLIP-seq
MIRT958129	hsa-miR-4517	CLIP-seq
MIRT958130	hsa-miR-4699-3p	CLIP-seq
MIRT958131	hsa-miR-4717-3p	CLIP-seq
MIRT958132	hsa-miR-4724-5p	CLIP-seq
MIRT958133	hsa-miR-4790-3p	CLIP-seq
MIRT958134	hsa-miR-4802-3p	CLIP-seq
MIRT958135	hsa-miR-582-5p	CLIP-seq
MIRT958136	hsa-miR-7	CLIP-seq
MIRT958137	hsa-miR-889	CLIP-seq
MIRT958138	hsa-miR-1246	CLIP-seq
MIRT958139	hsa-miR-1269	CLIP-seq
MIRT958140	hsa-miR-1269b	CLIP-seq
MIRT958141	hsa-miR-15a	CLIP-seq
MIRT958142	hsa-miR-15b	CLIP-seq
MIRT958143	hsa-miR-16	CLIP-seq
MIRT958144	hsa-miR-195	CLIP-seq
MIRT958145	hsa-miR-3120-3p	CLIP-seq
MIRT958146	hsa-miR-424	CLIP-seq
MIRT958147	hsa-miR-4272	CLIP-seq
MIRT958148	hsa-miR-4282	CLIP-seq
MIRT958149	hsa-miR-4314	CLIP-seq
MIRT958150	hsa-miR-4320	CLIP-seq
MIRT958151	hsa-miR-4450	CLIP-seq
MIRT958152	hsa-miR-4477a	CLIP-seq
MIRT958153	hsa-miR-4481	CLIP-seq
MIRT958154	hsa-miR-451b	CLIP-seq
MIRT958155	hsa-miR-4524	CLIP-seq
MIRT958156	hsa-miR-4529-3p	CLIP-seq
MIRT958157	hsa-miR-4640-5p	CLIP-seq
MIRT958158	hsa-miR-4667-5p	CLIP-seq
MIRT958159	hsa-miR-4700-5p	CLIP-seq
MIRT958160	hsa-miR-4720-3p	CLIP-seq
MIRT958161	hsa-miR-4726-5p	CLIP-seq
MIRT958162	hsa-miR-4729	CLIP-seq
MIRT958163	hsa-miR-4745-5p	CLIP-seq
MIRT958164	hsa-miR-4804-3p	CLIP-seq
MIRT958165	hsa-miR-497	CLIP-seq
MIRT958166	hsa-miR-503	CLIP-seq
MIRT958167	hsa-miR-545	CLIP-seq
MIRT958168	hsa-miR-548c-3p	CLIP-seq
MIRT958169	hsa-miR-637	CLIP-seq
MIRT958170	hsa-miR-646	CLIP-seq
MIRT958171	hsa-miR-873	CLIP-seq
MIRT958172	hsa-miR-1	CLIP-seq
MIRT958173	hsa-miR-1258	CLIP-seq
MIRT958174	hsa-miR-1297	CLIP-seq
MIRT958141	hsa-miR-15a	CLIP-seq
MIRT958142	hsa-miR-15b	CLIP-seq
MIRT958143	hsa-miR-16	CLIP-seq
MIRT958144	hsa-miR-195	CLIP-seq
MIRT958175	hsa-miR-203	CLIP-seq
MIRT958176	hsa-miR-206	CLIP-seq
MIRT958177	hsa-miR-224	CLIP-seq
MIRT958121	hsa-miR-23a	CLIP-seq
MIRT958122	hsa-miR-23b	CLIP-seq
MIRT958123	hsa-miR-23c	CLIP-seq
MIRT958178	hsa-miR-26a	CLIP-seq
MIRT958179	hsa-miR-26b	CLIP-seq
MIRT958180	hsa-miR-297	CLIP-seq
MIRT958145	hsa-miR-3120-3p	CLIP-seq
MIRT958181	hsa-miR-3163	CLIP-seq
MIRT958182	hsa-miR-3192	CLIP-seq
MIRT958183	hsa-miR-340	CLIP-seq
MIRT958184	hsa-miR-34b	CLIP-seq
MIRT958185	hsa-miR-3607-3p	CLIP-seq
MIRT958186	hsa-miR-3617	CLIP-seq
MIRT958187	hsa-miR-3674	CLIP-seq
MIRT958188	hsa-miR-374a	CLIP-seq
