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EGR1 (early growth response 1)

Gene

1958

Early growth response 1

EGR1

AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZIF268, ZNF225

5q31.2

The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis

Show/Hide all(549)

miRTarBase ID	miRNA	Experiments	Reference
MIRT004130	hsa-miR-192-5p	Microarray	16822819
MIRT006540	hsa-miR-183-5p	Luciferase reporter assay	21118966
MIRT006540	hsa-miR-183-5p	Luciferase reporter assay	21118966
MIRT023192	hsa-miR-124-3p	Microarray	18668037
MIRT024271	hsa-miR-215-5p	Microarray	19074876
MIRT004130	hsa-miR-192-5p	Microarray	19074876
MIRT054161	hsa-miR-191-5p	Immunoprecipitation, In situ hybridization, Luciferase assay, Microarray, Northern blot, QRTPCR, Western blot	23505378
MIRT440745	hsa-miR-487a-3p	HITS-CLIP	24374217
MIRT440744	hsa-miR-377-3p	HITS-CLIP	24374217
MIRT440745	hsa-miR-487a-3p	HITS-CLIP	24374217
MIRT440744	hsa-miR-377-3p	HITS-CLIP	24374217
MIRT023192	hsa-miR-124-3p	Luciferase reporter assay, Western blot	27569005
MIRT736969	hsa-miR-92a-3p	Western blotting, qRT-PCR	31545429
MIRT738417	hsa-miR-3684	HITS-CLIP	33718276
MIRT738419	hsa-miR-548s	HITS-CLIP	33718276
MIRT738420	hsa-miR-4701-5p	HITS-CLIP	33718276
MIRT738421	hsa-miR-4435	HITS-CLIP	33718276
MIRT738422	hsa-miR-3187-3p	HITS-CLIP	33718276
MIRT954924	hsa-miR-1207-5p	CLIP-seq
MIRT954925	hsa-miR-1261	CLIP-seq
MIRT954926	hsa-miR-1264	CLIP-seq
MIRT954927	hsa-miR-1288	CLIP-seq
MIRT954928	hsa-miR-129-5p	CLIP-seq
MIRT954929	hsa-miR-132	CLIP-seq
MIRT738400	hsa-miR-146a	CLIP-seq
MIRT738399	hsa-miR-146b-5p	CLIP-seq
MIRT954930	hsa-miR-183	CLIP-seq
MIRT954931	hsa-miR-1909	CLIP-seq
MIRT954932	hsa-miR-191	CLIP-seq
MIRT954933	hsa-miR-192	CLIP-seq
MIRT954934	hsa-miR-200b	CLIP-seq
MIRT954935	hsa-miR-200c	CLIP-seq
MIRT954936	hsa-miR-203	CLIP-seq
MIRT954937	hsa-miR-212	CLIP-seq
MIRT954938	hsa-miR-215	CLIP-seq
MIRT954939	hsa-miR-3064-3p	CLIP-seq
MIRT954940	hsa-miR-3119	CLIP-seq
MIRT954941	hsa-miR-3121-3p	CLIP-seq
MIRT954942	hsa-miR-3125	CLIP-seq
MIRT954943	hsa-miR-3136-3p	CLIP-seq
MIRT954944	hsa-miR-3183	CLIP-seq
MIRT954945	hsa-miR-3184	CLIP-seq
MIRT954946	hsa-miR-3185	CLIP-seq
MIRT954947	hsa-miR-3194-3p	CLIP-seq
MIRT954948	hsa-miR-3199	CLIP-seq
MIRT954949	hsa-miR-3202	CLIP-seq
MIRT954950	hsa-miR-3545-3p	CLIP-seq
MIRT954951	hsa-miR-3607-5p	CLIP-seq
MIRT954952	hsa-miR-3613-3p	CLIP-seq
MIRT954953	hsa-miR-361-3p	CLIP-seq
MIRT954954	hsa-miR-3679-3p	CLIP-seq
MIRT954955	hsa-miR-3914	CLIP-seq
MIRT954956	hsa-miR-3916	CLIP-seq
MIRT738404	hsa-miR-3921	CLIP-seq
MIRT954957	hsa-miR-3928	CLIP-seq
MIRT954958	hsa-miR-3942-3p	CLIP-seq
MIRT954959	hsa-miR-3973	CLIP-seq
MIRT954960	hsa-miR-423-5p	CLIP-seq
MIRT738401	hsa-miR-4251	CLIP-seq
MIRT954961	hsa-miR-4256	CLIP-seq
MIRT954962	hsa-miR-4269	CLIP-seq
MIRT954963	hsa-miR-4279	CLIP-seq
MIRT954964	hsa-miR-429	CLIP-seq
MIRT738402	hsa-miR-4329	CLIP-seq
MIRT954965	hsa-miR-4421	CLIP-seq
MIRT954966	hsa-miR-4436b-3p	CLIP-seq
MIRT954967	hsa-miR-4446-5p	CLIP-seq
MIRT954968	hsa-miR-4503	CLIP-seq
MIRT954969	hsa-miR-4511	CLIP-seq
MIRT954970	hsa-miR-4514	CLIP-seq
MIRT954971	hsa-miR-4529-5p	CLIP-seq
MIRT954972	hsa-miR-4533	CLIP-seq
MIRT954973	hsa-miR-4643	CLIP-seq
MIRT954974	hsa-miR-4649-3p	CLIP-seq
MIRT738403	hsa-miR-4653-5p	CLIP-seq
