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MB21D2 (Mab-21 domain containing 2)

Gene

151963

Mab-21 domain containing 2

MB21D2

C3orf59, D2A, hMB21D2

3q29

Show/Hide all(167)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020219	hsa-miR-130b-3p	Sequencing	20371350
MIRT031178	hsa-miR-19b-3p	Sequencing	20371350
MIRT042369	hsa-miR-484	CLASH	23622248
MIRT566809	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT566808	hsa-miR-4517	PAR-CLIP	20371350
MIRT566807	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT566806	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT566805	hsa-miR-6847-5p	PAR-CLIP	20371350
MIRT566804	hsa-miR-4257	PAR-CLIP	20371350
MIRT566803	hsa-miR-1827	PAR-CLIP	20371350
MIRT400560	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT031178	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT020219	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT556229	hsa-miR-3666	PAR-CLIP	21572407
MIRT556228	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT556227	hsa-miR-4295	PAR-CLIP	21572407
MIRT556226	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT556225	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT556224	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT556223	hsa-miR-5692a	PAR-CLIP	21572407
MIRT556222	hsa-miR-5197-5p	PAR-CLIP	21572407
MIRT091421	hsa-miR-944	PAR-CLIP	21572407
MIRT556221	hsa-miR-302b-5p	PAR-CLIP	21572407
MIRT556220	hsa-miR-302d-5p	PAR-CLIP	21572407
MIRT556219	hsa-miR-4470	PAR-CLIP	21572407
MIRT556218	hsa-miR-567	PAR-CLIP	21572407
MIRT556217	hsa-miR-2116-5p	PAR-CLIP	21572407
MIRT556216	hsa-miR-22-5p	PAR-CLIP	21572407
MIRT556215	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT556214	hsa-miR-4473	PAR-CLIP	21572407
MIRT091416	hsa-miR-374a-5p	PAR-CLIP	21572407
MIRT091420	hsa-miR-374b-5p	PAR-CLIP	21572407
MIRT556213	hsa-miR-4677-5p	PAR-CLIP	21572407
MIRT440271	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440271	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT566809	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT566808	hsa-miR-4517	PAR-CLIP	20371350
MIRT566807	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT566806	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT566805	hsa-miR-6847-5p	PAR-CLIP	20371350
MIRT566804	hsa-miR-4257	PAR-CLIP	20371350
MIRT566803	hsa-miR-1827	PAR-CLIP	20371350
MIRT400560	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT031178	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT020219	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT556229	hsa-miR-3666	PAR-CLIP	21572407
MIRT556228	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT556227	hsa-miR-4295	PAR-CLIP	21572407
MIRT556226	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT556225	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT556224	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT556223	hsa-miR-5692a	PAR-CLIP	21572407
MIRT556222	hsa-miR-5197-5p	PAR-CLIP	21572407
MIRT091421	hsa-miR-944	PAR-CLIP	21572407
MIRT556221	hsa-miR-302b-5p	PAR-CLIP	21572407
MIRT556220	hsa-miR-302d-5p	PAR-CLIP	21572407
MIRT556219	hsa-miR-4470	PAR-CLIP	21572407
MIRT556218	hsa-miR-567	PAR-CLIP	21572407
MIRT556217	hsa-miR-2116-5p	PAR-CLIP	21572407
MIRT556216	hsa-miR-22-5p	PAR-CLIP	21572407
MIRT556215	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT556214	hsa-miR-4473	PAR-CLIP	21572407
MIRT091416	hsa-miR-374a-5p	PAR-CLIP	21572407
MIRT091420	hsa-miR-374b-5p	PAR-CLIP	21572407
MIRT556213	hsa-miR-4677-5p	PAR-CLIP	21572407
MIRT1134761	hsa-miR-2355-5p	CLIP-seq
