GediPNet logo

CSRP1 (cysteine and glycine rich protein 1)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
1465
Gene nameGene Name - the full gene name approved by the HGNC.
Cysteine and glycine rich protein 1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CSRP1
SynonymsGene synonyms aliases
CRP, CRP1, CSRP, CYRP, D1S181E, HEL-141, HEL-S-286
ChromosomeChromosome number
1
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q32.1
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the cysteine-rich protein (CSRP) family. This gene family includes a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-fing
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT001373 hsa-miR-1-3p pSILAC 18668040
MIRT022790 hsa-miR-124-3p Proteomics;Microarray 18668037
MIRT023316 hsa-miR-122-5p Microarray 17612493
MIRT001373 hsa-miR-1-3p Proteomics;Microarray 18668037
MIRT001373 hsa-miR-1-3p Proteomics 18668040
Transcription factors
Transcription factor Regulation Reference
CEBPB Activation 14522018
HNF1A Unknown 18292576
REL Activation 14522018
STAT3 Activation 8621622
STAT3 Unknown 18292576
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding HDA 22658674
GO:0005515 Function Protein binding IPI 32296183
GO:0005634 Component Nucleus IBA 21873635
GO:0005634 Component Nucleus IDA 26924529
GO:0005737 Component Cytoplasm IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P21291
Protein name Cysteine and glycine-rich protein 1 (Cysteine-rich protein 1) (CRP) (CRP1) (Epididymis luminal protein 141) (HEL-141)
Protein function Could play a role in neuronal development.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00412 LIM
10 66
LIM domain
Domain
PF00412 LIM
119 175
LIM domain
Domain
Sequence
MPNWGGGKKCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYCKS
CYGKKY
GPKGYGYGQGAGTLSTDKGESLGIKHEEAPGHRPTTNPNASKFAQKIGGSERCP
RCSQAVYAAEKVIGAGKSWHKACFRCAKCGKGLESTTLADKDGEIYCKGCYAKNF
GPKGF
GFGQGAGALVHSE
Sequence length 193
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
  Cytoskeleton in muscle cells  
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 17199135
Unknown
Disease name Disease term dbSNP ID References
Bipolar disorder Bipolar Disorder 23031404
Endometrial hyperplasia Endometrial Hyperplasia, Complex Endometrial Hyperplasia, Atypical Endometrial Hyperplasia, Simple Endometrial Hyperplasia 22248470
Prostatic neoplasms Prostatic Neoplasms 17199135

| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412