MIRT954975	hsa-miR-4667-3p	CLIP-seq
MIRT954976	hsa-miR-4668-3p	CLIP-seq
MIRT954977	hsa-miR-4687-3p	CLIP-seq
MIRT954978	hsa-miR-4692	CLIP-seq
MIRT954979	hsa-miR-4693-3p	CLIP-seq
MIRT954980	hsa-miR-4699-3p	CLIP-seq
MIRT954981	hsa-miR-4704-3p	CLIP-seq
MIRT954982	hsa-miR-4714-5p	CLIP-seq
MIRT954983	hsa-miR-4715-3p	CLIP-seq
MIRT954984	hsa-miR-4719	CLIP-seq
MIRT954985	hsa-miR-4723-3p	CLIP-seq
MIRT954986	hsa-miR-4731-3p	CLIP-seq
MIRT954987	hsa-miR-4733-5p	CLIP-seq
MIRT954988	hsa-miR-4742-5p	CLIP-seq
MIRT954989	hsa-miR-4763-3p	CLIP-seq
MIRT954990	hsa-miR-4775	CLIP-seq
MIRT954991	hsa-miR-4776-3p	CLIP-seq
MIRT954992	hsa-miR-4789-5p	CLIP-seq
MIRT954993	hsa-miR-4801	CLIP-seq
MIRT954994	hsa-miR-518a-3p	CLIP-seq
MIRT954995	hsa-miR-518b	CLIP-seq
MIRT954996	hsa-miR-518c	CLIP-seq
MIRT954997	hsa-miR-518d-3p	CLIP-seq
MIRT954998	hsa-miR-518f	CLIP-seq
MIRT954999	hsa-miR-520d-5p	CLIP-seq
MIRT955000	hsa-miR-524-5p	CLIP-seq
MIRT955001	hsa-miR-548a-5p	CLIP-seq
MIRT955002	hsa-miR-548ab	CLIP-seq
MIRT955003	hsa-miR-548ad	CLIP-seq
MIRT955004	hsa-miR-548ak	CLIP-seq
MIRT955005	hsa-miR-548b-5p	CLIP-seq
MIRT955006	hsa-miR-548c-5p	CLIP-seq
MIRT955007	hsa-miR-548d-5p	CLIP-seq
MIRT955008	hsa-miR-548h	CLIP-seq
MIRT955009	hsa-miR-548i	CLIP-seq
MIRT955010	hsa-miR-548j	CLIP-seq
MIRT955011	hsa-miR-548w	CLIP-seq
MIRT955012	hsa-miR-548y	CLIP-seq
MIRT955013	hsa-miR-559	CLIP-seq
MIRT955014	hsa-miR-580	CLIP-seq
MIRT955015	hsa-miR-581	CLIP-seq
MIRT738398	hsa-miR-589	CLIP-seq
MIRT955016	hsa-miR-590-3p	CLIP-seq
MIRT955017	hsa-miR-607	CLIP-seq
MIRT955018	hsa-miR-624	CLIP-seq
MIRT955019	hsa-miR-642b	CLIP-seq
MIRT738405	hsa-miR-760	CLIP-seq
MIRT955020	hsa-miR-877	CLIP-seq
MIRT955021	hsa-miR-9	CLIP-seq
MIRT955022	hsa-miR-935	CLIP-seq
MIRT954980	hsa-miR-4699-3p	CLIP-seq
MIRT954999	hsa-miR-520d-5p	CLIP-seq
MIRT955000	hsa-miR-524-5p	CLIP-seq
MIRT1982812	hsa-miR-1179	CLIP-seq
MIRT954924	hsa-miR-1207-5p	CLIP-seq
MIRT1982813	hsa-miR-1236	CLIP-seq
MIRT954926	hsa-miR-1264	CLIP-seq
MIRT1982814	hsa-miR-1270	CLIP-seq
MIRT1982815	hsa-miR-1272	CLIP-seq
MIRT954927	hsa-miR-1288	CLIP-seq
MIRT954928	hsa-miR-129-5p	CLIP-seq
MIRT954929	hsa-miR-132	CLIP-seq
MIRT1982816	hsa-miR-1322	CLIP-seq
MIRT1982817	hsa-miR-143	CLIP-seq
MIRT1982818	hsa-miR-150	CLIP-seq
MIRT954930	hsa-miR-183	CLIP-seq
MIRT954931	hsa-miR-1909	CLIP-seq
MIRT954932	hsa-miR-191	CLIP-seq
MIRT954934	hsa-miR-200b	CLIP-seq
MIRT954935	hsa-miR-200c	CLIP-seq
MIRT954936	hsa-miR-203	CLIP-seq
MIRT1982819	hsa-miR-2110	CLIP-seq
MIRT954937	hsa-miR-212	CLIP-seq
MIRT1982820	hsa-miR-217	CLIP-seq
MIRT1982821	hsa-miR-25	CLIP-seq
MIRT954939	hsa-miR-3064-3p	CLIP-seq
MIRT954941	hsa-miR-3121-3p	CLIP-seq
MIRT954942	hsa-miR-3125	CLIP-seq
MIRT1982822	hsa-miR-3134	CLIP-seq
MIRT954943	hsa-miR-3136-3p	CLIP-seq
MIRT1982823	hsa-miR-3140-5p	CLIP-seq
MIRT1982824	hsa-miR-3150a-3p	CLIP-seq
MIRT1982825	hsa-miR-3179	CLIP-seq
MIRT954944	hsa-miR-3183	CLIP-seq
MIRT954945	hsa-miR-3184	CLIP-seq
MIRT954947	hsa-miR-3194-3p	CLIP-seq
MIRT954948	hsa-miR-3199	CLIP-seq
MIRT1982826	hsa-miR-32	CLIP-seq
MIRT954949	hsa-miR-3202	CLIP-seq
MIRT954950	hsa-miR-3545-3p	CLIP-seq
MIRT954951	hsa-miR-3607-5p	CLIP-seq
MIRT954952	hsa-miR-3613-3p	CLIP-seq
MIRT954953	hsa-miR-361-3p	CLIP-seq
MIRT1982827	hsa-miR-363	CLIP-seq
MIRT1982828	hsa-miR-3660	CLIP-seq