MIRT1134762	hsa-miR-3143	CLIP-seq
MIRT1134763	hsa-miR-3146	CLIP-seq
MIRT1134764	hsa-miR-3679-3p	CLIP-seq
MIRT1134765	hsa-miR-3978	CLIP-seq
MIRT1134766	hsa-miR-4261	CLIP-seq
MIRT1134767	hsa-miR-4282	CLIP-seq
MIRT1134768	hsa-miR-4446-5p	CLIP-seq
MIRT1134769	hsa-miR-4662a-3p	CLIP-seq
MIRT1134770	hsa-miR-4719	CLIP-seq
MIRT1134771	hsa-miR-543	CLIP-seq
MIRT2038326	hsa-miR-34c-3p	CLIP-seq
MIRT2038327	hsa-miR-3908	CLIP-seq
MIRT2038328	hsa-miR-3922-5p	CLIP-seq
MIRT2038329	hsa-miR-3942-5p	CLIP-seq
MIRT2038330	hsa-miR-3973	CLIP-seq
MIRT2038331	hsa-miR-4307	CLIP-seq
MIRT2038332	hsa-miR-4668-3p	CLIP-seq
MIRT2038333	hsa-miR-4703-5p	CLIP-seq
MIRT2038334	hsa-miR-4753-5p	CLIP-seq
MIRT2038335	hsa-miR-4766-3p	CLIP-seq
MIRT2038336	hsa-miR-520g	CLIP-seq
MIRT2038337	hsa-miR-520h	CLIP-seq
MIRT2038338	hsa-miR-561	CLIP-seq
MIRT2038339	hsa-miR-607	CLIP-seq
MIRT2268162	hsa-miR-1284	CLIP-seq
MIRT2268163	hsa-miR-1287	CLIP-seq
MIRT2268164	hsa-miR-181a	CLIP-seq
MIRT2268165	hsa-miR-181b	CLIP-seq
MIRT2268166	hsa-miR-181c	CLIP-seq
MIRT2268167	hsa-miR-181d	CLIP-seq
MIRT2268168	hsa-miR-190	CLIP-seq
MIRT2268169	hsa-miR-190b	CLIP-seq
MIRT2268170	hsa-miR-3145-3p	CLIP-seq
MIRT2268171	hsa-miR-3148	CLIP-seq
MIRT2268172	hsa-miR-3201	CLIP-seq
MIRT2268173	hsa-miR-3652	CLIP-seq
MIRT2268174	hsa-miR-380	CLIP-seq
MIRT2268175	hsa-miR-3929	CLIP-seq
MIRT2268176	hsa-miR-4262	CLIP-seq
MIRT2268177	hsa-miR-4419b	CLIP-seq
MIRT2268178	hsa-miR-4430	CLIP-seq
MIRT2268179	hsa-miR-4478	CLIP-seq
MIRT2268180	hsa-miR-4495	CLIP-seq
MIRT2268181	hsa-miR-4520a-3p	CLIP-seq
MIRT2268182	hsa-miR-4520b-3p	CLIP-seq
MIRT2268183	hsa-miR-4529-3p	CLIP-seq
MIRT1134769	hsa-miR-4662a-3p	CLIP-seq
MIRT2268184	hsa-miR-4715-3p	CLIP-seq
MIRT1134770	hsa-miR-4719	CLIP-seq
MIRT2268185	hsa-miR-4775	CLIP-seq
MIRT2268186	hsa-miR-4780	CLIP-seq
MIRT2268187	hsa-miR-4791	CLIP-seq
MIRT2268188	hsa-miR-587	CLIP-seq
MIRT2268189	hsa-miR-645	CLIP-seq
MIRT2268190	hsa-miR-654-3p	CLIP-seq
MIRT2268191	hsa-miR-942	CLIP-seq
MIRT2390661	hsa-miR-3074-5p	CLIP-seq
MIRT2567863	hsa-miR-130a	CLIP-seq
MIRT2567864	hsa-miR-130b	CLIP-seq
MIRT2567865	hsa-miR-1343	CLIP-seq
MIRT2567866	hsa-miR-19a	CLIP-seq
MIRT2567867	hsa-miR-19b	CLIP-seq
MIRT2567868	hsa-miR-2110	CLIP-seq
MIRT2567869	hsa-miR-2116	CLIP-seq
MIRT2567870	hsa-miR-301a	CLIP-seq
MIRT2567871	hsa-miR-301b	CLIP-seq
MIRT2390661	hsa-miR-3074-5p	CLIP-seq
MIRT2567872	hsa-miR-3140-3p	CLIP-seq
MIRT2268170	hsa-miR-3145-3p	CLIP-seq
MIRT2567873	hsa-miR-3150a-3p	CLIP-seq
MIRT2567874	hsa-miR-3159	CLIP-seq
MIRT2567875	hsa-miR-3646	CLIP-seq
MIRT2567876	hsa-miR-3662	CLIP-seq
MIRT2567877	hsa-miR-374a	CLIP-seq
MIRT2567878	hsa-miR-374b	CLIP-seq
MIRT2038327	hsa-miR-3908	CLIP-seq
MIRT2038329	hsa-miR-3942-5p	CLIP-seq
MIRT2567879	hsa-miR-4260	CLIP-seq
MIRT2567880	hsa-miR-4450	CLIP-seq
MIRT2567881	hsa-miR-454	CLIP-seq
MIRT2567882	hsa-miR-4698	CLIP-seq
MIRT2038333	hsa-miR-4703-5p	CLIP-seq
MIRT2268184	hsa-miR-4715-3p	CLIP-seq
MIRT2038335	hsa-miR-4766-3p	CLIP-seq
MIRT2567883	hsa-miR-633	CLIP-seq
MIRT2567863	hsa-miR-130a	CLIP-seq
MIRT2567864	hsa-miR-130b	CLIP-seq
MIRT2567865	hsa-miR-1343	CLIP-seq
MIRT2567866	hsa-miR-19a	CLIP-seq
MIRT2567867	hsa-miR-19b	CLIP-seq
MIRT2567870	hsa-miR-301a	CLIP-seq
MIRT2567871	hsa-miR-301b	CLIP-seq
MIRT2390661	hsa-miR-3074-5p	CLIP-seq
MIRT2567872	hsa-miR-3140-3p	CLIP-seq
MIRT2268170	hsa-miR-3145-3p	CLIP-seq
MIRT2038327	hsa-miR-3908	CLIP-seq
MIRT2038329	hsa-miR-3942-5p	CLIP-seq
MIRT2567881	hsa-miR-454	CLIP-seq
MIRT2038333	hsa-miR-4703-5p	CLIP-seq
MIRT2268184	hsa-miR-4715-3p	CLIP-seq
MIRT2038335	hsa-miR-4766-3p	CLIP-seq