MIRT958189	hsa-miR-374b	CLIP-seq
MIRT958190	hsa-miR-376c	CLIP-seq
MIRT958191	hsa-miR-377	CLIP-seq
MIRT958192	hsa-miR-380	CLIP-seq
MIRT958193	hsa-miR-382	CLIP-seq
MIRT958146	hsa-miR-424	CLIP-seq
MIRT958194	hsa-miR-4261	CLIP-seq
MIRT958195	hsa-miR-4307	CLIP-seq
MIRT958196	hsa-miR-4420	CLIP-seq
MIRT958197	hsa-miR-4465	CLIP-seq
MIRT958198	hsa-miR-4480	CLIP-seq
MIRT958199	hsa-miR-4495	CLIP-seq
MIRT958200	hsa-miR-4496	CLIP-seq
MIRT958154	hsa-miR-451b	CLIP-seq
MIRT958155	hsa-miR-4524	CLIP-seq
MIRT958201	hsa-miR-4539	CLIP-seq
MIRT958202	hsa-miR-4668-3p	CLIP-seq
MIRT958131	hsa-miR-4717-3p	CLIP-seq
MIRT958132	hsa-miR-4724-5p	CLIP-seq
MIRT958203	hsa-miR-4728-3p	CLIP-seq
MIRT958204	hsa-miR-4742-3p	CLIP-seq
MIRT958205	hsa-miR-4793-3p	CLIP-seq
MIRT958134	hsa-miR-4802-3p	CLIP-seq
MIRT958165	hsa-miR-497	CLIP-seq
MIRT958166	hsa-miR-503	CLIP-seq
MIRT958206	hsa-miR-508-5p	CLIP-seq
MIRT958207	hsa-miR-513a-3p	CLIP-seq
MIRT958167	hsa-miR-545	CLIP-seq
MIRT958208	hsa-miR-548a-5p	CLIP-seq
MIRT958209	hsa-miR-548ab	CLIP-seq
MIRT958210	hsa-miR-548ak	CLIP-seq
MIRT958211	hsa-miR-548b-5p	CLIP-seq
MIRT958212	hsa-miR-548c-5p	CLIP-seq
MIRT958213	hsa-miR-548d-5p	CLIP-seq
MIRT958214	hsa-miR-548h	CLIP-seq
MIRT958215	hsa-miR-548i	CLIP-seq
MIRT958216	hsa-miR-548j	CLIP-seq
MIRT958217	hsa-miR-548k	CLIP-seq
MIRT958218	hsa-miR-548l	CLIP-seq
MIRT958219	hsa-miR-548p	CLIP-seq
MIRT958220	hsa-miR-548w	CLIP-seq
MIRT958221	hsa-miR-548y	CLIP-seq
MIRT958222	hsa-miR-550a	CLIP-seq
MIRT958223	hsa-miR-559	CLIP-seq
MIRT958224	hsa-miR-567	CLIP-seq
MIRT958225	hsa-miR-641	CLIP-seq
MIRT958170	hsa-miR-646	CLIP-seq
MIRT958226	hsa-miR-651	CLIP-seq
MIRT958227	hsa-miR-656	CLIP-seq
MIRT958228	hsa-miR-661	CLIP-seq
MIRT958136	hsa-miR-7	CLIP-seq
MIRT958229	hsa-miR-766	CLIP-seq
MIRT958121	hsa-miR-23a	CLIP-seq
MIRT958122	hsa-miR-23b	CLIP-seq
MIRT958123	hsa-miR-23c	CLIP-seq
MIRT958131	hsa-miR-4717-3p	CLIP-seq
MIRT958203	hsa-miR-4728-3p	CLIP-seq
MIRT958134	hsa-miR-4802-3p	CLIP-seq
MIRT958136	hsa-miR-7	CLIP-seq
MIRT1983791	hsa-miR-1279	CLIP-seq
MIRT958167	hsa-miR-545	CLIP-seq
MIRT958187	hsa-miR-3674	CLIP-seq
MIRT958167	hsa-miR-545	CLIP-seq
MIRT958167	hsa-miR-545	CLIP-seq
MIRT2219073	hsa-miR-1208	CLIP-seq
MIRT2219074	hsa-miR-1224-3p	CLIP-seq
MIRT2219075	hsa-miR-1260	CLIP-seq
MIRT2219076	hsa-miR-1260b	CLIP-seq