MIRT1982829	hsa-miR-367	CLIP-seq
MIRT1982830	hsa-miR-3682-3p	CLIP-seq
MIRT1982831	hsa-miR-377	CLIP-seq
MIRT954955	hsa-miR-3914	CLIP-seq
MIRT954956	hsa-miR-3916	CLIP-seq
MIRT738404	hsa-miR-3921	CLIP-seq
MIRT954957	hsa-miR-3928	CLIP-seq
MIRT1982832	hsa-miR-3936	CLIP-seq
MIRT954959	hsa-miR-3973	CLIP-seq
MIRT954960	hsa-miR-423-5p	CLIP-seq
MIRT738401	hsa-miR-4251	CLIP-seq
MIRT954962	hsa-miR-4269	CLIP-seq
MIRT1982833	hsa-miR-4271	CLIP-seq
MIRT954963	hsa-miR-4279	CLIP-seq
MIRT954964	hsa-miR-429	CLIP-seq
MIRT738402	hsa-miR-4329	CLIP-seq
MIRT954965	hsa-miR-4421	CLIP-seq
MIRT1982834	hsa-miR-4427	CLIP-seq
MIRT954966	hsa-miR-4436b-3p	CLIP-seq
MIRT738424	hsa-miR-4445	CLIP-seq
MIRT954968	hsa-miR-4503	CLIP-seq
MIRT954970	hsa-miR-4514	CLIP-seq
MIRT1982835	hsa-miR-4526	CLIP-seq
MIRT954971	hsa-miR-4529-5p	CLIP-seq
MIRT954972	hsa-miR-4533	CLIP-seq
MIRT1982836	hsa-miR-4534	CLIP-seq
MIRT954973	hsa-miR-4643	CLIP-seq
MIRT954974	hsa-miR-4649-3p	CLIP-seq
MIRT738403	hsa-miR-4653-5p	CLIP-seq
MIRT954975	hsa-miR-4667-3p	CLIP-seq
MIRT954976	hsa-miR-4668-3p	CLIP-seq
MIRT1982837	hsa-miR-4683	CLIP-seq
MIRT954977	hsa-miR-4687-3p	CLIP-seq
MIRT1982838	hsa-miR-4687-5p	CLIP-seq
MIRT1982839	hsa-miR-4690-3p	CLIP-seq
MIRT954978	hsa-miR-4692	CLIP-seq
MIRT954979	hsa-miR-4693-3p	CLIP-seq
MIRT954980	hsa-miR-4699-3p	CLIP-seq
MIRT954981	hsa-miR-4704-3p	CLIP-seq
MIRT1982840	hsa-miR-4708-3p	CLIP-seq
MIRT954984	hsa-miR-4719	CLIP-seq
MIRT954985	hsa-miR-4723-3p	CLIP-seq
MIRT1982841	hsa-miR-4724-5p	CLIP-seq
MIRT1982842	hsa-miR-4725-3p	CLIP-seq
MIRT954986	hsa-miR-4731-3p	CLIP-seq
MIRT954987	hsa-miR-4733-5p	CLIP-seq
MIRT954988	hsa-miR-4742-5p	CLIP-seq
MIRT1982843	hsa-miR-4747-5p	CLIP-seq
MIRT954989	hsa-miR-4763-3p	CLIP-seq
MIRT1982844	hsa-miR-4770	CLIP-seq
MIRT954991	hsa-miR-4776-3p	CLIP-seq
MIRT1982845	hsa-miR-4795-5p	CLIP-seq
MIRT954993	hsa-miR-4801	CLIP-seq
MIRT954994	hsa-miR-518a-3p	CLIP-seq
MIRT954995	hsa-miR-518b	CLIP-seq
MIRT954996	hsa-miR-518c	CLIP-seq
MIRT954997	hsa-miR-518d-3p	CLIP-seq
MIRT954998	hsa-miR-518f	CLIP-seq
MIRT954999	hsa-miR-520d-5p	CLIP-seq
MIRT1982846	hsa-miR-524-3p	CLIP-seq
MIRT955000	hsa-miR-524-5p	CLIP-seq
MIRT1982847	hsa-miR-525-3p	CLIP-seq
MIRT1982848	hsa-miR-543	CLIP-seq
MIRT1982849	hsa-miR-545	CLIP-seq
MIRT955001	hsa-miR-548a-5p	CLIP-seq
MIRT955002	hsa-miR-548ab	CLIP-seq
MIRT955004	hsa-miR-548ak	CLIP-seq
MIRT955005	hsa-miR-548b-5p	CLIP-seq
MIRT955006	hsa-miR-548c-5p	CLIP-seq
MIRT955007	hsa-miR-548d-5p	CLIP-seq
MIRT955008	hsa-miR-548h	CLIP-seq
MIRT955009	hsa-miR-548i	CLIP-seq
MIRT955010	hsa-miR-548j	CLIP-seq
MIRT955011	hsa-miR-548w	CLIP-seq
MIRT955012	hsa-miR-548y	CLIP-seq
MIRT955013	hsa-miR-559	CLIP-seq
MIRT955014	hsa-miR-580	CLIP-seq
MIRT955015	hsa-miR-581	CLIP-seq
MIRT1982850	hsa-miR-606	CLIP-seq
MIRT955017	hsa-miR-607	CLIP-seq
MIRT1982851	hsa-miR-620	CLIP-seq
MIRT955018	hsa-miR-624	CLIP-seq
MIRT955019	hsa-miR-642b	CLIP-seq
MIRT738405	hsa-miR-760	CLIP-seq
MIRT955020	hsa-miR-877	CLIP-seq
MIRT1982852	hsa-miR-92a	CLIP-seq
MIRT1982853	hsa-miR-92b	CLIP-seq
MIRT1982812	hsa-miR-1179	CLIP-seq
MIRT954924	hsa-miR-1207-5p	CLIP-seq
MIRT2217814	hsa-miR-124	CLIP-seq
MIRT954925	hsa-miR-1261	CLIP-seq
MIRT954927	hsa-miR-1288	CLIP-seq
MIRT954929	hsa-miR-132	CLIP-seq
MIRT738400	hsa-miR-146a	CLIP-seq
