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AMZ1 (archaelysin family metallopeptidase 1)

Gene

155185

Archaelysin family metallopeptidase 1

AMZ1

7p22.3

Show/Hide all(237)

miRTarBase ID	miRNA	Experiments	Reference
MIRT023825	hsa-miR-1-3p	Microarray	18668037
MIRT045029	hsa-miR-186-5p	CLASH	23622248
MIRT710951	hsa-miR-1470	HITS-CLIP	19536157
MIRT710950	hsa-miR-4667-3p	HITS-CLIP	19536157
MIRT710949	hsa-miR-5193	HITS-CLIP	19536157
MIRT710947	hsa-miR-4304	HITS-CLIP	19536157
MIRT710948	hsa-miR-4469	HITS-CLIP	19536157
MIRT710946	hsa-miR-324-5p	HITS-CLIP	19536157
MIRT710951	hsa-miR-1470	HITS-CLIP	19536157
MIRT710950	hsa-miR-4667-3p	HITS-CLIP	19536157
MIRT710949	hsa-miR-5193	HITS-CLIP	19536157
MIRT710947	hsa-miR-4304	HITS-CLIP	19536157
MIRT710948	hsa-miR-4469	HITS-CLIP	19536157
MIRT710946	hsa-miR-324-5p	HITS-CLIP	19536157
MIRT710951	hsa-miR-1470	HITS-CLIP	19536157
MIRT710950	hsa-miR-4667-3p	HITS-CLIP	19536157
MIRT710949	hsa-miR-5193	HITS-CLIP	19536157
MIRT710947	hsa-miR-4304	HITS-CLIP	19536157
MIRT710948	hsa-miR-4469	HITS-CLIP	19536157
MIRT710946	hsa-miR-324-5p	HITS-CLIP	19536157
MIRT710951	hsa-miR-1470	HITS-CLIP	19536157
MIRT710950	hsa-miR-4667-3p	HITS-CLIP	19536157
MIRT710949	hsa-miR-5193	HITS-CLIP	19536157
MIRT710947	hsa-miR-4304	HITS-CLIP	19536157
MIRT710948	hsa-miR-4469	HITS-CLIP	19536157
MIRT710946	hsa-miR-324-5p	HITS-CLIP	19536157
MIRT614379	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT614378	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT614377	hsa-miR-4514	HITS-CLIP	23824327
MIRT614376	hsa-miR-4692	HITS-CLIP	23824327
MIRT614375	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT614374	hsa-miR-4673	HITS-CLIP	23824327
MIRT614373	hsa-miR-877-3p	HITS-CLIP	23824327
MIRT614372	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT614371	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT614370	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT710951	hsa-miR-1470	HITS-CLIP	19536157
MIRT710950	hsa-miR-4667-3p	HITS-CLIP	19536157
MIRT710949	hsa-miR-5193	HITS-CLIP	19536157
MIRT710947	hsa-miR-4304	HITS-CLIP	19536157
MIRT710948	hsa-miR-4469	HITS-CLIP	19536157
MIRT710946	hsa-miR-324-5p	HITS-CLIP	19536157
MIRT710951	hsa-miR-1470	HITS-CLIP	19536157
MIRT710950	hsa-miR-4667-3p	HITS-CLIP	19536157
MIRT710949	hsa-miR-5193	HITS-CLIP	19536157
MIRT710947	hsa-miR-4304	HITS-CLIP	19536157
MIRT710948	hsa-miR-4469	HITS-CLIP	19536157
MIRT710946	hsa-miR-324-5p	HITS-CLIP	19536157
MIRT710951	hsa-miR-1470	HITS-CLIP	19536157
MIRT710950	hsa-miR-4667-3p	HITS-CLIP	19536157
MIRT710949	hsa-miR-5193	HITS-CLIP	19536157
MIRT710947	hsa-miR-4304	HITS-CLIP	19536157
MIRT710948	hsa-miR-4469	HITS-CLIP	19536157
MIRT710946	hsa-miR-324-5p	HITS-CLIP	19536157
MIRT710951	hsa-miR-1470	HITS-CLIP	19536157
MIRT710950	hsa-miR-4667-3p	HITS-CLIP	19536157
MIRT710949	hsa-miR-5193	HITS-CLIP	19536157
MIRT710947	hsa-miR-4304	HITS-CLIP	19536157
MIRT710948	hsa-miR-4469	HITS-CLIP	19536157
MIRT710946	hsa-miR-324-5p	HITS-CLIP	19536157
MIRT614379	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT614378	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT614377	hsa-miR-4514	HITS-CLIP	23824327