MIRT2219077	hsa-miR-1280	CLIP-seq
MIRT958141	hsa-miR-15a	CLIP-seq
MIRT958142	hsa-miR-15b	CLIP-seq
MIRT958143	hsa-miR-16	CLIP-seq
MIRT958144	hsa-miR-195	CLIP-seq
MIRT958145	hsa-miR-3120-3p	CLIP-seq
MIRT958187	hsa-miR-3674	CLIP-seq
MIRT958146	hsa-miR-424	CLIP-seq
MIRT958196	hsa-miR-4420	CLIP-seq
MIRT958154	hsa-miR-451b	CLIP-seq
MIRT958155	hsa-miR-4524	CLIP-seq
MIRT958202	hsa-miR-4668-3p	CLIP-seq
MIRT958165	hsa-miR-497	CLIP-seq
MIRT958166	hsa-miR-503	CLIP-seq
MIRT958167	hsa-miR-545	CLIP-seq
MIRT958135	hsa-miR-582-5p	CLIP-seq
MIRT2219078	hsa-miR-587	CLIP-seq
MIRT958170	hsa-miR-646	CLIP-seq
MIRT958182	hsa-miR-3192	CLIP-seq
MIRT2387321	hsa-miR-4252	CLIP-seq
MIRT958205	hsa-miR-4793-3p	CLIP-seq
MIRT958206	hsa-miR-508-5p	CLIP-seq
MIRT958167	hsa-miR-545	CLIP-seq
MIRT958228	hsa-miR-661	CLIP-seq
MIRT958229	hsa-miR-766	CLIP-seq
MIRT2465200	hsa-miR-3613-3p	CLIP-seq
MIRT2465201	hsa-miR-3622b-5p	CLIP-seq
MIRT2465202	hsa-miR-4253	CLIP-seq
MIRT2465203	hsa-miR-4684-5p	CLIP-seq
MIRT958168	hsa-miR-548c-3p	CLIP-seq
MIRT958172	hsa-miR-1	CLIP-seq
MIRT2522327	hsa-miR-105	CLIP-seq
MIRT2219073	hsa-miR-1208	CLIP-seq
MIRT958173	hsa-miR-1258	CLIP-seq
MIRT2522328	hsa-miR-1272	CLIP-seq
MIRT2522329	hsa-miR-1273e	CLIP-seq
MIRT2522330	hsa-miR-1283	CLIP-seq
MIRT958118	hsa-miR-1288	CLIP-seq
MIRT958174	hsa-miR-1297	CLIP-seq
MIRT2522331	hsa-miR-1305	CLIP-seq
MIRT2522332	hsa-miR-1322	CLIP-seq
MIRT2522333	hsa-miR-1343	CLIP-seq
MIRT2522334	hsa-miR-150	CLIP-seq
MIRT2522335	hsa-miR-155	CLIP-seq
MIRT958141	hsa-miR-15a	CLIP-seq
MIRT958142	hsa-miR-15b	CLIP-seq
MIRT958143	hsa-miR-16	CLIP-seq
MIRT958144	hsa-miR-195	CLIP-seq
MIRT2522336	hsa-miR-197	CLIP-seq
MIRT2522337	hsa-miR-205	CLIP-seq
MIRT2522338	hsa-miR-2054	CLIP-seq
MIRT958176	hsa-miR-206	CLIP-seq
MIRT958178	hsa-miR-26a	CLIP-seq
MIRT958179	hsa-miR-26b	CLIP-seq
MIRT2522339	hsa-miR-302f	CLIP-seq
MIRT2522340	hsa-miR-3074-5p	CLIP-seq
MIRT2522341	hsa-miR-3117-5p	CLIP-seq
MIRT958145	hsa-miR-3120-3p	CLIP-seq
MIRT958124	hsa-miR-3140-3p	CLIP-seq
MIRT2522342	hsa-miR-3143	CLIP-seq
MIRT2522343	hsa-miR-3162-3p	CLIP-seq
MIRT958181	hsa-miR-3163	CLIP-seq
MIRT2522344	hsa-miR-3188	CLIP-seq
MIRT958182	hsa-miR-3192	CLIP-seq
MIRT958125	hsa-miR-3199	CLIP-seq
MIRT2522345	hsa-miR-3200-5p	CLIP-seq
MIRT2522346	hsa-miR-323-3p	CLIP-seq
MIRT2522347	hsa-miR-330-3p	CLIP-seq