MIRT738399	hsa-miR-146b-5p	CLIP-seq
MIRT1982818	hsa-miR-150	CLIP-seq
MIRT954930	hsa-miR-183	CLIP-seq
MIRT954931	hsa-miR-1909	CLIP-seq
MIRT954932	hsa-miR-191	CLIP-seq
MIRT2217815	hsa-miR-1911	CLIP-seq
MIRT2217816	hsa-miR-1913	CLIP-seq
MIRT954933	hsa-miR-192	CLIP-seq
MIRT954934	hsa-miR-200b	CLIP-seq
MIRT954935	hsa-miR-200c	CLIP-seq
MIRT954937	hsa-miR-212	CLIP-seq
MIRT954938	hsa-miR-215	CLIP-seq
MIRT2217817	hsa-miR-23a	CLIP-seq
MIRT2217818	hsa-miR-23b	CLIP-seq
MIRT2217819	hsa-miR-23c	CLIP-seq
MIRT1982821	hsa-miR-25	CLIP-seq
MIRT954939	hsa-miR-3064-3p	CLIP-seq
MIRT954940	hsa-miR-3119	CLIP-seq
MIRT954941	hsa-miR-3121-3p	CLIP-seq
MIRT954942	hsa-miR-3125	CLIP-seq
MIRT954943	hsa-miR-3136-3p	CLIP-seq
MIRT1982825	hsa-miR-3179	CLIP-seq
MIRT954945	hsa-miR-3184	CLIP-seq
MIRT954947	hsa-miR-3194-3p	CLIP-seq
MIRT954948	hsa-miR-3199	CLIP-seq
MIRT1982826	hsa-miR-32	CLIP-seq
MIRT2217820	hsa-miR-324-3p	CLIP-seq
MIRT2217821	hsa-miR-335	CLIP-seq
MIRT954951	hsa-miR-3607-5p	CLIP-seq
MIRT954952	hsa-miR-3613-3p	CLIP-seq
MIRT954953	hsa-miR-361-3p	CLIP-seq
MIRT1982827	hsa-miR-363	CLIP-seq
MIRT1982828	hsa-miR-3660	CLIP-seq
MIRT1982829	hsa-miR-367	CLIP-seq
MIRT1982831	hsa-miR-377	CLIP-seq
MIRT954955	hsa-miR-3914	CLIP-seq
MIRT954956	hsa-miR-3916	CLIP-seq
MIRT738404	hsa-miR-3921	CLIP-seq
MIRT738418	hsa-miR-3926	CLIP-seq
MIRT954957	hsa-miR-3928	CLIP-seq
MIRT1982832	hsa-miR-3936	CLIP-seq
MIRT2217822	hsa-miR-412	CLIP-seq
MIRT954960	hsa-miR-423-5p	CLIP-seq
MIRT738401	hsa-miR-4251	CLIP-seq
MIRT954961	hsa-miR-4256	CLIP-seq
MIRT954962	hsa-miR-4269	CLIP-seq
MIRT954964	hsa-miR-429	CLIP-seq
MIRT2217823	hsa-miR-4313	CLIP-seq
MIRT738402	hsa-miR-4329	CLIP-seq
MIRT954966	hsa-miR-4436b-3p	CLIP-seq
MIRT738424	hsa-miR-4445	CLIP-seq
MIRT954970	hsa-miR-4514	CLIP-seq
MIRT1982835	hsa-miR-4526	CLIP-seq
MIRT954973	hsa-miR-4643	CLIP-seq
MIRT954974	hsa-miR-4649-3p	CLIP-seq
MIRT738403	hsa-miR-4653-5p	CLIP-seq
MIRT954976	hsa-miR-4668-3p	CLIP-seq
MIRT954978	hsa-miR-4692	CLIP-seq
MIRT954979	hsa-miR-4693-3p	CLIP-seq
MIRT954980	hsa-miR-4699-3p	CLIP-seq
MIRT954981	hsa-miR-4704-3p	CLIP-seq
MIRT1982840	hsa-miR-4708-3p	CLIP-seq
MIRT954982	hsa-miR-4714-5p	CLIP-seq
MIRT954984	hsa-miR-4719	CLIP-seq
MIRT954987	hsa-miR-4733-5p	CLIP-seq
MIRT954988	hsa-miR-4742-5p	CLIP-seq
MIRT954989	hsa-miR-4763-3p	CLIP-seq
MIRT954991	hsa-miR-4776-3p	CLIP-seq
MIRT954992	hsa-miR-4789-5p	CLIP-seq
MIRT2217824	hsa-miR-4792	CLIP-seq
MIRT2217825	hsa-miR-483-3p	CLIP-seq
MIRT2217826	hsa-miR-506	CLIP-seq
MIRT954994	hsa-miR-518a-3p	CLIP-seq
MIRT954995	hsa-miR-518b	CLIP-seq
MIRT954996	hsa-miR-518c	CLIP-seq
MIRT954997	hsa-miR-518d-3p	CLIP-seq
MIRT954998	hsa-miR-518f	CLIP-seq
MIRT954999	hsa-miR-520d-5p	CLIP-seq
MIRT1982846	hsa-miR-524-3p	CLIP-seq
MIRT955000	hsa-miR-524-5p	CLIP-seq
MIRT1982847	hsa-miR-525-3p	CLIP-seq
MIRT1982849	hsa-miR-545	CLIP-seq
MIRT955003	hsa-miR-548ad	CLIP-seq
MIRT2217827	hsa-miR-548an	CLIP-seq
MIRT955014	hsa-miR-580	CLIP-seq
MIRT738423	hsa-miR-588	CLIP-seq
MIRT738398	hsa-miR-589	CLIP-seq
MIRT955017	hsa-miR-607	CLIP-seq
MIRT955018	hsa-miR-624	CLIP-seq
MIRT955019	hsa-miR-642b	CLIP-seq
MIRT738405	hsa-miR-760	CLIP-seq
MIRT955020	hsa-miR-877	CLIP-seq
MIRT955021	hsa-miR-9	CLIP-seq
MIRT1982852	hsa-miR-92a	CLIP-seq
MIRT1982853	hsa-miR-92b	CLIP-seq
MIRT955022	hsa-miR-935	CLIP-seq
