DBN1 (drebrin 1)

Gene

• Entrez ID: 1627
• Gene name: Drebrin 1
• Gene symbol: DBN1
• Synonyms: D0S117E
• Chromosome: 5
• Chromosome location: 5q35.3
• Summary: The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020934	hsa-miR-155-5p	Proteomics	18668040
MIRT024053	hsa-miR-1-3p	Proteomics	18668040
MIRT024053	hsa-miR-1-3p	Proteomics;Microarray	18668037
MIRT046733	hsa-miR-222-3p	CLASH	23622248
MIRT045543	hsa-miR-149-5p	CLASH	23622248
MIRT045157	hsa-miR-186-5p	CLASH	23622248
MIRT040871	hsa-miR-18a-3p	CLASH	23622248
MIRT039919	hsa-miR-615-3p	CLASH	23622248
MIRT037119	hsa-miR-877-3p	CLASH	23622248
MIRT558490	hsa-miR-137	HITS-CLIP	21572407
MIRT558488	hsa-miR-4282	HITS-CLIP	21572407
MIRT558489	hsa-miR-10a-3p	HITS-CLIP	21572407
MIRT558486	hsa-miR-4307	HITS-CLIP	21572407
MIRT558487	hsa-miR-4729	HITS-CLIP	21572407
MIRT558485	hsa-miR-4716-5p	HITS-CLIP	21572407
MIRT558484	hsa-miR-4536-3p	HITS-CLIP	21572407
MIRT558478	hsa-miR-517a-3p	HITS-CLIP	21572407
MIRT558477	hsa-miR-517b-3p	HITS-CLIP	21572407
MIRT558476	hsa-miR-517c-3p	HITS-CLIP	21572407
MIRT558473	hsa-miR-5590-5p	HITS-CLIP	21572407
MIRT558474	hsa-miR-4659a-5p	HITS-CLIP	21572407
MIRT558472	hsa-miR-4659b-5p	HITS-CLIP	21572407
MIRT558471	hsa-miR-4776-3p	HITS-CLIP	21572407
MIRT558492	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT558491	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT558490	hsa-miR-137	PAR-CLIP	21572407
MIRT558488	hsa-miR-4282	PAR-CLIP	21572407
MIRT558489	hsa-miR-10a-3p	PAR-CLIP	21572407
MIRT558486	hsa-miR-4307	PAR-CLIP	21572407
MIRT558487	hsa-miR-4729	PAR-CLIP	21572407
MIRT558485	hsa-miR-4716-5p	PAR-CLIP	21572407
MIRT558484	hsa-miR-4536-3p	PAR-CLIP	21572407
MIRT558483	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT558482	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT558481	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT558480	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT558479	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT558478	hsa-miR-517a-3p	PAR-CLIP	21572407
MIRT558477	hsa-miR-517b-3p	PAR-CLIP	21572407
MIRT558476	hsa-miR-517c-3p	PAR-CLIP	21572407
MIRT558475	hsa-miR-548aw	PAR-CLIP	21572407
MIRT558473	hsa-miR-5590-5p	PAR-CLIP	21572407
MIRT558474	hsa-miR-4659a-5p	PAR-CLIP	21572407
MIRT558472	hsa-miR-4659b-5p	PAR-CLIP	21572407
MIRT558471	hsa-miR-4776-3p	PAR-CLIP	21572407
MIRT538201	hsa-miR-483-3p	PAR-CLIP	22012620
MIRT538200	hsa-miR-5195-5p	PAR-CLIP	22012620
MIRT538199	hsa-miR-5193	PAR-CLIP	22012620
MIRT538198	hsa-miR-660-3p	PAR-CLIP	22012620
MIRT538197	hsa-miR-1914-5p	PAR-CLIP	22012620
MIRT538196	hsa-miR-1304-3p	PAR-CLIP	22012620
MIRT538195	hsa-miR-4679	PAR-CLIP	22012620
MIRT538194	hsa-miR-548ao-5p	PAR-CLIP	22012620