MIRT958184	hsa-miR-34b	CLIP-seq
MIRT958185	hsa-miR-3607-3p	CLIP-seq
MIRT2465200	hsa-miR-3613-3p	CLIP-seq
MIRT2465201	hsa-miR-3622b-5p	CLIP-seq
MIRT2522348	hsa-miR-3647-3p	CLIP-seq
MIRT2522349	hsa-miR-3662	CLIP-seq
MIRT2522350	hsa-miR-3672	CLIP-seq
MIRT958187	hsa-miR-3674	CLIP-seq
MIRT2522351	hsa-miR-3688-3p	CLIP-seq
MIRT2522352	hsa-miR-3690	CLIP-seq
MIRT958188	hsa-miR-374a	CLIP-seq
MIRT958189	hsa-miR-374b	CLIP-seq
MIRT2522353	hsa-miR-374c	CLIP-seq
MIRT958190	hsa-miR-376c	CLIP-seq
MIRT958191	hsa-miR-377	CLIP-seq
MIRT958192	hsa-miR-380	CLIP-seq
MIRT2522354	hsa-miR-412	CLIP-seq
MIRT958146	hsa-miR-424	CLIP-seq
MIRT2387321	hsa-miR-4252	CLIP-seq
MIRT2465202	hsa-miR-4253	CLIP-seq
MIRT2522355	hsa-miR-4254	CLIP-seq
MIRT958194	hsa-miR-4261	CLIP-seq
MIRT958147	hsa-miR-4272	CLIP-seq
MIRT2522356	hsa-miR-4286	CLIP-seq
MIRT2522357	hsa-miR-4291	CLIP-seq
MIRT958195	hsa-miR-4307	CLIP-seq
MIRT2522358	hsa-miR-4426	CLIP-seq
MIRT2522359	hsa-miR-4432	CLIP-seq
MIRT2522360	hsa-miR-4446-5p	CLIP-seq
MIRT958197	hsa-miR-4465	CLIP-seq
MIRT958152	hsa-miR-4477a	CLIP-seq
MIRT2522361	hsa-miR-448	CLIP-seq
MIRT958200	hsa-miR-4496	CLIP-seq
MIRT958129	hsa-miR-4517	CLIP-seq
MIRT958154	hsa-miR-451b	CLIP-seq
MIRT958155	hsa-miR-4524	CLIP-seq
MIRT2522362	hsa-miR-4647	CLIP-seq
MIRT2522363	hsa-miR-4662b	CLIP-seq
MIRT958202	hsa-miR-4668-3p	CLIP-seq
MIRT2522364	hsa-miR-4682	CLIP-seq
MIRT2465203	hsa-miR-4684-5p	CLIP-seq
MIRT2522365	hsa-miR-4694-3p	CLIP-seq
MIRT958130	hsa-miR-4699-3p	CLIP-seq
MIRT2522366	hsa-miR-4709-3p	CLIP-seq
MIRT2522367	hsa-miR-4711-3p	CLIP-seq
MIRT2522368	hsa-miR-4711-5p	CLIP-seq
MIRT2522369	hsa-miR-4712-3p	CLIP-seq
MIRT2522370	hsa-miR-4718	CLIP-seq
MIRT2522371	hsa-miR-4733-5p	CLIP-seq
MIRT2522372	hsa-miR-4753-3p	CLIP-seq
MIRT2522373	hsa-miR-4755-5p	CLIP-seq
MIRT2522374	hsa-miR-4762-5p	CLIP-seq
MIRT958133	hsa-miR-4790-3p	CLIP-seq
MIRT958205	hsa-miR-4793-3p	CLIP-seq
MIRT2522375	hsa-miR-4803	CLIP-seq
MIRT2522376	hsa-miR-486-5p	CLIP-seq
MIRT2522377	hsa-miR-496	CLIP-seq
MIRT958165	hsa-miR-497	CLIP-seq
MIRT2522378	hsa-miR-498	CLIP-seq
MIRT2522379	hsa-miR-499-5p	CLIP-seq
MIRT958166	hsa-miR-503	CLIP-seq
MIRT958206	hsa-miR-508-5p	CLIP-seq
MIRT2522380	hsa-miR-510	CLIP-seq
MIRT2522381	hsa-miR-512-5p	CLIP-seq
MIRT2522382	hsa-miR-520d-5p	CLIP-seq