MIRT954924	hsa-miR-1207-5p	CLIP-seq
MIRT954927	hsa-miR-1288	CLIP-seq
MIRT954931	hsa-miR-1909	CLIP-seq
MIRT954934	hsa-miR-200b	CLIP-seq
MIRT954935	hsa-miR-200c	CLIP-seq
MIRT1982821	hsa-miR-25	CLIP-seq
MIRT954943	hsa-miR-3136-3p	CLIP-seq
MIRT954945	hsa-miR-3184	CLIP-seq
MIRT954947	hsa-miR-3194-3p	CLIP-seq
MIRT954948	hsa-miR-3199	CLIP-seq
MIRT1982826	hsa-miR-32	CLIP-seq
MIRT954952	hsa-miR-3613-3p	CLIP-seq
MIRT1982827	hsa-miR-363	CLIP-seq
MIRT1982829	hsa-miR-367	CLIP-seq
MIRT738404	hsa-miR-3921	CLIP-seq
MIRT954960	hsa-miR-423-5p	CLIP-seq
MIRT738401	hsa-miR-4251	CLIP-seq
MIRT954964	hsa-miR-429	CLIP-seq
MIRT738402	hsa-miR-4329	CLIP-seq
MIRT954966	hsa-miR-4436b-3p	CLIP-seq
MIRT954973	hsa-miR-4643	CLIP-seq
MIRT954974	hsa-miR-4649-3p	CLIP-seq
MIRT738403	hsa-miR-4653-5p	CLIP-seq
MIRT1982840	hsa-miR-4708-3p	CLIP-seq
MIRT954989	hsa-miR-4763-3p	CLIP-seq
MIRT1982846	hsa-miR-524-3p	CLIP-seq
MIRT1982847	hsa-miR-525-3p	CLIP-seq
MIRT1982849	hsa-miR-545	CLIP-seq
MIRT955014	hsa-miR-580	CLIP-seq
MIRT955017	hsa-miR-607	CLIP-seq
MIRT955018	hsa-miR-624	CLIP-seq
MIRT955019	hsa-miR-642b	CLIP-seq
MIRT738405	hsa-miR-760	CLIP-seq
MIRT1982852	hsa-miR-92a	CLIP-seq
MIRT1982853	hsa-miR-92b	CLIP-seq
MIRT2428423	hsa-miR-199a-3p	CLIP-seq
MIRT2428424	hsa-miR-199b-3p	CLIP-seq
MIRT2428425	hsa-miR-3129-5p	CLIP-seq
MIRT954946	hsa-miR-3185	CLIP-seq
MIRT954962	hsa-miR-4269	CLIP-seq
MIRT954968	hsa-miR-4503	CLIP-seq
MIRT954969	hsa-miR-4511	CLIP-seq
MIRT954970	hsa-miR-4514	CLIP-seq
MIRT2428426	hsa-miR-4520a-3p	CLIP-seq
MIRT2428427	hsa-miR-4520b-3p	CLIP-seq
MIRT954977	hsa-miR-4687-3p	CLIP-seq
MIRT954978	hsa-miR-4692	CLIP-seq
MIRT954986	hsa-miR-4731-3p	CLIP-seq
MIRT954988	hsa-miR-4742-5p	CLIP-seq
MIRT2428428	hsa-miR-4797-3p	CLIP-seq
MIRT954993	hsa-miR-4801	CLIP-seq
MIRT2428429	hsa-miR-510	CLIP-seq
MIRT2428430	hsa-miR-512-5p	CLIP-seq
MIRT1982848	hsa-miR-543	CLIP-seq
MIRT2428431	hsa-miR-548c-3p	CLIP-seq
MIRT1982850	hsa-miR-606	CLIP-seq
MIRT2428432	hsa-miR-890	CLIP-seq
MIRT738411	hsa-miR-936	CLIP-seq
MIRT954924	hsa-miR-1207-5p	CLIP-seq
MIRT2436927	hsa-miR-1224-5p	CLIP-seq
MIRT2436928	hsa-miR-1273e	CLIP-seq
MIRT954927	hsa-miR-1288	CLIP-seq
MIRT738406	hsa-miR-1321	CLIP-seq
MIRT738400	hsa-miR-146a	CLIP-seq
MIRT738399	hsa-miR-146b-5p	CLIP-seq
MIRT954931	hsa-miR-1909	CLIP-seq
MIRT954934	hsa-miR-200b	CLIP-seq
MIRT954935	hsa-miR-200c	CLIP-seq
MIRT1982819	hsa-miR-2110	CLIP-seq
MIRT954940	hsa-miR-3119	CLIP-seq
MIRT954941	hsa-miR-3121-3p	CLIP-seq
MIRT954942	hsa-miR-3125	CLIP-seq
MIRT954943	hsa-miR-3136-3p	CLIP-seq
MIRT2436929	hsa-miR-3145-5p	CLIP-seq
MIRT1982824	hsa-miR-3150a-3p	CLIP-seq
MIRT1982825	hsa-miR-3179	CLIP-seq
MIRT954945	hsa-miR-3184	CLIP-seq
MIRT954947	hsa-miR-3194-3p	CLIP-seq
MIRT954948	hsa-miR-3199	CLIP-seq
MIRT954949	hsa-miR-3202	CLIP-seq
MIRT2436930	hsa-miR-338-5p	CLIP-seq
MIRT954953	hsa-miR-361-3p	CLIP-seq
MIRT954954	hsa-miR-3679-3p	CLIP-seq
MIRT2436931	hsa-miR-369-3p	CLIP-seq
MIRT2436932	hsa-miR-374c	CLIP-seq
MIRT954956	hsa-miR-3916	CLIP-seq
MIRT738404	hsa-miR-3921	CLIP-seq
MIRT738414	hsa-miR-3925-3p	CLIP-seq
MIRT738418	hsa-miR-3926	CLIP-seq
MIRT954960	hsa-miR-423-5p	CLIP-seq
MIRT738401	hsa-miR-4251	CLIP-seq
MIRT1982833	hsa-miR-4271	CLIP-seq
MIRT954964	hsa-miR-429	CLIP-seq
MIRT738402	hsa-miR-4329	CLIP-seq
