MPP7 (MAGUK p55 scaffold protein 7)

Gene

• Entrez ID: 143098
• Gene name: MAGUK p55 scaffold protein 7
• Gene symbol: MPP7
• Synonyms: -
• Chromosome: 10
• Chromosome location: 10p12.1
• Summary: The protein encoded by this gene is a member of the p55 Stardust family of membrane-associated guanylate kinase (MAGUK) proteins, which function in the establishment of epithelial cell polarity. This family member forms a complex with the polarity protein

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT028259	hsa-miR-32-5p	Sequencing	20371350
MIRT1156495	hsa-miR-10a	CLIP-seq
MIRT1156496	hsa-miR-10b	CLIP-seq
MIRT1156497	hsa-miR-1179	CLIP-seq
MIRT1156498	hsa-miR-122	CLIP-seq
MIRT1156499	hsa-miR-1253	CLIP-seq
MIRT1156500	hsa-miR-1264	CLIP-seq
MIRT1156501	hsa-miR-1273e	CLIP-seq
MIRT1156502	hsa-miR-1285	CLIP-seq
MIRT1156503	hsa-miR-1287	CLIP-seq
MIRT1156504	hsa-miR-134	CLIP-seq
MIRT1156505	hsa-miR-140-5p	CLIP-seq
MIRT1156506	hsa-miR-154	CLIP-seq
MIRT1156507	hsa-miR-23a	CLIP-seq
MIRT1156508	hsa-miR-23b	CLIP-seq
MIRT1156509	hsa-miR-23c	CLIP-seq
MIRT1156510	hsa-miR-31	CLIP-seq
MIRT1156511	hsa-miR-3118	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT1156513	hsa-miR-3135b	CLIP-seq
MIRT1156514	hsa-miR-3164	CLIP-seq
MIRT1156515	hsa-miR-3165	CLIP-seq
MIRT1156516	hsa-miR-3173-3p	CLIP-seq
MIRT1156517	hsa-miR-3187-5p	CLIP-seq
MIRT1156518	hsa-miR-3198	CLIP-seq
MIRT1156519	hsa-miR-339-5p	CLIP-seq
MIRT1156520	hsa-miR-3613-3p	CLIP-seq
MIRT1156521	hsa-miR-3650	CLIP-seq
MIRT1156522	hsa-miR-3653	CLIP-seq
MIRT1156523	hsa-miR-3658	CLIP-seq
MIRT1156524	hsa-miR-3662	CLIP-seq
MIRT1156525	hsa-miR-3667-5p	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156529	hsa-miR-371-5p	CLIP-seq
MIRT1156530	hsa-miR-371b-5p	CLIP-seq
MIRT1156531	hsa-miR-380	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT1156533	hsa-miR-3922-5p	CLIP-seq
MIRT1156534	hsa-miR-4251	CLIP-seq
MIRT1156535	hsa-miR-4279	CLIP-seq
MIRT1156536	hsa-miR-4293	CLIP-seq
MIRT1156537	hsa-miR-4307	CLIP-seq
MIRT1156538	hsa-miR-4309	CLIP-seq
MIRT1156539	hsa-miR-4329	CLIP-seq
MIRT1156540	hsa-miR-4421	CLIP-seq
MIRT1156541	hsa-miR-4433	CLIP-seq
MIRT1156542	hsa-miR-4434	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT1156544	hsa-miR-4495	CLIP-seq
MIRT1156545	hsa-miR-4505	CLIP-seq
MIRT1156546	hsa-miR-4516	CLIP-seq
MIRT1156547	hsa-miR-4517	CLIP-seq
MIRT1156548	hsa-miR-4531	CLIP-seq
MIRT1156549	hsa-miR-4695-5p	CLIP-seq
MIRT1156550	hsa-miR-4696	CLIP-seq
MIRT1156551	hsa-miR-4717-3p	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156553	hsa-miR-4725-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT1156555	hsa-miR-4753-5p	CLIP-seq
MIRT1156556	hsa-miR-502-5p	CLIP-seq
MIRT1156557	hsa-miR-504	CLIP-seq
MIRT1156558	hsa-miR-5096	CLIP-seq
MIRT1156559	hsa-miR-564	CLIP-seq
MIRT1156560	hsa-miR-576-5p	CLIP-seq
MIRT1156561	hsa-miR-592	CLIP-seq
MIRT1156562	hsa-miR-593	CLIP-seq
MIRT1156563	hsa-miR-597	CLIP-seq
MIRT1156564	hsa-miR-603	CLIP-seq
MIRT1156565	hsa-miR-612	CLIP-seq
MIRT1156566	hsa-miR-665	CLIP-seq
MIRT1156567	hsa-miR-935	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq
MIRT1156569	hsa-miR-944	CLIP-seq
MIRT1156497	hsa-miR-1179	CLIP-seq