MIRT614376	hsa-miR-4692	HITS-CLIP	23824327
MIRT614375	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT614374	hsa-miR-4673	HITS-CLIP	23824327
MIRT614373	hsa-miR-877-3p	HITS-CLIP	23824327
MIRT614372	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT614371	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT614370	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT780673	hsa-miR-1207-5p	CLIP-seq
MIRT780674	hsa-miR-1224-3p	CLIP-seq
MIRT780675	hsa-miR-1229	CLIP-seq
MIRT780676	hsa-miR-1237	CLIP-seq
MIRT780677	hsa-miR-1246	CLIP-seq
MIRT780678	hsa-miR-1255a	CLIP-seq
MIRT780679	hsa-miR-1255b	CLIP-seq
MIRT780680	hsa-miR-1260	CLIP-seq
MIRT780681	hsa-miR-1260b	CLIP-seq
MIRT780682	hsa-miR-1263	CLIP-seq
MIRT780683	hsa-miR-1280	CLIP-seq
MIRT780684	hsa-miR-146b-3p	CLIP-seq
MIRT780685	hsa-miR-155	CLIP-seq
MIRT780686	hsa-miR-1827	CLIP-seq
MIRT780687	hsa-miR-188-5p	CLIP-seq
MIRT780688	hsa-miR-197	CLIP-seq
MIRT780689	hsa-miR-199a-3p	CLIP-seq
MIRT780690	hsa-miR-199b-3p	CLIP-seq
MIRT780691	hsa-miR-2116	CLIP-seq
MIRT780692	hsa-miR-22	CLIP-seq
MIRT780693	hsa-miR-221	CLIP-seq
MIRT780694	hsa-miR-222	CLIP-seq
MIRT780695	hsa-miR-3129-5p	CLIP-seq
MIRT780696	hsa-miR-3154	CLIP-seq
MIRT780697	hsa-miR-3155	CLIP-seq
MIRT780698	hsa-miR-3155b	CLIP-seq
MIRT780699	hsa-miR-3173-5p	CLIP-seq
MIRT780700	hsa-miR-3182	CLIP-seq
MIRT780701	hsa-miR-3200-5p	CLIP-seq
MIRT780702	hsa-miR-3609	CLIP-seq
MIRT780703	hsa-miR-3674	CLIP-seq
MIRT780704	hsa-miR-3677-5p	CLIP-seq
MIRT780705	hsa-miR-3973	CLIP-seq
MIRT780706	hsa-miR-4267	CLIP-seq
MIRT780707	hsa-miR-4292	CLIP-seq
MIRT780708	hsa-miR-4303	CLIP-seq
MIRT780709	hsa-miR-4308	CLIP-seq
MIRT780710	hsa-miR-4311	CLIP-seq
MIRT780711	hsa-miR-4316	CLIP-seq
MIRT780712	hsa-miR-4650-5p	CLIP-seq
MIRT780713	hsa-miR-4652-3p	CLIP-seq
MIRT780714	hsa-miR-4677-3p	CLIP-seq
MIRT780715	hsa-miR-4677-5p	CLIP-seq
MIRT780716	hsa-miR-4679	CLIP-seq
MIRT780717	hsa-miR-4716-5p	CLIP-seq
MIRT780718	hsa-miR-4732-5p	CLIP-seq
MIRT780719	hsa-miR-4736	CLIP-seq
MIRT780720	hsa-miR-4757-5p	CLIP-seq
MIRT780721	hsa-miR-4763-3p	CLIP-seq
MIRT780722	hsa-miR-4786-3p	CLIP-seq
MIRT780723	hsa-miR-484	CLIP-seq
MIRT780724	hsa-miR-493	CLIP-seq
MIRT780725	hsa-miR-5096	CLIP-seq
MIRT780726	hsa-miR-520g	CLIP-seq
MIRT780727	hsa-miR-520h	CLIP-seq
MIRT780728	hsa-miR-532-3p	CLIP-seq
MIRT780729	hsa-miR-548ah	CLIP-seq
MIRT780730	hsa-miR-548v	CLIP-seq
MIRT780731	hsa-miR-645	CLIP-seq
MIRT780732	hsa-miR-766	CLIP-seq
MIRT780733	hsa-miR-874	CLIP-seq
MIRT780734	hsa-miR-890	CLIP-seq
MIRT780735	hsa-miR-936	CLIP-seq
MIRT780736	hsa-miR-942	CLIP-seq
MIRT780676	hsa-miR-1237	CLIP-seq
MIRT780697	hsa-miR-3155	CLIP-seq
MIRT780698	hsa-miR-3155b	CLIP-seq
MIRT780700	hsa-miR-3182	CLIP-seq
MIRT780713	hsa-miR-4652-3p	CLIP-seq
MIRT780723	hsa-miR-484	CLIP-seq
MIRT780725	hsa-miR-5096	CLIP-seq
MIRT780676	hsa-miR-1237	CLIP-seq
MIRT1930451	hsa-miR-1254	CLIP-seq
MIRT1930452	hsa-miR-140-3p	CLIP-seq
MIRT1930453	hsa-miR-148a	CLIP-seq
MIRT1930454	hsa-miR-148b	CLIP-seq
MIRT1930455	hsa-miR-152	CLIP-seq
MIRT1930456	hsa-miR-1913	CLIP-seq