MIRT738410	hsa-miR-4419a	CLIP-seq
MIRT954966	hsa-miR-4436b-3p	CLIP-seq
MIRT738416	hsa-miR-4436b-5p	CLIP-seq
MIRT738424	hsa-miR-4445	CLIP-seq
MIRT954967	hsa-miR-4446-5p	CLIP-seq
MIRT738409	hsa-miR-4510	CLIP-seq
MIRT954973	hsa-miR-4643	CLIP-seq
MIRT954974	hsa-miR-4649-3p	CLIP-seq
MIRT738403	hsa-miR-4653-5p	CLIP-seq
MIRT2436933	hsa-miR-4666-3p	CLIP-seq
MIRT738412	hsa-miR-4712-5p	CLIP-seq
MIRT954984	hsa-miR-4719	CLIP-seq
MIRT1982842	hsa-miR-4725-3p	CLIP-seq
MIRT738407	hsa-miR-4739	CLIP-seq
MIRT1982843	hsa-miR-4747-5p	CLIP-seq
MIRT2436934	hsa-miR-4751	CLIP-seq
MIRT738408	hsa-miR-4756-5p	CLIP-seq
MIRT954989	hsa-miR-4763-3p	CLIP-seq
MIRT2436935	hsa-miR-4764-3p	CLIP-seq
MIRT954991	hsa-miR-4776-3p	CLIP-seq
MIRT1982845	hsa-miR-4795-5p	CLIP-seq
MIRT738415	hsa-miR-508-5p	CLIP-seq
MIRT955014	hsa-miR-580	CLIP-seq
MIRT738423	hsa-miR-588	CLIP-seq
MIRT738398	hsa-miR-589	CLIP-seq
MIRT955018	hsa-miR-624	CLIP-seq
MIRT955019	hsa-miR-642b	CLIP-seq
MIRT2436936	hsa-miR-655	CLIP-seq
MIRT738405	hsa-miR-760	CLIP-seq
MIRT738413	hsa-miR-770-5p	CLIP-seq
MIRT955020	hsa-miR-877	CLIP-seq
MIRT738411	hsa-miR-936	CLIP-seq
MIRT1982812	hsa-miR-1179	CLIP-seq
MIRT954924	hsa-miR-1207-5p	CLIP-seq
MIRT954927	hsa-miR-1288	CLIP-seq
MIRT954931	hsa-miR-1909	CLIP-seq
MIRT954934	hsa-miR-200b	CLIP-seq
MIRT954935	hsa-miR-200c	CLIP-seq
MIRT954941	hsa-miR-3121-3p	CLIP-seq
MIRT954942	hsa-miR-3125	CLIP-seq
MIRT954943	hsa-miR-3136-3p	CLIP-seq
MIRT1982825	hsa-miR-3179	CLIP-seq
MIRT954945	hsa-miR-3184	CLIP-seq
MIRT954947	hsa-miR-3194-3p	CLIP-seq
MIRT954948	hsa-miR-3199	CLIP-seq
MIRT954952	hsa-miR-3613-3p	CLIP-seq
MIRT954956	hsa-miR-3916	CLIP-seq
MIRT738404	hsa-miR-3921	CLIP-seq
MIRT1982832	hsa-miR-3936	CLIP-seq
MIRT954960	hsa-miR-423-5p	CLIP-seq
MIRT738401	hsa-miR-4251	CLIP-seq
MIRT954962	hsa-miR-4269	CLIP-seq
MIRT954964	hsa-miR-429	CLIP-seq
MIRT738402	hsa-miR-4329	CLIP-seq
MIRT954966	hsa-miR-4436b-3p	CLIP-seq
MIRT954970	hsa-miR-4514	CLIP-seq
MIRT954973	hsa-miR-4643	CLIP-seq
MIRT954974	hsa-miR-4649-3p	CLIP-seq
MIRT738403	hsa-miR-4653-5p	CLIP-seq
MIRT954978	hsa-miR-4692	CLIP-seq
MIRT954984	hsa-miR-4719	CLIP-seq
MIRT954988	hsa-miR-4742-5p	CLIP-seq
MIRT954989	hsa-miR-4763-3p	CLIP-seq
MIRT954991	hsa-miR-4776-3p	CLIP-seq
MIRT955014	hsa-miR-580	CLIP-seq
MIRT955017	hsa-miR-607	CLIP-seq
MIRT955018	hsa-miR-624	CLIP-seq
MIRT955019	hsa-miR-642b	CLIP-seq
MIRT738405	hsa-miR-760	CLIP-seq
MIRT955020	hsa-miR-877	CLIP-seq
MIRT954924	hsa-miR-1207-5p	CLIP-seq
MIRT954927	hsa-miR-1288	CLIP-seq
MIRT954931	hsa-miR-1909	CLIP-seq
MIRT954934	hsa-miR-200b	CLIP-seq
MIRT954935	hsa-miR-200c	CLIP-seq
MIRT954943	hsa-miR-3136-3p	CLIP-seq
MIRT954945	hsa-miR-3184	CLIP-seq
MIRT954947	hsa-miR-3194-3p	CLIP-seq
MIRT954948	hsa-miR-3199	CLIP-seq
MIRT954952	hsa-miR-3613-3p	CLIP-seq
MIRT738404	hsa-miR-3921	CLIP-seq
MIRT954960	hsa-miR-423-5p	CLIP-seq
MIRT738401	hsa-miR-4251	CLIP-seq
MIRT954964	hsa-miR-429	CLIP-seq
MIRT738402	hsa-miR-4329	CLIP-seq
MIRT954966	hsa-miR-4436b-3p	CLIP-seq
MIRT954973	hsa-miR-4643	CLIP-seq
MIRT954974	hsa-miR-4649-3p	CLIP-seq
MIRT738403	hsa-miR-4653-5p	CLIP-seq
MIRT954989	hsa-miR-4763-3p	CLIP-seq
MIRT955014	hsa-miR-580	CLIP-seq
MIRT955017	hsa-miR-607	CLIP-seq
MIRT955018	hsa-miR-624	CLIP-seq
MIRT955019	hsa-miR-642b	CLIP-seq
MIRT738405	hsa-miR-760	CLIP-seq