MIRT2044797	hsa-miR-1225-3p	CLIP-seq
MIRT2044798	hsa-miR-1233	CLIP-seq
MIRT1156499	hsa-miR-1253	CLIP-seq
MIRT1156500	hsa-miR-1264	CLIP-seq
MIRT1156501	hsa-miR-1273e	CLIP-seq
MIRT2044799	hsa-miR-139-5p	CLIP-seq
MIRT1156506	hsa-miR-154	CLIP-seq
MIRT2044800	hsa-miR-181a	CLIP-seq
MIRT2044801	hsa-miR-181b	CLIP-seq
MIRT2044802	hsa-miR-181c	CLIP-seq
MIRT2044803	hsa-miR-181d	CLIP-seq
MIRT2044804	hsa-miR-217	CLIP-seq
MIRT2044805	hsa-miR-223	CLIP-seq
MIRT2044806	hsa-miR-298	CLIP-seq
MIRT1156510	hsa-miR-31	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT2044807	hsa-miR-3127-5p	CLIP-seq
MIRT2044808	hsa-miR-3201	CLIP-seq
MIRT2044809	hsa-miR-340	CLIP-seq
MIRT2044810	hsa-miR-3671	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156530	hsa-miR-371b-5p	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT2044811	hsa-miR-3941	CLIP-seq
MIRT2044812	hsa-miR-3974	CLIP-seq
MIRT1156534	hsa-miR-4251	CLIP-seq
MIRT2044813	hsa-miR-4262	CLIP-seq
MIRT1156536	hsa-miR-4293	CLIP-seq
MIRT1156537	hsa-miR-4307	CLIP-seq
MIRT2044814	hsa-miR-4328	CLIP-seq
MIRT1156539	hsa-miR-4329	CLIP-seq
MIRT1156541	hsa-miR-4433	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT2044815	hsa-miR-4476	CLIP-seq
MIRT1156547	hsa-miR-4517	CLIP-seq
MIRT2044816	hsa-miR-4530	CLIP-seq
MIRT2044817	hsa-miR-4539	CLIP-seq
MIRT2044818	hsa-miR-466	CLIP-seq
MIRT2044819	hsa-miR-4666-5p	CLIP-seq
MIRT2044820	hsa-miR-4668-3p	CLIP-seq
MIRT2044821	hsa-miR-4672	CLIP-seq
MIRT2044822	hsa-miR-4680-5p	CLIP-seq
MIRT1156550	hsa-miR-4696	CLIP-seq
MIRT2044823	hsa-miR-4697-3p	CLIP-seq
MIRT2044824	hsa-miR-4699-3p	CLIP-seq
MIRT2044825	hsa-miR-4705	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT2044826	hsa-miR-4731-3p	CLIP-seq
MIRT2044827	hsa-miR-4786-5p	CLIP-seq
MIRT2044828	hsa-miR-4791	CLIP-seq
MIRT2044829	hsa-miR-4801	CLIP-seq
MIRT2044830	hsa-miR-493	CLIP-seq
MIRT2044831	hsa-miR-513c	CLIP-seq
MIRT2044832	hsa-miR-514b-5p	CLIP-seq
MIRT2044833	hsa-miR-518e	CLIP-seq
MIRT2044834	hsa-miR-548c-3p	CLIP-seq
MIRT2044835	hsa-miR-590-3p	CLIP-seq
MIRT2044836	hsa-miR-607	CLIP-seq
MIRT2044837	hsa-miR-634	CLIP-seq
MIRT2044838	hsa-miR-656	CLIP-seq
MIRT1156566	hsa-miR-665	CLIP-seq
MIRT2044839	hsa-miR-769-5p	CLIP-seq
MIRT2044840	hsa-miR-888	CLIP-seq
MIRT2044841	hsa-miR-922	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq
MIRT1156569	hsa-miR-944	CLIP-seq
MIRT1156497	hsa-miR-1179	CLIP-seq
MIRT2274014	hsa-miR-1207-5p	CLIP-seq
MIRT2044797	hsa-miR-1225-3p	CLIP-seq
MIRT2044798	hsa-miR-1233	CLIP-seq
MIRT1156501	hsa-miR-1273e	CLIP-seq
MIRT2274015	hsa-miR-1297	CLIP-seq
MIRT2274016	hsa-miR-1305	CLIP-seq
MIRT2044799	hsa-miR-139-5p	CLIP-seq
MIRT2044800	hsa-miR-181a	CLIP-seq
MIRT2044801	hsa-miR-181b	CLIP-seq
MIRT2044802	hsa-miR-181c	CLIP-seq
MIRT2044803	hsa-miR-181d	CLIP-seq
MIRT2274017	hsa-miR-199a-3p	CLIP-seq
MIRT2274018	hsa-miR-199b-3p	CLIP-seq
MIRT2044804	hsa-miR-217	CLIP-seq
MIRT2044805	hsa-miR-223	CLIP-seq
MIRT2274019	hsa-miR-26a	CLIP-seq
MIRT2274020	hsa-miR-26b	CLIP-seq
MIRT2274021	hsa-miR-3064-3p	CLIP-seq
MIRT1156510	hsa-miR-31	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT2274022	hsa-miR-3129-5p	CLIP-seq
MIRT2274023	hsa-miR-3158-3p	CLIP-seq
