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MIPOL1 (mirror-image polydactyly 1)

Gene

145282

Mirror-image polydactyly 1

MIPOL1

CCDC193

14q13.3-q21.1

This gene encodes a coiled-coil domain-containing protein. The encoded protein may function as a tumor suppressor. A translocation that results in truncation of the protein encoded by this locus has been associated with mirror-image polydactyly, also know

Show/Hide all(212)

miRTarBase ID	miRNA	Experiments	Reference
MIRT024688	hsa-miR-215-5p	Microarray	19074876
MIRT026684	hsa-miR-192-5p	Microarray	19074876
MIRT039001	hsa-let-7a-3p	CLASH	23622248
MIRT723433	hsa-miR-5571-5p	HITS-CLIP	19536157
MIRT723432	hsa-miR-593-5p	HITS-CLIP	19536157
MIRT723431	hsa-miR-183-5p	HITS-CLIP	19536157
MIRT723430	hsa-miR-1271-5p	HITS-CLIP	19536157
MIRT723429	hsa-miR-96-5p	HITS-CLIP	19536157
MIRT504457	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT522482	hsa-miR-4495	HITS-CLIP	21572407
MIRT522481	hsa-miR-379-3p	HITS-CLIP	21572407
MIRT522480	hsa-miR-411-3p	HITS-CLIP	21572407
MIRT522479	hsa-miR-380-3p	HITS-CLIP	21572407
MIRT522478	hsa-miR-3650	HITS-CLIP	21572407
MIRT522477	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT504456	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT504455	hsa-miR-4666b	HITS-CLIP	21572407
MIRT504454	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT679285	hsa-miR-122-3p	HITS-CLIP	23824327
MIRT679284	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT679283	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT679282	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT679281	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT679280	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT679279	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679278	hsa-miR-1976	HITS-CLIP	23824327
MIRT679277	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679276	hsa-miR-4297	HITS-CLIP	23824327
MIRT679275	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT679274	hsa-miR-4497	HITS-CLIP	23824327
MIRT679273	hsa-miR-4279	HITS-CLIP	23824327
MIRT679272	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT522483	hsa-miR-4517	PAR-CLIP	21572407
MIRT504457	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT522482	hsa-miR-4495	PAR-CLIP	21572407
MIRT522481	hsa-miR-379-3p	PAR-CLIP	21572407
MIRT522480	hsa-miR-411-3p	PAR-CLIP	21572407
MIRT522479	hsa-miR-380-3p	PAR-CLIP	21572407
MIRT522478	hsa-miR-3650	PAR-CLIP	21572407
MIRT522477	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT504456	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT504455	hsa-miR-4666b	PAR-CLIP	21572407
MIRT504454	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT504457	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT504456	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT504455	hsa-miR-4666b	PAR-CLIP	21572407
MIRT504454	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT522483	hsa-miR-4517	PAR-CLIP	22012620
MIRT522482	hsa-miR-4495	PAR-CLIP	22012620
MIRT522481	hsa-miR-379-3p	PAR-CLIP	22012620
MIRT522480	hsa-miR-411-3p	PAR-CLIP	22012620
MIRT522479	hsa-miR-380-3p	PAR-CLIP	22012620
MIRT504456	hsa-miR-190a-3p	PAR-CLIP	22012620
MIRT504454	hsa-miR-1277-5p	PAR-CLIP	22012620
MIRT522483	hsa-miR-4517	PAR-CLIP	23446348
MIRT504457	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT522482	hsa-miR-4495	PAR-CLIP	23446348
MIRT522481	hsa-miR-379-3p	PAR-CLIP	23446348
MIRT522480	hsa-miR-411-3p	PAR-CLIP	23446348
MIRT522479	hsa-miR-380-3p	PAR-CLIP	23446348
MIRT522478	hsa-miR-3650	PAR-CLIP	23446348
MIRT522477	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT504456	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT504455	hsa-miR-4666b	PAR-CLIP	23446348
MIRT504454	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT504457	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT504456	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT504455	hsa-miR-4666b	PAR-CLIP	23446348
MIRT504454	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT723433	hsa-miR-5571-5p	HITS-CLIP	19536157
MIRT723432	hsa-miR-593-5p	HITS-CLIP	19536157
MIRT723431	hsa-miR-183-5p	HITS-CLIP	19536157
MIRT723430	hsa-miR-1271-5p	HITS-CLIP	19536157
MIRT723429	hsa-miR-96-5p	HITS-CLIP	19536157
MIRT504457	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT522482	hsa-miR-4495	HITS-CLIP	21572407
MIRT522481	hsa-miR-379-3p	HITS-CLIP	21572407
MIRT522480	hsa-miR-411-3p	HITS-CLIP	21572407
MIRT522479	hsa-miR-380-3p	HITS-CLIP	21572407
MIRT522478	hsa-miR-3650	HITS-CLIP	21572407
MIRT522477	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT504456	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT504455	hsa-miR-4666b	HITS-CLIP	21572407
MIRT504454	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT679285	hsa-miR-122-3p	HITS-CLIP	23824327
MIRT679284	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT679283	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT679282	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT679281	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT679280	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT679279	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT679278	hsa-miR-1976	HITS-CLIP	23824327