MIRT538193	hsa-miR-548ax	PAR-CLIP	22012620
MIRT538192	hsa-miR-5585-5p	PAR-CLIP	22012620
MIRT538191	hsa-miR-4513	PAR-CLIP	22012620
MIRT538190	hsa-miR-6855-3p	PAR-CLIP	22012620
MIRT538189	hsa-miR-6857-3p	PAR-CLIP	22012620
MIRT538188	hsa-miR-653-3p	PAR-CLIP	22012620
MIRT538187	hsa-miR-3136-5p	PAR-CLIP	22012620
MIRT538186	hsa-miR-4439	PAR-CLIP	22012620
MIRT538185	hsa-miR-943	PAR-CLIP	22012620
MIRT538184	hsa-miR-8070	PAR-CLIP	22012620
MIRT538183	hsa-miR-4675	PAR-CLIP	22012620
MIRT558490	hsa-miR-137	HITS-CLIP	21572407
MIRT558488	hsa-miR-4282	HITS-CLIP	21572407
MIRT558489	hsa-miR-10a-3p	HITS-CLIP	21572407
MIRT558486	hsa-miR-4307	HITS-CLIP	21572407
MIRT558487	hsa-miR-4729	HITS-CLIP	21572407
MIRT558485	hsa-miR-4716-5p	HITS-CLIP	21572407
MIRT558484	hsa-miR-4536-3p	HITS-CLIP	21572407
MIRT558478	hsa-miR-517a-3p	HITS-CLIP	21572407
MIRT558477	hsa-miR-517b-3p	HITS-CLIP	21572407
MIRT558476	hsa-miR-517c-3p	HITS-CLIP	21572407
MIRT558473	hsa-miR-5590-5p	HITS-CLIP	21572407
MIRT558474	hsa-miR-4659a-5p	HITS-CLIP	21572407
MIRT558472	hsa-miR-4659b-5p	HITS-CLIP	21572407
MIRT558471	hsa-miR-4776-3p	HITS-CLIP	21572407
MIRT558492	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT558491	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT558490	hsa-miR-137	PAR-CLIP	21572407
MIRT558488	hsa-miR-4282	PAR-CLIP	21572407
MIRT558489	hsa-miR-10a-3p	PAR-CLIP	21572407
MIRT558486	hsa-miR-4307	PAR-CLIP	21572407
MIRT558487	hsa-miR-4729	PAR-CLIP	21572407
MIRT558485	hsa-miR-4716-5p	PAR-CLIP	21572407
MIRT558484	hsa-miR-4536-3p	PAR-CLIP	21572407
MIRT558483	hsa-miR-548aj-5p	PAR-CLIP	21572407
MIRT558482	hsa-miR-548f-5p	PAR-CLIP	21572407
MIRT558481	hsa-miR-548g-5p	PAR-CLIP	21572407
MIRT558480	hsa-miR-548x-5p	PAR-CLIP	21572407
MIRT558479	hsa-miR-1468-3p	PAR-CLIP	21572407
MIRT558478	hsa-miR-517a-3p	PAR-CLIP	21572407
MIRT558477	hsa-miR-517b-3p	PAR-CLIP	21572407
MIRT558476	hsa-miR-517c-3p	PAR-CLIP	21572407
MIRT558475	hsa-miR-548aw	PAR-CLIP	21572407
MIRT558473	hsa-miR-5590-5p	PAR-CLIP	21572407
MIRT558474	hsa-miR-4659a-5p	PAR-CLIP	21572407
MIRT558472	hsa-miR-4659b-5p	PAR-CLIP	21572407
MIRT558471	hsa-miR-4776-3p	PAR-CLIP	21572407
MIRT538201	hsa-miR-483-3p	PAR-CLIP	22012620
MIRT538200	hsa-miR-5195-5p	PAR-CLIP	22012620
MIRT538199	hsa-miR-5193	PAR-CLIP	22012620
MIRT538198	hsa-miR-660-3p	PAR-CLIP	22012620
MIRT538197	hsa-miR-1914-5p	PAR-CLIP	22012620
MIRT538196	hsa-miR-1304-3p	PAR-CLIP	22012620
MIRT538195	hsa-miR-4679	PAR-CLIP	22012620
MIRT538194	hsa-miR-548ao-5p	PAR-CLIP	22012620
MIRT538193	hsa-miR-548ax	PAR-CLIP	22012620
MIRT538192	hsa-miR-5585-5p	PAR-CLIP	22012620
MIRT538191	hsa-miR-4513	PAR-CLIP	22012620
MIRT538190	hsa-miR-6855-3p	PAR-CLIP	22012620
MIRT538189	hsa-miR-6857-3p	PAR-CLIP	22012620
MIRT538188	hsa-miR-653-3p	PAR-CLIP	22012620
