ZNF385B (zinc finger protein 385B)

Gene

• Entrez ID: 151126
• Gene name: Zinc finger protein 385B
• Gene symbol: ZNF385B
• Synonyms: ZNF533
• Chromosome: 2
• Chromosome location: 2q31.2-q31.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT024722	hsa-miR-215-5p	Microarray	19074876
MIRT026853	hsa-miR-192-5p	Microarray	19074876
MIRT1523592	hsa-miR-1278	CLIP-seq
MIRT1523593	hsa-miR-3120-3p	CLIP-seq
MIRT1523594	hsa-miR-325	CLIP-seq
MIRT1523595	hsa-miR-4672	CLIP-seq
MIRT1523596	hsa-miR-628-3p	CLIP-seq
MIRT1523597	hsa-miR-1283	CLIP-seq
MIRT1523598	hsa-miR-3678-3p	CLIP-seq
MIRT1523599	hsa-miR-3915	CLIP-seq
MIRT1523600	hsa-miR-3928	CLIP-seq
MIRT1523601	hsa-miR-5095	CLIP-seq
MIRT1523602	hsa-miR-552	CLIP-seq
MIRT2397532	hsa-miR-1275	CLIP-seq
MIRT2397533	hsa-miR-4525	CLIP-seq
MIRT2397534	hsa-miR-4665-5p	CLIP-seq
MIRT2397535	hsa-miR-4723-5p	CLIP-seq
MIRT2397536	hsa-miR-625	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002039	Function	P53 binding	IPI	22945289
GO:0003676	Function	Nucleic acid binding	IEA
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	IDA	22945289
GO:0008270	Function	Zinc ion binding	IEA
GO:0072332	Process	Intrinsic apoptotic signaling pathway by p53 class mediator	IDA	22945289

Other IDs

• MIM: 612344
• HGNC: 26332
• e!Ensembl: ENSG00000144331

Protein

• UniProt ID: Q569K4
• Protein name: Zinc finger protein 385B (Zinc finger protein 533)
• Protein function: May play a role in p53/TP53-mediated apoptosis.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12874	zf-met	34 → 58		Domain
  PF12874	zf-met	157 → 181		Domain
  PF12874	zf-met	285 → 309		Domain
  PF12874	zf-met	348 → 372		Domain

• Sequence:

  MNMANFLRGFEEKGIKNDRPEDQLSKEKKKILFSFCEVCNIQLNSAAQAQVHSNGKSHRK
  RVKQLSDGQPPPPAQASPSSNSSTGSTCHTTTLPALVRTPTLMMQPSLDIKPFMSFPVDS
  SSAVGLFPNFNTMDPVQKAVINHTFGVSIPPKKKQVISCNVCQLRFNSDSQAEAHYKGSK
  HAKKVKALDATKNKPKMVPSKDSAKANPSCSITPITGNNSDKSEDKGKLKASSSSQPSSS
  ESGSFLLKSGTTPLPPGAATSPSKSTNGAPGTVVESEEEKAKKLLYCSLCKVAVNSLSQL
  EAHNTGSKHKTMVEARNGAGPIKSYPRPGSRLKMQNGSKGSGLQNKTFHCEICDVHVNSE
  IQLKQHISSRRHKDRVAGKPLKPKYSPYNKLQRSPSILAAKLAFQKDMMKPLAPAFLSSP
  LAAAAAVSSALSLPPRPSASLFQAPAIPPALLRPGHGPIRATPASILFAPY

• Sequence length: 471

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Schizophrenia	Schizophrenia	rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313	26198764