MIRT679277	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679276	hsa-miR-4297	HITS-CLIP	23824327
MIRT679275	hsa-miR-5581-5p	HITS-CLIP	23824327
MIRT679274	hsa-miR-4497	HITS-CLIP	23824327
MIRT679273	hsa-miR-4279	HITS-CLIP	23824327
MIRT679272	hsa-miR-5001-3p	HITS-CLIP	23824327
MIRT522483	hsa-miR-4517	PAR-CLIP	21572407
MIRT504457	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT522482	hsa-miR-4495	PAR-CLIP	21572407
MIRT522481	hsa-miR-379-3p	PAR-CLIP	21572407
MIRT522480	hsa-miR-411-3p	PAR-CLIP	21572407
MIRT522479	hsa-miR-380-3p	PAR-CLIP	21572407
MIRT522478	hsa-miR-3650	PAR-CLIP	21572407
MIRT522477	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT504456	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT504455	hsa-miR-4666b	PAR-CLIP	21572407
MIRT504454	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT504457	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT504456	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT504455	hsa-miR-4666b	PAR-CLIP	21572407
MIRT504454	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT522483	hsa-miR-4517	PAR-CLIP	22012620
MIRT522482	hsa-miR-4495	PAR-CLIP	22012620
MIRT522481	hsa-miR-379-3p	PAR-CLIP	22012620
MIRT522480	hsa-miR-411-3p	PAR-CLIP	22012620
MIRT522479	hsa-miR-380-3p	PAR-CLIP	22012620
MIRT504456	hsa-miR-190a-3p	PAR-CLIP	22012620
MIRT504454	hsa-miR-1277-5p	PAR-CLIP	22012620
MIRT522483	hsa-miR-4517	PAR-CLIP	23446348
MIRT504457	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT522482	hsa-miR-4495	PAR-CLIP	23446348
MIRT522481	hsa-miR-379-3p	PAR-CLIP	23446348
MIRT522480	hsa-miR-411-3p	PAR-CLIP	23446348
MIRT522479	hsa-miR-380-3p	PAR-CLIP	23446348
MIRT522478	hsa-miR-3650	PAR-CLIP	23446348
MIRT522477	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT504456	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT504455	hsa-miR-4666b	PAR-CLIP	23446348
MIRT504454	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT504457	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT504456	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT504455	hsa-miR-4666b	PAR-CLIP	23446348
MIRT504454	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT1149396	hsa-miR-23a	CLIP-seq
MIRT1149397	hsa-miR-23b	CLIP-seq
MIRT1149398	hsa-miR-23c	CLIP-seq
MIRT1149399	hsa-miR-4643	CLIP-seq
MIRT1149400	hsa-miR-1323	CLIP-seq
MIRT1149401	hsa-miR-203	CLIP-seq
MIRT1149402	hsa-miR-2053	CLIP-seq
MIRT1149403	hsa-miR-2113	CLIP-seq
MIRT1149404	hsa-miR-302f	CLIP-seq
MIRT1149405	hsa-miR-3144-3p	CLIP-seq
MIRT1149406	hsa-miR-3163	CLIP-seq
MIRT1149407	hsa-miR-340	CLIP-seq
MIRT1149408	hsa-miR-4282	CLIP-seq
MIRT1149409	hsa-miR-4464	CLIP-seq
MIRT1149410	hsa-miR-4668-3p	CLIP-seq
MIRT1149411	hsa-miR-4748	CLIP-seq
MIRT1149412	hsa-miR-4753-3p	CLIP-seq
MIRT1149413	hsa-miR-4797-5p	CLIP-seq
MIRT1149414	hsa-miR-4799-5p	CLIP-seq
MIRT1149415	hsa-miR-548o	CLIP-seq
MIRT1149416	hsa-miR-569	CLIP-seq
MIRT1149417	hsa-miR-590-3p	CLIP-seq
MIRT1149418	hsa-miR-600	CLIP-seq
MIRT1149419	hsa-miR-633	CLIP-seq
MIRT1149420	hsa-miR-875-5p	CLIP-seq
MIRT2042502	hsa-miR-338-5p	CLIP-seq
MIRT2042503	hsa-miR-3611	CLIP-seq
MIRT2042504	hsa-miR-141	CLIP-seq
MIRT2042505	hsa-miR-200a	CLIP-seq
MIRT2272129	hsa-miR-140-5p	CLIP-seq
MIRT2272130	hsa-miR-15a	CLIP-seq
MIRT2272131	hsa-miR-15b	CLIP-seq
MIRT2272132	hsa-miR-16	CLIP-seq
MIRT2272133	hsa-miR-182	CLIP-seq
MIRT2272134	hsa-miR-1910	CLIP-seq
MIRT2272135	hsa-miR-195	CLIP-seq
MIRT2272136	hsa-miR-214	CLIP-seq
MIRT2272137	hsa-miR-3189-3p	CLIP-seq
MIRT2272138	hsa-miR-323b-3p	CLIP-seq
MIRT2272139	hsa-miR-3619-5p	CLIP-seq
MIRT2272140	hsa-miR-3658	CLIP-seq
MIRT2272141	hsa-miR-374a	CLIP-seq
MIRT2272142	hsa-miR-374b	CLIP-seq
MIRT2272143	hsa-miR-3940-5p	CLIP-seq
MIRT2272144	hsa-miR-424	CLIP-seq
MIRT1149408	hsa-miR-4282	CLIP-seq
MIRT2272145	hsa-miR-4291	CLIP-seq
MIRT2272146	hsa-miR-4470	CLIP-seq
MIRT2272147	hsa-miR-4507	CLIP-seq
MIRT2272148	hsa-miR-4796-3p	CLIP-seq
MIRT1149414	hsa-miR-4799-5p	CLIP-seq
MIRT2272149	hsa-miR-497	CLIP-seq
MIRT2272150	hsa-miR-517b	CLIP-seq
MIRT2272151	hsa-miR-520g	CLIP-seq
MIRT2272152	hsa-miR-520h	CLIP-seq
MIRT2272153	hsa-miR-545	CLIP-seq
MIRT2272154	hsa-miR-761	CLIP-seq
MIRT2272155	hsa-miR-922	CLIP-seq
MIRT2272156	hsa-miR-944	CLIP-seq
MIRT2042504	hsa-miR-141	CLIP-seq
MIRT2042505	hsa-miR-200a	CLIP-seq
MIRT2454144	hsa-miR-1185	CLIP-seq
MIRT2454145	hsa-miR-3679-5p	CLIP-seq
MIRT2454146	hsa-miR-4712-3p	CLIP-seq
MIRT2454147	hsa-miR-601	CLIP-seq
MIRT2454148	hsa-miR-616	CLIP-seq
MIRT2571158	hsa-miR-128	CLIP-seq
MIRT2571159	hsa-miR-320a	CLIP-seq
MIRT2571160	hsa-miR-320b	CLIP-seq
MIRT2571161	hsa-miR-320c	CLIP-seq
MIRT2571162	hsa-miR-320d	CLIP-seq
MIRT2042502	hsa-miR-338-5p	CLIP-seq
MIRT2571163	hsa-miR-3681	CLIP-seq
MIRT2571164	hsa-miR-4429	CLIP-seq
MIRT2571165	hsa-miR-4691-5p	CLIP-seq
MIRT2571166	hsa-miR-4699-3p	CLIP-seq
MIRT2571167	hsa-miR-548c-3p	CLIP-seq