MIRT538187	hsa-miR-3136-5p	PAR-CLIP	22012620
MIRT538186	hsa-miR-4439	PAR-CLIP	22012620
MIRT538185	hsa-miR-943	PAR-CLIP	22012620
MIRT538184	hsa-miR-8070	PAR-CLIP	22012620
MIRT538183	hsa-miR-4675	PAR-CLIP	22012620
MIRT923758	hsa-miR-103b	CLIP-seq
MIRT923759	hsa-miR-1203	CLIP-seq
MIRT923760	hsa-miR-1207-3p	CLIP-seq
MIRT923761	hsa-miR-1224-3p	CLIP-seq
MIRT923762	hsa-miR-1260	CLIP-seq
MIRT923763	hsa-miR-1260b	CLIP-seq
MIRT923764	hsa-miR-1275	CLIP-seq
MIRT923765	hsa-miR-1280	CLIP-seq
MIRT923766	hsa-miR-1290	CLIP-seq
MIRT923767	hsa-miR-1291	CLIP-seq
MIRT923768	hsa-miR-129-3p	CLIP-seq
MIRT923769	hsa-miR-146b-3p	CLIP-seq
MIRT923770	hsa-miR-182	CLIP-seq
MIRT923771	hsa-miR-188-3p	CLIP-seq
MIRT923772	hsa-miR-1908	CLIP-seq
MIRT923773	hsa-miR-1915	CLIP-seq
MIRT923774	hsa-miR-1972	CLIP-seq
MIRT923775	hsa-miR-19a	CLIP-seq
MIRT923776	hsa-miR-19b	CLIP-seq
MIRT923777	hsa-miR-2110	CLIP-seq
MIRT923778	hsa-miR-2113	CLIP-seq
MIRT923779	hsa-miR-2355-5p	CLIP-seq
MIRT923780	hsa-miR-2861	CLIP-seq
MIRT923781	hsa-miR-296-5p	CLIP-seq
MIRT923782	hsa-miR-31	CLIP-seq
MIRT923783	hsa-miR-3121-5p	CLIP-seq
MIRT923784	hsa-miR-3123	CLIP-seq
MIRT923785	hsa-miR-3132	CLIP-seq
MIRT923786	hsa-miR-3141	CLIP-seq
MIRT923787	hsa-miR-3145-3p	CLIP-seq
MIRT923788	hsa-miR-3150a-3p	CLIP-seq
MIRT923789	hsa-miR-3154	CLIP-seq
MIRT923790	hsa-miR-3156-3p	CLIP-seq
MIRT923791	hsa-miR-3167	CLIP-seq
MIRT923792	hsa-miR-3173-3p	CLIP-seq
MIRT923793	hsa-miR-3175	CLIP-seq
MIRT923794	hsa-miR-3176	CLIP-seq
MIRT923795	hsa-miR-3177-3p	CLIP-seq
MIRT923796	hsa-miR-3184	CLIP-seq
MIRT923797	hsa-miR-3189-5p	CLIP-seq
MIRT923798	hsa-miR-3200-5p	CLIP-seq
MIRT923799	hsa-miR-320a	CLIP-seq
MIRT923800	hsa-miR-320b	CLIP-seq
MIRT923801	hsa-miR-320c	CLIP-seq
MIRT923802	hsa-miR-320d	CLIP-seq
MIRT923803	hsa-miR-331-3p	CLIP-seq
MIRT923804	hsa-miR-3607-3p	CLIP-seq
MIRT923805	hsa-miR-3609	CLIP-seq
MIRT923806	hsa-miR-3619-3p	CLIP-seq
MIRT923807	hsa-miR-3622a-5p	CLIP-seq
MIRT923808	hsa-miR-3651	CLIP-seq
MIRT923809	hsa-miR-3661	CLIP-seq
MIRT923810	hsa-miR-3663-3p	CLIP-seq
MIRT923811	hsa-miR-3665	CLIP-seq
MIRT923812	hsa-miR-3689a-5p	CLIP-seq
MIRT923813	hsa-miR-3689b	CLIP-seq
MIRT923814	hsa-miR-3689e	CLIP-seq
MIRT923815	hsa-miR-3689f	CLIP-seq
MIRT923816	hsa-miR-3690	CLIP-seq
MIRT923817	hsa-miR-3691-3p	CLIP-seq
MIRT923818	hsa-miR-378	CLIP-seq
MIRT923819	hsa-miR-378b	CLIP-seq
MIRT923820	hsa-miR-378c	CLIP-seq
MIRT923821	hsa-miR-378d	CLIP-seq
MIRT923822	hsa-miR-378e	CLIP-seq
MIRT923823	hsa-miR-378f	CLIP-seq
MIRT923824	hsa-miR-378h	CLIP-seq
MIRT923825	hsa-miR-378i	CLIP-seq
MIRT923826	hsa-miR-3918	CLIP-seq
MIRT923827	hsa-miR-3919	CLIP-seq
MIRT923828	hsa-miR-3922-3p	CLIP-seq
MIRT923829	hsa-miR-3929	CLIP-seq
MIRT923830	hsa-miR-3937	CLIP-seq
