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RASGEF1B (RasGEF domain family member 1B)
Gene
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
153020
Gene nameGene Name - the full gene name approved by the HGNC.
RasGEF domain family member 1B
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
RASGEF1B
SynonymsGene synonyms aliases
GPIG4
ChromosomeChromosome number
4
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4q21.21
miRNAmiRNA information provided by mirtarbase database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
miRTarBase ID miRNA Experiments Reference
MIRT437661 hsa-miR-195-5p Microarray, qRT-PCR 22815788
MIRT616347 hsa-miR-4668-5p HITS-CLIP 23824327
MIRT616348 hsa-miR-1287-3p HITS-CLIP 23824327
MIRT616349 hsa-miR-6868-3p HITS-CLIP 23824327
MIRT616350 hsa-miR-1248 HITS-CLIP 23824327
Transcription factors
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Transcription factor Regulation Reference
E2F1 Activation 18396012
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0005085 Function Guanyl-nucleotide exchange factor activity IDA 19645719
GO:0005769 Component Early endosome IEA
GO:0005770 Component Late endosome IEA
GO:0007264 Process Small GTPase mediated signal transduction IEA
GO:0030496 Component Midbody IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
UniProt ID Q0VAM2
Protein name Ras-GEF domain-containing family member 1B (GPI gamma-4)
Protein function Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00618 RasGEF_N
37 → 138
RasGEF N-terminal motif
 Domain
PF00617 RasGEF
208 → 403
RasGEF domain
 Family
Sequence
Sequence length 473
Interactions View interactions
Associated diseases
Gene miRNA Transcription factors Gene ontology Other IDs Protein Associated diseases
Causal
Disease name Disease term dbSNP ID References
Coronary artery disease Coronary Artery Disease rs137852988, rs121918313, rs-1, rs121918529, rs121918531, rs137852340, rs405509, rs1555800701, rs1215189537 29212778
Arthritis Juvenile arthritis rs1594890601, rs1594882933, rs184370809, rs776489319, rs1594883470 19565504
Unknown
Disease name Disease term dbSNP ID References
Juvenile arthritis Juvenile psoriatic arthritis 19565504
Seronegative polyarthritis Polyarthritis, Juvenile, Rheumatoid Factor Negative 19565504
Polyarthritis, rheumatoid factor positive Polyarthritis, Juvenile, Rheumatoid Factor Positive 19565504
Still disease Juvenile-Onset Still Disease 19565504

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