MIRT2522383	hsa-miR-520g	CLIP-seq
MIRT2522384	hsa-miR-520h	CLIP-seq
MIRT2522385	hsa-miR-522	CLIP-seq
MIRT2522386	hsa-miR-524-5p	CLIP-seq
MIRT2522387	hsa-miR-543	CLIP-seq
MIRT2522388	hsa-miR-544	CLIP-seq
MIRT958167	hsa-miR-545	CLIP-seq
MIRT2522389	hsa-miR-548a-3p	CLIP-seq
MIRT958168	hsa-miR-548c-3p	CLIP-seq
MIRT2522390	hsa-miR-548e	CLIP-seq
MIRT2522391	hsa-miR-548f	CLIP-seq
MIRT2522392	hsa-miR-548g	CLIP-seq
MIRT958219	hsa-miR-548p	CLIP-seq
MIRT2522393	hsa-miR-580	CLIP-seq
MIRT2522394	hsa-miR-586	CLIP-seq
MIRT2522395	hsa-miR-607	CLIP-seq
MIRT2522396	hsa-miR-634	CLIP-seq
MIRT958170	hsa-miR-646	CLIP-seq
MIRT958226	hsa-miR-651	CLIP-seq
MIRT2522397	hsa-miR-655	CLIP-seq
MIRT958227	hsa-miR-656	CLIP-seq
MIRT2522398	hsa-miR-659	CLIP-seq
MIRT958228	hsa-miR-661	CLIP-seq
MIRT958229	hsa-miR-766	CLIP-seq
MIRT2522399	hsa-miR-802	CLIP-seq
MIRT958137	hsa-miR-889	CLIP-seq
MIRT2522400	hsa-miR-9	CLIP-seq
MIRT2522401	hsa-miR-942	CLIP-seq
MIRT2522402	hsa-miR-944	CLIP-seq
MIRT958172	hsa-miR-1	CLIP-seq
MIRT2522327	hsa-miR-105	CLIP-seq
MIRT2219073	hsa-miR-1208	CLIP-seq
MIRT958173	hsa-miR-1258	CLIP-seq
MIRT2522328	hsa-miR-1272	CLIP-seq
MIRT2522329	hsa-miR-1273e	CLIP-seq
MIRT2522330	hsa-miR-1283	CLIP-seq
MIRT958118	hsa-miR-1288	CLIP-seq
MIRT958174	hsa-miR-1297	CLIP-seq
MIRT2522331	hsa-miR-1305	CLIP-seq
MIRT2522332	hsa-miR-1322	CLIP-seq
MIRT2522334	hsa-miR-150	CLIP-seq
MIRT2522335	hsa-miR-155	CLIP-seq
MIRT958141	hsa-miR-15a	CLIP-seq
MIRT958142	hsa-miR-15b	CLIP-seq
MIRT958143	hsa-miR-16	CLIP-seq
MIRT958144	hsa-miR-195	CLIP-seq
MIRT958176	hsa-miR-206	CLIP-seq
MIRT958178	hsa-miR-26a	CLIP-seq
MIRT958179	hsa-miR-26b	CLIP-seq
MIRT2522339	hsa-miR-302f	CLIP-seq
MIRT2522341	hsa-miR-3117-5p	CLIP-seq
MIRT958145	hsa-miR-3120-3p	CLIP-seq
MIRT958124	hsa-miR-3140-3p	CLIP-seq
MIRT2522342	hsa-miR-3143	CLIP-seq
MIRT958181	hsa-miR-3163	CLIP-seq
MIRT2522344	hsa-miR-3188	CLIP-seq
MIRT958182	hsa-miR-3192	CLIP-seq
MIRT958125	hsa-miR-3199	CLIP-seq
MIRT2522345	hsa-miR-3200-5p	CLIP-seq
MIRT958184	hsa-miR-34b	CLIP-seq
MIRT958185	hsa-miR-3607-3p	CLIP-seq
MIRT2465200	hsa-miR-3613-3p	CLIP-seq
MIRT2465201	hsa-miR-3622b-5p	CLIP-seq
MIRT2522348	hsa-miR-3647-3p	CLIP-seq
MIRT2522349	hsa-miR-3662	CLIP-seq
MIRT2522350	hsa-miR-3672	CLIP-seq
MIRT958187	hsa-miR-3674	CLIP-seq
MIRT2522351	hsa-miR-3688-3p	CLIP-seq