Transcription factors

Show/Hide all(15)

Transcription factor	Regulation	Reference
ATF5	Unknown	19531563
BRCA1	Unknown	20103632
ETS1	Activation	19074849
ETS1	Unknown	9207063
ETS2	Unknown	9207063
FOXO1	Repression	22865884
HDAC1	Repression	21983014
MAML1	Activation	23029358
NFKB1	Repression	21983014
NKX2-3	Unknown	21968973
RBMX	Repression	16707624
RELA	Repression	21983014
SP1	Activation	8349585
SP1	Unknown	10826704
TP53	Unknown	16990849

Show/Hide all(61)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0000785	Component	Chromatin	IDA	19307576
GO:0000785	Component	Chromatin	ISA
GO:0000976	Function	Transcription regulatory region sequence-specific DNA binding	IDA	18718911
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	14979875, 19307576
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	19307576
GO:0001666	Process	Response to hypoxia	ISS
GO:0002931	Process	Response to ischemia	ISS
GO:0003677	Function	DNA binding	IDA	12560508
GO:0003700	Function	DNA-binding transcription factor activity	IDA	12560508
GO:0005515	Function	Protein binding	IPI	19057511, 21743491
GO:0005634	Component	Nucleus	IDA	19057511, 20018936, 20363028
GO:0005634	Component	Nucleus	ISS
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IDA	19057511, 20363028
GO:0005737	Component	Cytoplasm	ISS
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0008270	Function	Zinc ion binding	IDA	25258363
GO:0009749	Process	Response to glucose	IEA
GO:0010385	Function	Double-stranded methylated DNA binding	IDA	25258363
GO:0010628	Process	Positive regulation of gene expression	IMP	24244514
GO:0030217	Process	T cell differentiation	IEA
GO:0030509	Process	BMP signaling pathway	IEA
GO:0032722	Process	Positive regulation of chemokine production	ISS
GO:0032731	Process	Positive regulation of interleukin-1 beta production	ISS
GO:0032868	Process	Response to insulin	IEA
GO:0032922	Process	Circadian regulation of gene expression	ISS
GO:0033233	Process	Regulation of protein sumoylation	IDA	19057511
GO:0035035	Function	Histone acetyltransferase binding	IPI	20018936
GO:0035914	Process	Skeletal muscle cell differentiation	IEA
GO:0042981	Process	Regulation of apoptotic process	IEA
GO:0043565	Function	Sequence-specific DNA binding	IDA	1662794, 25258363
GO:0044729	Function	Hemi-methylated DNA-binding	IDA	25258363
GO:0044849	Process	Estrous cycle	ISS
GO:0045475	Process	Locomotor rhythm	ISS
GO:0045893	Process	Positive regulation of transcription, DNA-templated	IDA	12560508
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	19057511, 26089202
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IGI	14979875
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IMP	14979875, 20018936
GO:0046886	Process	Positive regulation of hormone biosynthetic process	ISS
GO:0060086	Process	Circadian temperature homeostasis	ISS
GO:0060337	Process	Type I interferon signaling pathway	TAS
GO:0061418	Process	Regulation of transcription from RNA polymerase II promoter in response to hypoxia	IEA
GO:0070498	Process	Interleukin-1-mediated signaling pathway	IMP	20018936
GO:0071480	Process	Cellular response to gamma radiation	IEA
GO:0071504	Process	Cellular response to heparin	ISS
GO:0071506	Process	Cellular response to mycophenolic acid	ISS
GO:0072110	Process	Glomerular mesangial cell proliferation	ISS
GO:0072303	Process	Positive regulation of glomerular metanephric mesangial cell proliferation	ISS
GO:0090090	Process	Negative regulation of canonical Wnt signaling pathway	IEA
GO:0098759	Process	Cellular response to interleukin-8	IDA	20363028
GO:1901216	Process	Positive regulation of neuron death	ISS
GO:1902895	Process	Positive regulation of pri-miRNA transcription by RNA polymerase II	IDA	19307576
GO:1902949	Process	Positive regulation of tau-protein kinase activity	ISS
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536
GO:1990841	Function	Promoter-specific chromatin binding	IDA	20363028
GO:2000182	Process	Regulation of progesterone biosynthetic process	ISS

MIM	HGNC	e!Ensembl
128990	3238	ENSG00000120738

Protein

UniProt ID

P18146

Protein name

Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24)

Protein function

Transcriptional regulator (PubMed:20121949). Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity). Binds double-stranded target DNA, irrespective of the cytosine methylatio