MIRT923831	hsa-miR-422a	CLIP-seq
MIRT923832	hsa-miR-423-5p	CLIP-seq
MIRT923833	hsa-miR-4259	CLIP-seq
MIRT923834	hsa-miR-4269	CLIP-seq
MIRT923835	hsa-miR-4270	CLIP-seq
MIRT923836	hsa-miR-4292	CLIP-seq
MIRT923837	hsa-miR-4308	CLIP-seq
MIRT923838	hsa-miR-4311	CLIP-seq
MIRT923839	hsa-miR-4316	CLIP-seq
MIRT923840	hsa-miR-4419b	CLIP-seq
MIRT923841	hsa-miR-4429	CLIP-seq
MIRT923842	hsa-miR-4435	CLIP-seq
MIRT923843	hsa-miR-4441	CLIP-seq
MIRT923844	hsa-miR-4446-5p	CLIP-seq
MIRT923845	hsa-miR-4447	CLIP-seq
MIRT923846	hsa-miR-4472	CLIP-seq
MIRT923847	hsa-miR-4477a	CLIP-seq
MIRT923848	hsa-miR-4478	CLIP-seq
MIRT923849	hsa-miR-4480	CLIP-seq
MIRT923850	hsa-miR-4481	CLIP-seq
MIRT923851	hsa-miR-4496	CLIP-seq
MIRT923852	hsa-miR-450b-5p	CLIP-seq
MIRT923853	hsa-miR-4520a-3p	CLIP-seq
MIRT923854	hsa-miR-4525	CLIP-seq
MIRT923855	hsa-miR-4638-3p	CLIP-seq
MIRT923856	hsa-miR-4640-5p	CLIP-seq
MIRT923857	hsa-miR-4650-5p	CLIP-seq
MIRT923858	hsa-miR-4651	CLIP-seq
MIRT923859	hsa-miR-4665-5p	CLIP-seq
MIRT923860	hsa-miR-4685-5p	CLIP-seq
MIRT923861	hsa-miR-4687-5p	CLIP-seq
MIRT923862	hsa-miR-4706	CLIP-seq
MIRT923863	hsa-miR-4710	CLIP-seq
MIRT923864	hsa-miR-4722-5p	CLIP-seq
MIRT923865	hsa-miR-4723-5p	CLIP-seq
MIRT923866	hsa-miR-4726-3p	CLIP-seq
MIRT923867	hsa-miR-4726-5p	CLIP-seq
MIRT923868	hsa-miR-4728-5p	CLIP-seq
MIRT923869	hsa-miR-4732-3p	CLIP-seq
MIRT923870	hsa-miR-4743	CLIP-seq
MIRT923871	hsa-miR-4745-5p	CLIP-seq
MIRT923872	hsa-miR-4747-5p	CLIP-seq
MIRT923873	hsa-miR-4749-5p	CLIP-seq
MIRT923874	hsa-miR-4755-3p	CLIP-seq
MIRT923875	hsa-miR-4759	CLIP-seq
MIRT923876	hsa-miR-4768-3p	CLIP-seq
MIRT923877	hsa-miR-4776-5p	CLIP-seq
MIRT923878	hsa-miR-4779	CLIP-seq
MIRT923879	hsa-miR-4786-3p	CLIP-seq
MIRT923880	hsa-miR-4803	CLIP-seq
MIRT923881	hsa-miR-483-5p	CLIP-seq
MIRT923882	hsa-miR-485-5p	CLIP-seq
MIRT923883	hsa-miR-494	CLIP-seq
MIRT923884	hsa-miR-517a	CLIP-seq
MIRT923885	hsa-miR-517b	CLIP-seq
MIRT923886	hsa-miR-517c	CLIP-seq
MIRT923887	hsa-miR-520d-5p	CLIP-seq
MIRT923888	hsa-miR-520g	CLIP-seq
MIRT923889	hsa-miR-520h	CLIP-seq
MIRT923890	hsa-miR-524-5p	CLIP-seq
MIRT923891	hsa-miR-541	CLIP-seq
MIRT923892	hsa-miR-548a-3p	CLIP-seq
MIRT923893	hsa-miR-548ah	CLIP-seq
MIRT923894	hsa-miR-548e	CLIP-seq
MIRT923895	hsa-miR-548f	CLIP-seq
MIRT923896	hsa-miR-548n	CLIP-seq
MIRT923897	hsa-miR-548t	CLIP-seq
MIRT923898	hsa-miR-558	CLIP-seq
MIRT923899	hsa-miR-564	CLIP-seq
MIRT923900	hsa-miR-571	CLIP-seq
MIRT923901	hsa-miR-608	CLIP-seq
MIRT923902	hsa-miR-615-5p	CLIP-seq
MIRT923903	hsa-miR-625	CLIP-seq
MIRT923904	hsa-miR-631	CLIP-seq
MIRT923905	hsa-miR-654-5p	CLIP-seq
MIRT923906	hsa-miR-657	CLIP-seq
MIRT923907	hsa-miR-663	CLIP-seq
MIRT923908	hsa-miR-876-5p	CLIP-seq
MIRT923909	hsa-miR-935	CLIP-seq