MIRT780688	hsa-miR-197	CLIP-seq
MIRT1930457	hsa-miR-2277-3p	CLIP-seq
MIRT1930458	hsa-miR-3116	CLIP-seq
MIRT1930459	hsa-miR-3121-5p	CLIP-seq
MIRT1930460	hsa-miR-3136-3p	CLIP-seq
MIRT1930461	hsa-miR-3137	CLIP-seq
MIRT780697	hsa-miR-3155	CLIP-seq
MIRT780698	hsa-miR-3155b	CLIP-seq
MIRT780700	hsa-miR-3182	CLIP-seq
MIRT1930462	hsa-miR-3202	CLIP-seq
MIRT1930463	hsa-miR-324-3p	CLIP-seq
MIRT1930464	hsa-miR-3660	CLIP-seq
MIRT1930465	hsa-miR-3664-3p	CLIP-seq
MIRT1930466	hsa-miR-3936	CLIP-seq
MIRT780705	hsa-miR-3973	CLIP-seq
MIRT1930467	hsa-miR-4290	CLIP-seq
MIRT1930468	hsa-miR-4324	CLIP-seq
MIRT1930469	hsa-miR-4418	CLIP-seq
MIRT1930470	hsa-miR-4428	CLIP-seq
MIRT1930471	hsa-miR-4479	CLIP-seq
MIRT1930472	hsa-miR-4480	CLIP-seq
MIRT1930473	hsa-miR-4494	CLIP-seq
MIRT1930474	hsa-miR-4526	CLIP-seq
MIRT1930475	hsa-miR-4533	CLIP-seq
MIRT780713	hsa-miR-4652-3p	CLIP-seq
MIRT1930476	hsa-miR-4700-3p	CLIP-seq
MIRT1930477	hsa-miR-4733-3p	CLIP-seq
MIRT1930478	hsa-miR-4738-3p	CLIP-seq
MIRT780720	hsa-miR-4757-5p	CLIP-seq
MIRT1930479	hsa-miR-4776-3p	CLIP-seq
MIRT1930480	hsa-miR-483-3p	CLIP-seq
MIRT780723	hsa-miR-484	CLIP-seq
MIRT1930481	hsa-miR-499-3p	CLIP-seq
MIRT1930482	hsa-miR-499a-3p	CLIP-seq
MIRT1930483	hsa-miR-509-3-5p	CLIP-seq
MIRT1930484	hsa-miR-509-5p	CLIP-seq
MIRT780725	hsa-miR-5096	CLIP-seq
MIRT780726	hsa-miR-520g	CLIP-seq
MIRT780727	hsa-miR-520h	CLIP-seq
MIRT1930485	hsa-miR-548g	CLIP-seq
MIRT1930486	hsa-miR-663b	CLIP-seq
MIRT1930487	hsa-miR-668	CLIP-seq
MIRT1930488	hsa-miR-873	CLIP-seq
MIRT2171142	hsa-miR-1184	CLIP-seq
MIRT2171143	hsa-miR-1205	CLIP-seq
MIRT780674	hsa-miR-1224-3p	CLIP-seq
MIRT2171144	hsa-miR-1226	CLIP-seq
MIRT780676	hsa-miR-1237	CLIP-seq
MIRT780680	hsa-miR-1260	CLIP-seq
MIRT780681	hsa-miR-1260b	CLIP-seq
MIRT780683	hsa-miR-1280	CLIP-seq
MIRT2171145	hsa-miR-1292	CLIP-seq
MIRT2171146	hsa-miR-3140-5p	CLIP-seq
MIRT2171147	hsa-miR-3665	CLIP-seq
MIRT2171148	hsa-miR-3914	CLIP-seq
MIRT1930469	hsa-miR-4418	CLIP-seq
MIRT2171149	hsa-miR-4427	CLIP-seq
MIRT2171150	hsa-miR-4471	CLIP-seq
MIRT2171151	hsa-miR-4646-5p	CLIP-seq
MIRT780713	hsa-miR-4652-3p	CLIP-seq
MIRT2171152	hsa-miR-4695-5p	CLIP-seq
MIRT1930483	hsa-miR-509-3-5p	CLIP-seq
MIRT1930484	hsa-miR-509-5p	CLIP-seq
MIRT780728	hsa-miR-532-3p	CLIP-seq
MIRT2171153	hsa-miR-605	CLIP-seq
MIRT780731	hsa-miR-645	CLIP-seq
MIRT2171154	hsa-miR-764	CLIP-seq
MIRT2171155	hsa-miR-767-5p	CLIP-seq
MIRT1930488	hsa-miR-873	CLIP-seq
MIRT2435329	hsa-miR-4778-5p	CLIP-seq
MIRT2435329	hsa-miR-4778-5p	CLIP-seq
MIRT2443619	hsa-miR-103a	CLIP-seq
MIRT2443620	hsa-miR-107	CLIP-seq
MIRT2443621	hsa-miR-1301	CLIP-seq
MIRT780697	hsa-miR-3155	CLIP-seq
MIRT780698	hsa-miR-3155b	CLIP-seq
MIRT2443622	hsa-miR-4691-3p	CLIP-seq
MIRT1930477	hsa-miR-4733-3p	CLIP-seq
MIRT780723	hsa-miR-484	CLIP-seq
MIRT2443623	hsa-miR-5047	CLIP-seq
MIRT2443619	hsa-miR-103a	CLIP-seq
MIRT2443620	hsa-miR-107	CLIP-seq
MIRT2443621	hsa-miR-1301	CLIP-seq
MIRT780697	hsa-miR-3155	CLIP-seq
MIRT780698	hsa-miR-3155b	CLIP-seq
MIRT2443622	hsa-miR-4691-3p	CLIP-seq
MIRT1930477	hsa-miR-4733-3p	CLIP-seq
MIRT780723	hsa-miR-484	CLIP-seq
MIRT2443623	hsa-miR-5047	CLIP-seq