Show/Hide all(3)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0044877	Function	Protein-containing complex binding	IDA	23209302
GO:0045296	Function	Cadherin binding	HDA	25468996

MIM	HGNC	e!Ensembl
620914	30438	ENSG00000180611

Protein

UniProt ID

Q8IYB1

Protein name

Nucleotidyltransferase MB21D2 (EC 2.7.7.-) (Mab-21 domain-containing protein 2) (hMB21D2)

Protein function

Probable nucleotidyltransferase that catalyzes the formation of cyclic dinucleotide second messenger in response to some unknown stimulus.

PDB

7LT1

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03281	Mab-21	108 → 402	Mab-21 protein	Family

Sequence

MKMAAPTANKAASLGCNNKPAFPELDFRSGARVEELNKLIQEFTKHDQREYDDQRALEIH
TAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDLDLDELNVYARGTDYDMDFTL
LVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKDCCTIVDHINGATNYFFS
PTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVS
FKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKK
CISSSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPANYLAQEDYAAHFLLG
LIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKA
ANRLTLELQRRGSTTSIPSPQSDGGDPNQPDDRLAKKLQQLVTENPGKSISVFINPDDVT
RPHFRIDDKFF

Sequence length

491

Interactions

View interactions

Associated diseases

Show/Hide Causal Diseases (2)

Causal
Disease name	Disease term	dbSNP ID	References
Autoimmune diseases	Autoimmune Diseases, AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1, AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 2	rs41285370, rs869025224	30595370
Hypothyroidism	Hypothyroidism	rs869320723, rs121908862, rs121908863, rs121908865, rs121908866, rs121908867, rs121908870, rs121908871, rs121908872, rs2140110277, rs121908881, rs121908884, rs121908885, rs786205080, rs1586182912, rs121917847, rs104893655, rs104893657, rs104893658, rs104893659, rs104893660, rs104893656, rs121917719, rs786204790, rs189261858, rs879255608, rs868197660, rs879255609, rs1586744173, rs1586182837, rs771222349, rs1587618417, rs1601844140, rs760832986, rs780982673, rs1603336347, rs1691155605	30595370

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