MIRT923910	hsa-miR-939	CLIP-seq
MIRT923794	hsa-miR-3176	CLIP-seq
MIRT923795	hsa-miR-3177-3p	CLIP-seq
MIRT923807	hsa-miR-3622a-5p	CLIP-seq
MIRT923811	hsa-miR-3665	CLIP-seq
MIRT923828	hsa-miR-3922-3p	CLIP-seq
MIRT923829	hsa-miR-3929	CLIP-seq
MIRT923834	hsa-miR-4269	CLIP-seq
MIRT923840	hsa-miR-4419b	CLIP-seq
MIRT923842	hsa-miR-4435	CLIP-seq
MIRT923848	hsa-miR-4478	CLIP-seq
MIRT923882	hsa-miR-485-5p	CLIP-seq
MIRT923891	hsa-miR-541	CLIP-seq
MIRT923899	hsa-miR-564	CLIP-seq
MIRT923905	hsa-miR-654-5p	CLIP-seq
MIRT923906	hsa-miR-657	CLIP-seq
MIRT923773	hsa-miR-1915	CLIP-seq
MIRT923835	hsa-miR-4270	CLIP-seq
MIRT923843	hsa-miR-4441	CLIP-seq
MIRT923866	hsa-miR-4726-3p	CLIP-seq
MIRT923902	hsa-miR-615-5p	CLIP-seq
MIRT923759	hsa-miR-1203	CLIP-seq
MIRT923767	hsa-miR-1291	CLIP-seq
MIRT923769	hsa-miR-146b-3p	CLIP-seq
MIRT923774	hsa-miR-1972	CLIP-seq
MIRT923779	hsa-miR-2355-5p	CLIP-seq
MIRT923785	hsa-miR-3132	CLIP-seq
MIRT923792	hsa-miR-3173-3p	CLIP-seq
MIRT923794	hsa-miR-3176	CLIP-seq
MIRT923795	hsa-miR-3177-3p	CLIP-seq
MIRT923806	hsa-miR-3619-3p	CLIP-seq
MIRT923807	hsa-miR-3622a-5p	CLIP-seq
MIRT923810	hsa-miR-3663-3p	CLIP-seq
MIRT923811	hsa-miR-3665	CLIP-seq
MIRT923817	hsa-miR-3691-3p	CLIP-seq
MIRT923818	hsa-miR-378	CLIP-seq
MIRT923819	hsa-miR-378b	CLIP-seq
MIRT923820	hsa-miR-378c	CLIP-seq
MIRT923821	hsa-miR-378d	CLIP-seq
MIRT923822	hsa-miR-378e	CLIP-seq
MIRT923823	hsa-miR-378f	CLIP-seq
MIRT923824	hsa-miR-378h	CLIP-seq
MIRT923825	hsa-miR-378i	CLIP-seq
MIRT923826	hsa-miR-3918	CLIP-seq
MIRT923828	hsa-miR-3922-3p	CLIP-seq
MIRT923829	hsa-miR-3929	CLIP-seq
MIRT923830	hsa-miR-3937	CLIP-seq
MIRT923831	hsa-miR-422a	CLIP-seq
MIRT923834	hsa-miR-4269	CLIP-seq
MIRT923835	hsa-miR-4270	CLIP-seq
MIRT923839	hsa-miR-4316	CLIP-seq
MIRT923840	hsa-miR-4419b	CLIP-seq
MIRT923842	hsa-miR-4435	CLIP-seq
MIRT923843	hsa-miR-4441	CLIP-seq
MIRT2209200	hsa-miR-4468	CLIP-seq
MIRT923848	hsa-miR-4478	CLIP-seq
MIRT923849	hsa-miR-4480	CLIP-seq
MIRT923850	hsa-miR-4481	CLIP-seq
MIRT923852	hsa-miR-450b-5p	CLIP-seq
MIRT923855	hsa-miR-4638-3p	CLIP-seq
MIRT923857	hsa-miR-4650-5p	CLIP-seq
MIRT2209201	hsa-miR-4663	CLIP-seq
MIRT923860	hsa-miR-4685-5p	CLIP-seq
MIRT923863	hsa-miR-4710	CLIP-seq
MIRT923868	hsa-miR-4728-5p	CLIP-seq
MIRT923870	hsa-miR-4743	CLIP-seq
MIRT923871	hsa-miR-4745-5p	CLIP-seq
MIRT923872	hsa-miR-4747-5p	CLIP-seq
MIRT923874	hsa-miR-4755-3p	CLIP-seq
MIRT923877	hsa-miR-4776-5p	CLIP-seq
MIRT923878	hsa-miR-4779	CLIP-seq
MIRT923882	hsa-miR-485-5p	CLIP-seq
MIRT923898	hsa-miR-558	CLIP-seq
MIRT923899	hsa-miR-564	CLIP-seq
MIRT923906	hsa-miR-657	CLIP-seq
MIRT2209202	hsa-miR-941	CLIP-seq
MIRT2386733	hsa-miR-1324	CLIP-seq
MIRT923783	hsa-miR-3121-5p	CLIP-seq
MIRT923856	hsa-miR-4640-5p	CLIP-seq