MIRT1156514	hsa-miR-3164	CLIP-seq
MIRT1156515	hsa-miR-3165	CLIP-seq
MIRT2044808	hsa-miR-3201	CLIP-seq
MIRT2274024	hsa-miR-3614-5p	CLIP-seq
MIRT2274025	hsa-miR-3647-3p	CLIP-seq
MIRT2274026	hsa-miR-3660	CLIP-seq
MIRT1156525	hsa-miR-3667-5p	CLIP-seq
MIRT2044810	hsa-miR-3671	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156530	hsa-miR-371b-5p	CLIP-seq
MIRT2274027	hsa-miR-378	CLIP-seq
MIRT2274028	hsa-miR-378b	CLIP-seq
MIRT2274029	hsa-miR-378c	CLIP-seq
MIRT2274030	hsa-miR-378d	CLIP-seq
MIRT2274031	hsa-miR-378e	CLIP-seq
MIRT2274032	hsa-miR-378f	CLIP-seq
MIRT2274033	hsa-miR-378h	CLIP-seq
MIRT2274034	hsa-miR-378i	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT2044811	hsa-miR-3941	CLIP-seq
MIRT2274035	hsa-miR-409-3p	CLIP-seq
MIRT2274036	hsa-miR-422a	CLIP-seq
MIRT2044813	hsa-miR-4262	CLIP-seq
MIRT1156536	hsa-miR-4293	CLIP-seq
MIRT1156537	hsa-miR-4307	CLIP-seq
MIRT2044814	hsa-miR-4328	CLIP-seq
MIRT2274037	hsa-miR-4420	CLIP-seq
MIRT1156541	hsa-miR-4433	CLIP-seq
MIRT2274038	hsa-miR-4457	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT2274039	hsa-miR-4465	CLIP-seq
MIRT2274040	hsa-miR-4520a-3p	CLIP-seq
MIRT2274041	hsa-miR-4526	CLIP-seq
MIRT2274042	hsa-miR-4638-3p	CLIP-seq
MIRT2044818	hsa-miR-466	CLIP-seq
MIRT2044819	hsa-miR-4666-5p	CLIP-seq
MIRT2044821	hsa-miR-4672	CLIP-seq
MIRT1156550	hsa-miR-4696	CLIP-seq
MIRT2044824	hsa-miR-4699-3p	CLIP-seq
MIRT2044825	hsa-miR-4705	CLIP-seq
MIRT2274043	hsa-miR-4715-3p	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT2044826	hsa-miR-4731-3p	CLIP-seq
MIRT1156555	hsa-miR-4753-5p	CLIP-seq
MIRT2274044	hsa-miR-4760-5p	CLIP-seq
MIRT2274045	hsa-miR-4763-3p	CLIP-seq
MIRT2044828	hsa-miR-4791	CLIP-seq
MIRT2044829	hsa-miR-4801	CLIP-seq
MIRT2274046	hsa-miR-498	CLIP-seq
MIRT1156558	hsa-miR-5096	CLIP-seq
MIRT2274047	hsa-miR-513a-3p	CLIP-seq
MIRT2044831	hsa-miR-513c	CLIP-seq
MIRT2044832	hsa-miR-514b-5p	CLIP-seq
MIRT2274048	hsa-miR-550b	CLIP-seq
MIRT2274049	hsa-miR-556-3p	CLIP-seq
MIRT1156559	hsa-miR-564	CLIP-seq
MIRT2274050	hsa-miR-578	CLIP-seq
MIRT2274051	hsa-miR-582-5p	CLIP-seq
MIRT2044835	hsa-miR-590-3p	CLIP-seq
MIRT2044836	hsa-miR-607	CLIP-seq
MIRT2274052	hsa-miR-628-5p	CLIP-seq
MIRT2044838	hsa-miR-656	CLIP-seq
MIRT1156566	hsa-miR-665	CLIP-seq
MIRT2044840	hsa-miR-888	CLIP-seq
MIRT2274053	hsa-miR-936	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq
MIRT1156569	hsa-miR-944	CLIP-seq
MIRT2044797	hsa-miR-1225-3p	CLIP-seq
MIRT2044798	hsa-miR-1233	CLIP-seq
MIRT1156501	hsa-miR-1273e	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq
MIRT2431261	hsa-miR-3618	CLIP-seq
MIRT1156531	hsa-miR-380	CLIP-seq
MIRT1156544	hsa-miR-4495	CLIP-seq
MIRT2431261	hsa-miR-3618	CLIP-seq
MIRT1156531	hsa-miR-380	CLIP-seq
MIRT1156544	hsa-miR-4495	CLIP-seq
MIRT2442387	hsa-miR-1251	CLIP-seq
MIRT2044797	hsa-miR-1225-3p	CLIP-seq
MIRT2044798	hsa-miR-1233	CLIP-seq
MIRT1156501	hsa-miR-1273e	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq
MIRT1156495	hsa-miR-10a	CLIP-seq
MIRT1156496	hsa-miR-10b	CLIP-seq
MIRT2044797	hsa-miR-1225-3p	CLIP-seq
MIRT2044798	hsa-miR-1233	CLIP-seq
MIRT1156501	hsa-miR-1273e	CLIP-seq
