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TMEM30B (transmembrane protein 30B)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
161291
Gene nameGene Name - the full gene name approved by the HGNC.
Transmembrane protein 30B
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
TMEM30B
SynonymsGene synonyms aliases
CDC50B
ChromosomeChromosome number
14
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
14q23.1
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT018891 hsa-miR-335-5p Microarray 18185580
MIRT030135 hsa-miR-26b-5p Microarray 19088304
MIRT625099 hsa-miR-34b-3p HITS-CLIP 22927820
MIRT609232 hsa-miR-8485 HITS-CLIP 22927820
MIRT625098 hsa-miR-377-3p HITS-CLIP 22927820
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 20947505, 21914794, 32296183
GO:0005783 Component Endoplasmic reticulum IBA 21873635
GO:0005794 Component Golgi apparatus IBA 21873635
GO:0005886 Component Plasma membrane IBA 21873635
GO:0015247 Function Aminophospholipid flippase activity IDA 20510206
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q3MIR4
Protein name Cell cycle control protein 50B (P4-ATPase flippase complex beta subunit TMEM30B) (Transmembrane protein 30B)
Protein function Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribut
PDB 7VGH
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03381 CDC50
53 345
LEM3 (ligand-effect modulator 3) family / CDC50 family
Family
Sequence
Sequence length 351
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
  Efferocytosis  
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Melanoma melanoma rs121913315, rs121913323, rs137853080, rs137853081, rs121909232, rs121913388, rs104894094, rs1563902635, rs104894095, rs104894097, rs104894098, rs104894099, rs104894109, rs137854599, rs11547328, rs104894340, rs398123152, rs587780668, rs587782083, rs587782206, rs587782792, rs180177042, rs121913381, rs730881675, rs730881674, rs730881677, rs730881673, rs1800586, rs768966657, rs587778189, rs786204195, rs121913321, rs45476696, rs864622636, rs864622263, rs869025340, rs876660436, rs876658534, rs876658556, rs878853647, rs878853644, rs878853650, rs886041162, rs121913389, rs1057519852, rs121913384, rs121913387, rs1060501266, rs1060501263, rs1060501262, rs749714198, rs1060501265, rs559848002, rs1064794292, rs1131691187, rs1131691186, rs199907548, rs1554654052, rs1554656411, rs1554656624, rs1554653915, rs1554653956, rs1554656253, rs1554654224, rs754806883, rs1057520039, rs1563889584, rs1563889685, rs1287464120, rs1563888944, rs1563892715, rs1563889847, rs141798398, rs1587332338, rs1587340291, rs11552823, rs561034503, rs138677674, rs1819962958, rs1820531050 16778180

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