MIRT923867	hsa-miR-4726-5p	CLIP-seq
MIRT923760	hsa-miR-1207-3p	CLIP-seq
MIRT923780	hsa-miR-2861	CLIP-seq
MIRT923781	hsa-miR-296-5p	CLIP-seq
MIRT923796	hsa-miR-3184	CLIP-seq
MIRT923832	hsa-miR-423-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001701	Process	In utero embryonic development	IEA
GO:0003779	Function	Actin binding	NAS	12761245
GO:0005515	Function	Protein binding	IPI	12577067, 20215400, 21044950, 23750010, 23926103, 23940795, 25814554, 25839164, 28966017
GO:0005522	Function	Profilin binding	ISS
GO:0005737	Component	Cytoplasm	IDA	8838578, 28966017
GO:0005737	Component	Cytoplasm	NAS	12009525
GO:0005856	Component	Cytoskeleton	IDA	24327345
GO:0005884	Component	Actin filament	IBA	21873635
GO:0005886	Component	Plasma membrane	IBA	21873635
GO:0005921	Component	Gap junction	IEA
GO:0007015	Process	Actin filament organization	ISS
GO:0010643	Process	Cell communication by chemical coupling	IEA
GO:0010644	Process	Cell communication by electrical coupling	IEA
GO:0014069	Component	Postsynaptic density	IBA	21873635
GO:0015629	Component	Actin cytoskeleton	ISS
GO:0030027	Component	Lamellipodium	IBA	21873635
GO:0030425	Component	Dendrite	IBA	21873635
GO:0030425	Component	Dendrite	IDA	8838578
GO:0030425	Component	Dendrite	NAS	12009525
GO:0030426	Component	Growth cone	ISS
GO:0030427	Component	Site of polarized growth	IBA	21873635
GO:0030833	Process	Regulation of actin filament polymerization	IBA	21873635
GO:0030863	Component	Cortical cytoskeleton	TAS	17251419
GO:0030864	Component	Cortical actin cytoskeleton	IBA	21873635
GO:0031915	Process	Positive regulation of synaptic plasticity	ISS
GO:0032507	Process	Maintenance of protein location in cell	IEA
GO:0042641	Component	Actomyosin	NAS	12761245
GO:0045211	Component	Postsynaptic membrane	IBA	21873635
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0045773	Process	Positive regulation of axon extension	IBA	21873635
GO:0048168	Process	Regulation of neuronal synaptic plasticity	NAS	12009525
GO:0048812	Process	Neuron projection morphogenesis	IBA	21873635
GO:0050773	Process	Regulation of dendrite development	NAS	12009525
GO:0051015	Function	Actin filament binding	IBA	21873635
GO:0051220	Process	Cytoplasmic sequestering of protein	IDA	28966017
GO:0061003	Process	Positive regulation of dendritic spine morphogenesis	IBA	21873635
GO:0061003	Process	Positive regulation of dendritic spine morphogenesis	ISS
GO:0061351	Process	Neural precursor cell proliferation	IEA
GO:0098974	Process	Postsynaptic actin cytoskeleton organization	IBA	21873635
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0099524	Component	Postsynaptic cytosol	IEA
GO:1902685	Process	Positive regulation of receptor localization to synapse	ISS

Other IDs