Show/Hide all(3)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 25910212, 26871637, 29892012, 31515488, 32296183
GO:0005634	Component	Nucleus	IDA	19667180
GO:0042802	Function	Identical protein binding	IPI	25416956, 32296183

MIM	HGNC	e!Ensembl
606850	21460	ENSG00000151338

Protein

UniProt ID

Q8TD10

Protein name

Mirror-image polydactyly gene 1 protein

Family and domains

Sequence

MENWSKDITHSYLEQETTGINKSTQPDEQLTMNSEKSMHRKSTELVNEITCENTEWPGQR
STNFQIISSYPDDESVYCTTEKYNVMEHRHNDMHYECMTPCQVTSDSDKEKTIAFLLKEL
DILRTSNKKLQQKLAKEDKEQRKLKFKLELQEKETEAKIAEKTAALVEEVYFAQKERDEA
VMSRLQLAIEERDEAIARAKHMEMSLKVLENINPEENDMTLQELLNRINNADTGIAIQKN
GAIIVDRIYKTKECKMRITAEEMSALIEERDAALSKCKRLEQELHHVKEQNQTSANNMRH
LTAENNQERALKAKLLSMQQARETAVQQYKKLEEEIQTLRVYYSLHKSLSQEENLKDQFN
YTLSTYEEALKNRENIVSITQQQNEELATQLQQALTERANMELQLQHAREASQVANEKVQ
KLERLVDVLRKKVGTGTMRTVI

Sequence length

442

Interactions

View interactions

Associated diseases

Show/Hide Causal Diseases (1)

Causal
Disease name	Disease term	dbSNP ID	References
Polydactyly	Polydactyly	rs1583729398, rs121917709, rs1583734240, rs121917714, rs397507422, rs398122899, rs587776959, rs386833752, rs1057518698, rs1060499558, rs755938967, rs1375768446, rs1309855392, rs1565601979, rs748321474, rs368652620, rs1562587032, rs760694987	11954550

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