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KLHL23 (kelch like family member 23)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
151230
Gene nameGene Name - the full gene name approved by the HGNC.
Kelch like family member 23
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
KLHL23
SynonymsGene synonyms aliases
DITHP
ChromosomeChromosome number
2
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2q31.1
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT021998 hsa-miR-128-3p Sequencing 20371350
MIRT024447 hsa-miR-215-5p Microarray 19074876
MIRT026423 hsa-miR-192-5p Microarray 19074876
MIRT027259 hsa-miR-101-3p Sequencing 20371350
MIRT030436 hsa-miR-24-3p Microarray 19748357
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25036637, 32814053
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q8NBE8
Protein name Kelch-like protein 23
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00651 BTB
26 134
BTB/POZ domain
Domain
PF07707 BACK
139 240
BTB And C-terminal Kelch
Domain
PF01344 Kelch_1
274 306
Kelch motif
Repeat
PF01344 Kelch_1
309 356
Kelch motif
Repeat
PF01344 Kelch_1
358 403
Kelch motif
Repeat
PF01344 Kelch_1
406 453
Kelch motif
Repeat
PF01344 Kelch_1
457 495
Kelch motif
Repeat
PF01344 Kelch_1
497 544
Kelch motif
Repeat
Sequence
Sequence length 558
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 31164008
Unknown
Disease name Disease term dbSNP ID References
Bipolar disorder Bipolar Disorder 31164008
Mental depression Major Depressive Disorder rs587778876, rs587778877 31164008

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