• MIM: 126660
• HGNC: 2695
• e!Ensembl: ENSG00000113758

Protein

• UniProt ID: Q16643
• Protein name: Drebrin (Developmentally-regulated brain protein)
• Protein function: Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (PubMed:20215400). Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS (PubMe
• PDB: 5Y1Z, 5ZZ9
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00241	Cofilin_ADF	13 → 132	Cofilin/tropomyosin-type actin-binding protein	Domain

• Sequence:

  MAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFEN
  QKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASS
  VEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQF
  WEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQ
  TLEAEEAKRRLKEQSIFGDHRDEEEETHMKKSESEVEEAAAIIAQRPDNPREFFKQQERV
  ASASAGSCDVPSPFNHRPGSHLDSHRRMAPTPIPTRSPSDSSTASTPVAEQIERALDEVT
  SSQPPPLPPPPPPAQETQEPSPILDSEETRAAAPQAWAGPMEEPPQAQAPPRGPGSPAED
  LMFMESAEQAVLAAPVEPATADATEIHDAADTIETDTATADTTVANNVPPAATSLIDLWP
  GNGEGASTLQGEPRAPTPPSGTEVTLAEVPLLDEVAPEPLLPAGEGCATLLNFDELPEPP
  ATFCDPEEVEGESLAAPQTPTLPSALEELEQEQEPEPHLLTNGETTQKEGTQASEGYFSQ
  SQEEEFAQSEELCAKAPPPVFYNKPPEIDITCWDADPVPEEEEGFEGGD

• Sequence length: 649

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158, rs80357524, rs80357115, rs80357945, rs80357729, rs80357609, rs80357259, rs80357981, rs80358063, rs80357389, rs80356862, rs80359876, rs80357580, rs80358053, rs80358089, rs80187739, rs397507241, rs80358069, rs80357590, rs80357284, rs80357941, rs80359261, rs80359272, rs80359276, rs276174813, rs80358474, rs80359316, rs1555282969, rs80359388, rs80359499, rs80359505, rs80359520, rs80359526, rs80359533, rs56253082, rs80358824, rs80359554, rs80359636, rs80359651, rs80359659, rs80359011, rs80359012, rs80359013, rs80359718, rs397507410, rs81002812, rs80359730, rs80359152, rs80359159, rs397507419, rs28897759, rs80359211, rs80359775, rs397514577, rs397507584, rs80358435, rs80358456, rs80359340, rs80359343, rs80359365, rs80358579, rs397507670, rs80358593, rs80359406, rs80359444, rs80359454, rs276174853, rs276174854, rs80359483, rs80359537, rs80358815, rs80358843, rs80359558, rs80359560, rs80359594, rs80358893, rs28897743, rs397507900, rs397507906, rs397507918, rs80358971, rs80358981, rs397507941, rs80359030, rs80359035, rs41293511, rs397507396, rs81002806, rs80359112, rs397508006, rs81002893, rs45580035, rs80359760, rs397508051, rs80359772, rs4987049, rs80359777, rs80357770, rs397508867, rs62625303, rs397508874, rs80357506, rs80357287, rs273898674, rs80358042, rs80358083, rs80357058, rs41286296, rs80357960, rs80356945, rs80357223, rs386134270, rs80358116, rs80357856, rs80357424, rs397509050, rs80357485, rs80357966, rs397509067, rs80357310, rs80356866, rs