MIRT958188	hsa-miR-374a	CLIP-seq
MIRT958189	hsa-miR-374b	CLIP-seq
MIRT958190	hsa-miR-376c	CLIP-seq
MIRT958191	hsa-miR-377	CLIP-seq
MIRT958192	hsa-miR-380	CLIP-seq
MIRT958146	hsa-miR-424	CLIP-seq
MIRT2387321	hsa-miR-4252	CLIP-seq
MIRT2465202	hsa-miR-4253	CLIP-seq
MIRT958194	hsa-miR-4261	CLIP-seq
MIRT2522357	hsa-miR-4291	CLIP-seq
MIRT958195	hsa-miR-4307	CLIP-seq
MIRT2522358	hsa-miR-4426	CLIP-seq
MIRT958197	hsa-miR-4465	CLIP-seq
MIRT958152	hsa-miR-4477a	CLIP-seq
MIRT2522361	hsa-miR-448	CLIP-seq
MIRT958200	hsa-miR-4496	CLIP-seq
MIRT958154	hsa-miR-451b	CLIP-seq
MIRT958155	hsa-miR-4524	CLIP-seq
MIRT2522362	hsa-miR-4647	CLIP-seq
MIRT2522363	hsa-miR-4662b	CLIP-seq
MIRT958202	hsa-miR-4668-3p	CLIP-seq
MIRT2522364	hsa-miR-4682	CLIP-seq
MIRT2465203	hsa-miR-4684-5p	CLIP-seq
MIRT2522365	hsa-miR-4694-3p	CLIP-seq
MIRT2522366	hsa-miR-4709-3p	CLIP-seq
MIRT2522367	hsa-miR-4711-3p	CLIP-seq
MIRT2522368	hsa-miR-4711-5p	CLIP-seq
MIRT2522369	hsa-miR-4712-3p	CLIP-seq
MIRT2522370	hsa-miR-4718	CLIP-seq
MIRT2522371	hsa-miR-4733-5p	CLIP-seq
MIRT2522372	hsa-miR-4753-3p	CLIP-seq
MIRT2522374	hsa-miR-4762-5p	CLIP-seq
MIRT958205	hsa-miR-4793-3p	CLIP-seq
MIRT2522375	hsa-miR-4803	CLIP-seq
MIRT2522377	hsa-miR-496	CLIP-seq
MIRT958165	hsa-miR-497	CLIP-seq
MIRT2522378	hsa-miR-498	CLIP-seq
MIRT958166	hsa-miR-503	CLIP-seq
MIRT958206	hsa-miR-508-5p	CLIP-seq
MIRT2522380	hsa-miR-510	CLIP-seq
MIRT2522381	hsa-miR-512-5p	CLIP-seq
MIRT2522382	hsa-miR-520d-5p	CLIP-seq
MIRT2522385	hsa-miR-522	CLIP-seq
MIRT2522386	hsa-miR-524-5p	CLIP-seq
MIRT2522387	hsa-miR-543	CLIP-seq
MIRT2522388	hsa-miR-544	CLIP-seq
MIRT958167	hsa-miR-545	CLIP-seq
MIRT2522389	hsa-miR-548a-3p	CLIP-seq
MIRT958168	hsa-miR-548c-3p	CLIP-seq
MIRT2522390	hsa-miR-548e	CLIP-seq
MIRT2522391	hsa-miR-548f	CLIP-seq
MIRT2522392	hsa-miR-548g	CLIP-seq
MIRT958219	hsa-miR-548p	CLIP-seq
MIRT2522393	hsa-miR-580	CLIP-seq
MIRT2522394	hsa-miR-586	CLIP-seq
MIRT2522395	hsa-miR-607	CLIP-seq
MIRT2522396	hsa-miR-634	CLIP-seq
MIRT958170	hsa-miR-646	CLIP-seq
MIRT958226	hsa-miR-651	CLIP-seq
MIRT958227	hsa-miR-656	CLIP-seq
MIRT2522398	hsa-miR-659	CLIP-seq
MIRT958228	hsa-miR-661	CLIP-seq
MIRT958229	hsa-miR-766	CLIP-seq
MIRT2522399	hsa-miR-802	CLIP-seq
MIRT2522400	hsa-miR-9	CLIP-seq
MIRT2522401	hsa-miR-942	CLIP-seq
MIRT2522402	hsa-miR-944	CLIP-seq

