GediPNet logo

MIER3 (MIER family member 3)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
166968
Gene nameGene Name - the full gene name approved by the HGNC.
MIER family member 3
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
MIER3
SynonymsGene synonyms aliases
-
ChromosomeChromosome number
5
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q11.2
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT016054 hsa-miR-374b-5p Sequencing 20371350
MIRT016182 hsa-miR-590-3p Sequencing 20371350
MIRT019243 hsa-miR-331-3p Sequencing 20371350
MIRT021919 hsa-miR-128-3p Sequencing 20371350
MIRT023461 hsa-miR-30b-5p Sequencing 20371350
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IBA 21873635
GO:0001103 Function RNA polymerase II repressing transcription factor binding IBA 21873635
GO:0003714 Function Transcription corepressor activity IBA 21873635
GO:0004407 Function Histone deacetylase activity IDA 28046085
GO:0005634 Component Nucleus IDA 28046085
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q7Z3K6
Protein name Mesoderm induction early response protein 3 (Mi-er3)
Protein function Transcriptional repressor.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01448 ELM2
176 226
ELM2 domain
Family
PF00249 Myb_DNA-binding
279 325
Myb-like DNA-binding domain
Domain
Sequence
MAEASFGSSSPVGSLSSEDHDFDPTAEMLVHDYDDERTLEEEEMMDEGKNFSSEIEDLEK
EGTMPLEDLLAFYGYEPTIPAVANSSANSSPSELADELPDMTLDKEEIAKDLLSGDDEET
QSSADDLTPSVTSHETSDFFPRPLRSNTACDGDKESEVEDVETDSGNSPEDLRKEIMIGL
QYQAEIPPYLGEYDGNEKVYENEDQLLWCPDVVLESKVKEYLVETS
LRTGSEKIMDRISA
GTHTRDNEQALYELLKCNHNIKEAIERYCCNGKASQEGMTAWTEEECRSFEHALMLFGKD
FHLIQKNKVRTRTVAECVAFYYMWK
KSERYDYFAQQTRFGKKRYNHHPGVTDYMDRLVDE
TEALGGTVNASALTSNRPEPIPDQQLNILNSFTASDLTALTNSVATVCDPTDVNCLDDSF
PPLGNTPRGQVNHVPVVTEELLTLPSNGESDCFNLFETGFYHSELNPMNMCSEESERPAK
RLKMGIAVPESFMNEVSVNNLGVDFENHTHHITSAKMAVSVADFGSLSANETNGFISAHA
LHQHAALHSE
Sequence length 550
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Breast carcinoma Breast Carcinoma rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451, rs397507859, rs80359709, rs80359742, rs80359205, rs80357627, rs80357004, rs80357571, rs80357767, rs80357653, rs80358086, rs80357608, rs28897696, rs41293465, rs146650273, rs63751017, rs63750617, rs63750726, rs63750199, rs63749848, rs398122618, rs398122653, rs397509211, rs80357791, rs121912666, rs587778541, rs121908698, rs536907995, rs587781302, rs140342925, rs587781506, rs587782652, rs587782849, rs587783057, rs10520699, rs11852999, rs139770721, rs374950566, rs786202800, rs863224451, rs377153250, rs747727055, rs876658804, rs780001540, rs760815829, rs878854926, rs775248597, rs886040658, rs886040192, rs786203523, rs886040319, rs397508006, rs587782011, rs1060502772, rs1555461727, rs1553333072, rs1114167702, rs1257401983, rs886040950, rs1060502759, rs774684620, rs142947311, rs1555580883, rs748513310, rs376170600, rs863224499, rs1593909229, rs748453607, rs1294578913, rs1574737047, rs1593909960, rs2081922847, rs2082559544, rs2053694038 24493630, 29059683

| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412