80357260, rs80357437, rs80358023, rs80358086, rs80357133, rs80356993, rs80357997, rs80357239, rs80357227, rs397509243, rs80356969, rs80356959, rs63750617, rs63751319, rs587779315, rs200640585, rs398122546, rs80357543, rs398122687, rs80359328, rs398122779, rs398122783, rs62517194, rs80358029, rs515726060, rs180177103, rs180177111, rs180177133, rs587776527, rs180177135, rs180177136, rs515726117, rs587779813, rs587779909, rs587780024, rs587780100, rs28909982, rs121908698, rs180177100, rs587780210, rs587780240, rs587780639, rs587781269, rs587781353, rs587781471, rs587781658, rs587781697, rs587781730, rs587781894, rs587781948, rs587782005, rs587782011, rs200928781, rs587781558, rs370228071, rs587782245, rs587782401, rs180177110, rs587782504, rs72552322, rs587782531, rs587782620, rs587782680, rs587782774, rs587782818, rs730881411, rs730881389, rs564652222, rs397507768, rs587776419, rs730881868, rs730881940, rs56383036, rs758972589, rs201089102, rs730881348, rs786202608, rs786201886, rs786203318, rs786203775, rs786203714, rs786202033, rs750621215, rs786203884, rs786203650, rs772821016, rs863224521, rs864622223, rs864622655, rs375699023, rs876659572, rs768362387, rs876659535, rs876658957, rs483353072, rs876659435, rs267608041, rs876661113, rs730881369, rs878853535, rs772228129, rs878855122, rs760551339, rs80359596, rs397509222, rs886039630, rs886039683, rs886040828, rs587781799, rs886040374, rs886040649, rs397507967, rs878854957, rs886040043, rs1057517589, rs1060502769, rs866380588, rs863224765, rs1064793243, rs747563556, rs1555074976, rs1064795885, rs753961188, rs1064794708, rs869312772, rs1064793887, rs1131690820, rs1135401928, rs1135401868, rs1135401859, rs1553370324, rs397507630, rs1555283160, rs1555283251, rs1555283262, rs1555283361, rs1555286298, rs1555288462, rs886040950, rs1555289566, rs776323117, rs80357123, rs1555579627, rs1555580697, rs80358054, rs1555593302, rs1328985852, rs763470424, rs1555139694, rs878854697, rs1555461217, rs1555461765, rs774684620, rs766416564, rs1554558613, rs1305740166, rs1555461460, rs1555461407, rs1555461586, rs1555567202, rs1555607022, rs1555069815, rs1442299125, rs1474786480, rs1555084947, rs1555457867, rs141087784, rs1482641121, rs1564830522, rs1565469955, rs1565503137, rs864622613, rs755263466, rs757679199, rs1593903166, rs1597801649, rs1603293306, rs879253880, rs80358754, rs1597062038, rs45494092, rs1603275367, rs887358871, rs1597091518, rs1966967065, rs1064793049, rs2082872908, rs2085078278, rs2072475243
Schizophrenia	Schizophrenia	rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313	15140563, 16402129, 23566496

Unknown
Disease name	Disease term	dbSNP ID	References
Bipolar disorder	Bipolar Disorder		22760556