Show/Hide all(42)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000082	Process	G1/S transition of mitotic cell cycle	IMP	14673156
GO:0000339	Function	RNA cap binding	TAS	3469651
GO:0000340	Function	RNA 7-methylguanosine cap binding	IBA	21873635
GO:0000340	Function	RNA 7-methylguanosine cap binding	IDA	19750007
GO:0000932	Component	P-body	IDA	16157702, 20616046, 24335285
GO:0001662	Process	Behavioral fear response	IEA
GO:0003723	Function	RNA binding	HDA	22681889
GO:0003743	Function	Translation initiation factor activity	IBA	21873635
GO:0003743	Function	Translation initiation factor activity	IDA	22578813
GO:0003743	Function	Translation initiation factor activity	ISS
GO:0005515	Function	Protein binding	IPI	7651417, 10772338, 10856257, 15153109, 15247416, 15361857, 16157702, 16189514, 16271312, 16467844, 16504179, 16699599, 16739988, 18955708, 19060904, 19262567, 19834456, 20212144, 20224576, 20430826, 20616046, 20880835, 20927323, 21191102, 22678294, 23665581, 23788676, 23991149, 2420
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IDA	19393246, 23814182
GO:0005829	Component	Cytosol	IDA	19750007
GO:0005829	Component	Cytosol	TAS
GO:0005845	Component	MRNA cap binding complex	IDA	16271312
GO:0006405	Process	RNA export from nucleus	TAS
GO:0006406	Process	MRNA export from nucleus	TAS
GO:0006413	Process	Translational initiation	TAS
GO:0006417	Process	Regulation of translation	IDA	22578813
GO:0010494	Component	Cytoplasmic stress granule	IDA	21883093
GO:0010507	Process	Negative regulation of autophagy	IMP	18426977
GO:0016032	Process	Viral process	IEA
GO:0016281	Component	Eukaryotic translation initiation factor 4F complex	IBA	21873635
GO:0016281	Component	Eukaryotic translation initiation factor 4F complex	IDA	22578813
GO:0016442	Component	RISC complex	IDA	20616046
GO:0017148	Process	Negative regulation of translation	IEA
GO:0019827	Process	Stem cell population maintenance	IEA
GO:0019899	Function	Enzyme binding	IDA	23814182
GO:0030324	Process	Lung development	IEA
GO:0031370	Function	Eukaryotic initiation factor 4G binding	IDA	18337562, 23814182
GO:0033391	Component	Chromatoid body	IEA
GO:0036464	Component	Cytoplasmic ribonucleoprotein granule	IDA
GO:0045665	Process	Negative regulation of neuron differentiation	IEA
GO:0045931	Process	Positive regulation of mitotic cell cycle	IMP	14673156
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	23814182
GO:0070062	Component	Extracellular exosome	HDA	20458337
GO:0070491	Function	Repressing transcription factor binding	IDA	23814182
GO:0071549	Process	Cellular response to dexamethasone stimulus	IEA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0099524	Component	Postsynaptic cytosol	IEA
GO:0099578	Process	Regulation of translation at postsynapse, modulating synaptic transmission	IEA

