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SLC9B1 (solute carrier family 9 member B1)
Gene
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
150159
Gene nameGene Name - the full gene name approved by the HGNC.
Solute carrier family 9 member B1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
SLC9B1
SynonymsGene synonyms aliases
NHA1, NHEDC1
ChromosomeChromosome number
4
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4q24
SummarySummary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is a sodium/hydrogen exchanger and transmembrane protein. Highly conserved orthologs of this gene have been found in other mammalian species. The expression of this gene may be limited to testis. Multiple transcript varian
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0005886 Component Plasma membrane TAS
GO:0006814 Process Sodium ion transport IEA
GO:0007338 Process Single fertilization IEA
GO:0015299 Function Solute:proton antiporter activity IEA
GO:0016021 Component Integral component of membrane IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q4ZJI4
Protein name Sodium/hydrogen exchanger 9B1 (Na(+)/H(+) exchanger-like domain-containing protein 1) (NHE domain-containing protein 1) (Sodium/hydrogen exchanger-like domain-containing protein 1) (Solute carrier family 9, subfamily B member 1)
Protein function Sperm-specific Na(+)/H(+) exchanger involved in intracellular pH regulation of spermatozoa. Involved in sperm motility and fertility.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00999 Na_H_Exchanger
96 → 491
Sodium/hydrogen exchanger family
 Family
Sequence
Sequence length 515
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
 
Reactome
    Stimuli-sensing channels
Associated diseases
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Causal
Disease name Disease term dbSNP ID References
Atrial fibrillation Atrial Fibrillation rs120074192, rs121908590, rs121908593, rs121434558, rs587776851, rs387906612, rs387906613, rs387906614, rs387906615, rs199472687, rs199472705, rs199473324, rs587777336, rs587777339, rs587777557, rs587777558, rs587777559, rs587777560, rs886037778, rs769405762, rs770372675 30061737, 29892015
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 30285260, 28991256
Wolfram syndrome WOLFRAM SYNDROME 2 rs63749888, rs28937891, rs104893879, rs28937892, rs1578609780, rs1191510461, rs104893880, rs104893881, rs1362648752, rs104893883, rs74315205, rs71524374, rs387906930, rs727503745, rs71530923, rs199946797, rs797045076, rs777580652, rs797046112, rs797046113, rs369107336, rs148953711, rs863224265, rs863224268, rs145639028, rs1064796781, rs1064794257, rs1064797306, rs774265764, rs760337383, rs760171298, rs372855769, rs1553879087, rs1553876668, rs1560422383, rs1560408865, rs1578307302, rs1443751733, rs1578612324, rs1730600472
Unknown
Disease name Disease term dbSNP ID References
Cardiovascular diseases Cardiovascular Diseases 30595370
Paroxysmal atrial fibrillation Paroxysmal atrial fibrillation rs199865688, rs397515994, rs757096307 29892015, 30061737

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