Show/Hide all(4)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005575	Component	Cellular_component	ND
GO:0006508	Process	Proteolysis	IEA
GO:0008237	Function	Metallopeptidase activity	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
615168	22231	ENSG00000174945

Protein

UniProt ID

Q400G9

Protein name

Archaemetzincin-1 (EC 3.4.-.-) (Archeobacterial metalloproteinase-like protein 1)

Protein function

Probable zinc metalloprotease.

Family and domains

Sequence

MLQCRPAQEFSFGPRALKDALVSTDAALQQLYVSAFSPAERLFLAEAYNPQRTLFCTLLI
RTGFDWLLSRPEAPEDFQTFHASLQHRKPRLARKHIYLQPIDLSEEPVGSSLLHQLCSCT
EAFFLGLRVKCLPSVAAASIRCSSRPSRDSDRLQLHTDGILSFLKNNKPGDALCVLGLTL
SDLYPHEAWSFTFSKFLPGHEVGVCSFARFSGEFPKSGPSAPDLALVEAAADGPEAPLQD
RGWALCFSALGMVQCCKVTCHELCHLLGLGNCRWLRCLMQGALSLDEALRRPLDLCPICL
RKLQHVLGFRLIERYQRLYTWTQAVVGTWPSQEAGEPSVWEDTPPASADSGMCCESDSEP
GTSVSEPLTPDAGSHTFASGPEEGLSYLAASEAPLPPGGPAEAIKEHERWLAMCIQALQR
EVAEEDLVQVDRAVDALDRWEMFTGQLPATRQDPPSSRDSVGLRKVLGDKFSSLRRKLSA
RKLARAESAPRPWDGEES

Sequence length

498

Interactions

View interactions

Associated diseases

Show/Hide Causal Diseases (2)

Causal
Disease name	Disease term	dbSNP ID	References
Chronic obstructive pulmonary disease	Chronic Obstructive Airway Disease	rs2227956, rs1008438, rs1043618, rs562047, rs1061581, rs2763979, rs6457452, rs13147758, rs1828591, rs13118928	30804561
Inflammatory bowel disease	Inflammatory Bowel Diseases	rs137853579, rs137853580, rs121909601, rs149491038, rs368287711, rs387907326, rs587777338, rs758439420, rs139868987, rs750447828, rs368138379, rs1329427406, rs1264862631, rs1192830343, rs1373354533, rs1419560997, rs1591263883, rs1989014468	28067908

Show/Hide Unknown Diseases (1)

Unknown
Disease name	Disease term	dbSNP ID	References
Ulcerative colitis	Ulcerative Colitis		23128233, 21297633, 28067908

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