PDB

4R2A , 4R2C , 4R2D , 4X9J , 5N14

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF11928	DUF3446	135 → 219	Early growth response N-terminal domain	Domain
PF00096	zf-C2H2	338 → 362	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	368 → 390	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	396 → 418	Zinc finger, C2H2 type	Domain
PF11914	DUF3432	424 → 462	Domain of unknown function (DUF3432)	Repeat
PF11914	DUF3432	452 → 530	Domain of unknown function (DUF3432)	Repeat

Sequence

MAAAKAEMQLMSPLQISDPFGSFPHSPTMDNYPKLEEMMLLSNGAPQFLGAAGAPEGSGS
NSSSSSSGGGGGGGGGSNSSSSSSTFNPQADTGEQPYEHLTAESFPDISLNNEKVLVETS
YPSQTTRLPPITYTGRFSLEPAPNSGNTLWPEPLFSLVSGLVSMTNPPASSSSAPSPAAS
SASASQSPPLSCAVPSNDSSPIYSAAPTFPTPNTDIFPEPQSQAFPGSAGTALQYPPPAY
PAAKGGFQVPMIPDYLFPQQQGDLGLGTPDQKPFQGLESRTQQPSLTPLSTIKAFATQSG
SQDLKALNTSYQSQLIKPSRMRKYPNRPSKTPPHERPYACPVESCDRRFSRSDELTRHIR
IHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLR
QKDKKADKSVVASSATSSLSSYPSPVATSYPSPVTTSYPSPATTSYPSPVPTSFSSPGSS
TYPSPVHSGFPSPSVATTYSSVPPAFPAQVSSFPSSAVTNSFSASTGLSDMTATFSPRTI
EIC

Sequence length

543

Interactions

View interactions

	KEGG		Reactome
	Apelin signaling pathway GnRH signaling pathway Parathyroid hormone synthesis, secretion and action AGE-RAGE signaling pathway in diabetic complications Prion disease Human T-cell leukemia virus 1 infection		Regulation of PTEN gene transcription NGF-stimulated transcription Interferon alpha/beta signaling

Associated diseases

Show/Hide Causal Diseases (7)

Causal
Disease name	Disease term	dbSNP ID	References
Arthritis	Juvenile arthritis	rs1594890601, rs1594882933, rs184370809, rs776489319, rs1594883470	19565504
Autoimmune diseases	Autoimmune Diseases	rs41285370, rs869025224	25055964
Cholestasis	Cholestasis	rs121909103, rs751511532, rs376368459, rs762702807, rs1578490102, rs1578499691, rs1578504946, rs1317656688, rs199791850, rs1452792080, rs1578491039	21224055
Intrahepatic cholestasis	Intrahepatic Cholestasis	rs121918299, rs80338722, rs80338725, rs80338719, rs80338723, rs80338726, rs72549401, rs11568372, rs1553469602, rs387907317, rs387906354, rs752919965, rs72549397, rs111033609, rs121909099, rs387906381, rs121909100, rs121909101, rs121909104, rs121909105, rs387906526, rs121918440, rs387906527, rs72552778, rs387906529, rs121918443, rs72552780, rs80338724, rs80338715, rs80338727, rs80338729, rs80338716, rs80338717, rs398122839, rs515726137, rs587777519, rs587777520, rs587777521, rs879255644, rs113090017, rs864321695, rs776869985, rs864321697, rs80338720, rs746155190, rs879255504, rs886041948, rs886042562, rs769910565, rs758069019, rs886043807, rs72549402, rs72549395, rs188824058, rs763782349, rs375315619, rs754287486, rs1057518679, rs1060499649, rs1060499579, rs1554660803, rs1554407511, rs774824767, rs771690686, rs752992432, rs1553466082, rs72549396, rs772294884, rs764513998, rs1202682161, rs759202962, rs1562774655, rs1562831765, rs1562945221, rs917981474, rs1558927163, rs765889649, rs1562976061, rs72549399, rs1459273753, rs377160065, rs1559183717, rs760750012, rs1051861187, rs1558898789, rs928915940, rs752757689, rs1584678508, rs764581483, rs1574453508, rs751511532, rs1182781290, rs376368459, rs762702807, rs1578499691, rs199791850, rs1452792080, rs1458423947, rs1584747270, rs1584750653, rs1599066459, rs1599069873, rs1599166106, rs1574462504, rs1593114820, rs1057524081, rs1588081022, rs777460754, rs1251192873, rs1588117076, rs748671901, rs139314808, rs749009273, rs1588080674, rs1588080680, rs1588127136, rs1588135086, rs757693457, rs1574445178, rs768922690, rs1584422832, rs1584433525, rs1312396424, rs1792048079, rs774411820, rs575729461	22094456, 18364083
Lung cancer	Malignant neoplasm of lung	rs121913530, rs121913529, rs878855122, rs1057519784, rs770315135	27935865
Mesothelioma	Mesothelioma	rs121907908, rs387906350, rs387906351	15878867
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	16552752

Show/Hide Unknown Diseases (10)

Unknown
Disease name	Disease term	dbSNP ID	References
Cerebral ischemia	Brain Ischemia		17394460
Cholangitis	Cholangitis		25055964
Hydronephrosis	Hydronephrosis		25015655
Juvenile arthritis	Juvenile psoriatic arthritis		19565504
Liver carcinoma	Liver carcinoma		28284560
Lung neoplasms	Lung Neoplasms		27935865
Seronegative polyarthritis	Polyarthritis, Juvenile, Rheumatoid Factor Negative		19565504
Polyarthritis, rheumatoid factor positive	Polyarthritis, Juvenile, Rheumatoid Factor Positive		19565504
Prostatic neoplasms	Prostatic Neoplasms		16552752
Still disease	Juvenile-Onset Still Disease		19565504

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