MIM	HGNC	e!Ensembl
133440	3287	ENSG00000151247

Protein

UniProt ID

P06730

Protein name

Eukaryotic translation initiation factor 4E (eIF-4E) (eIF4E) (eIF-4F 25 kDa subunit) (mRNA cap-binding protein)

Protein function

Acts in the cytoplasm to initiate and regulate protein synthesis and is required in the nucleus for export of a subset of mRNAs from the nucleus to the cytoplasm which promotes processes such as RNA capping, processing and splicing (PubMed:11606

PDB

1IPB , 1IPC , 1WKW , 2GPQ , 2V8W , 2V8X , 2V8Y , 2W97 , 3AM7 , 3TF2 , 3U7X , 4AZA , 4BEA , 4DT6 , 4DUM , 4TPW , 4TQB , 4TQC , 4UED , 5EHC , 5EI3 , 5EIR , 5EKV , 5GW6 , 5T46 , 5ZJY , 5ZJZ , 5ZK5 , 5ZK7 , 5ZK9 , 5ZML , 7D6Y , 7D8B , 7EZW , 7F07 , 7MEU , 7XTP , 8QM4 , 8QM5 , 8QM6 , 8QM7 , 8QM8 , 8QM9 , 8SX4 , 9DON

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01652	IF4E	38 → 197	Eukaryotic initiation factor 4E	Domain

Sequence

MATVEPETTPTPNPPTTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANL
RLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQ
QRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIG
RVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV

Sequence length

217

Interactions

View interactions

	KEGG		Reactome
	EGFR tyrosine kinase inhibitor resistance HIF-1 signaling pathway mTOR signaling pathway PI3K-Akt signaling pathway Longevity regulating pathway Insulin signaling pathway		ISG15 antiviral mechanism L13a-mediated translational silencing of Ceruloplasmin expression Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript mTORC1-mediated signalling Deadenylation of mRNA Translation initiation complex formation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit

Associated diseases

Show/Hide Causal Diseases (1)

Causal
Disease name	Disease term	dbSNP ID	References
Autism	NON RARE IN EUROPE: Autism, Autistic Disorder	rs121964908, rs121912597, rs2710102, rs7794745, rs142990298, rs62643608, rs181327458, rs797046134, rs869312704, rs1555013332, rs876657679, rs1057518999, rs1057518658, rs771827120, rs1555187899, rs773080572, rs753871454, rs1684130791, rs1684180699, rs1553510219, rs1684182454, rs1559060428, rs1553510677, rs1576352885, rs1574152522, rs1574152672, rs1696658542, rs1751123722, rs1750373491, rs1751075634

Show/Hide Unknown Diseases (3)

Unknown
Disease name	Disease term	dbSNP ID	References
Biliary cirrhosis	Biliary cirrhosis, Primary biliary cirrhosis		23000144
Malignant lymphoma, lymphocytic, intermediate differentiation	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse		17148679
Lymphoma, lymphocytic, intermediate	Lymphoma, Lymphocytic, Intermediate		17148679

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