MIRT1156510	hsa-miR-31	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT1156519	hsa-miR-339-5p	CLIP-seq
MIRT1156520	hsa-miR-3613-3p	CLIP-seq
MIRT2431261	hsa-miR-3618	CLIP-seq
MIRT1156525	hsa-miR-3667-5p	CLIP-seq
MIRT2572867	hsa-miR-3679-3p	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156529	hsa-miR-371-5p	CLIP-seq
MIRT1156530	hsa-miR-371b-5p	CLIP-seq
MIRT1156531	hsa-miR-380	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT1156536	hsa-miR-4293	CLIP-seq
MIRT1156540	hsa-miR-4421	CLIP-seq
MIRT1156541	hsa-miR-4433	CLIP-seq
MIRT2572868	hsa-miR-4446-5p	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT1156544	hsa-miR-4495	CLIP-seq
MIRT1156550	hsa-miR-4696	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156553	hsa-miR-4725-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT1156557	hsa-miR-504	CLIP-seq
MIRT2572869	hsa-miR-548l	CLIP-seq
MIRT2572870	hsa-miR-548n	CLIP-seq
MIRT1156566	hsa-miR-665	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq
MIRT1156495	hsa-miR-10a	CLIP-seq
MIRT1156496	hsa-miR-10b	CLIP-seq
MIRT2044797	hsa-miR-1225-3p	CLIP-seq
MIRT2044798	hsa-miR-1233	CLIP-seq
MIRT1156501	hsa-miR-1273e	CLIP-seq
MIRT1156510	hsa-miR-31	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT1156519	hsa-miR-339-5p	CLIP-seq
MIRT1156520	hsa-miR-3613-3p	CLIP-seq
MIRT1156525	hsa-miR-3667-5p	CLIP-seq
MIRT2572867	hsa-miR-3679-3p	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156529	hsa-miR-371-5p	CLIP-seq
MIRT1156530	hsa-miR-371b-5p	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT1156540	hsa-miR-4421	CLIP-seq
MIRT1156541	hsa-miR-4433	CLIP-seq
MIRT2572868	hsa-miR-4446-5p	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT1156550	hsa-miR-4696	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156553	hsa-miR-4725-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT1156557	hsa-miR-504	CLIP-seq
MIRT1156566	hsa-miR-665	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	17237226, 24366813, 28514442, 32296183
GO:0005654	Component	Nucleoplasm	IDA
GO:0005912	Component	Adherens junction	IDA	17237226
GO:0005923	Component	Bicellular tight junction	IDA	17332497
GO:0005938	Component	Cell cortex	IEA
GO:0016328	Component	Lateral plasma membrane	IEA
GO:0019904	Function	Protein domain specific binding	IPI	17332497
GO:0030010	Process	Establishment of cell polarity	TAS	17332497
GO:0030054	Component	Cell junction	IDA
GO:0031334	Process	Positive regulation of protein-containing complex assembly	IDA	17237226
GO:0031334	Process	Positive regulation of protein-containing complex assembly	TAS	14719143
GO:0035591	Function	Signaling adaptor activity	NAS	14719143
GO:0035591	Function	Signaling adaptor activity	TAS	20702775
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0060090	Function	Molecular adaptor activity	IDA	17237226, 20702775
GO:0070830	Process	Bicellular tight junction assembly	IDA	17332497
GO:0071896	Process	Protein localization to adherens junction	IMP	17237226
GO:0097025	Component	MPP7-DLG1-LIN7 complex	IDA	17237226, 20702775

Other IDs

• MIM: 610973
• HGNC: 26542
• e!Ensembl: ENSG00000150054

Protein

• UniProt ID: Q5T2T1
• Protein name: MAGUK p55 subfamily member 7
• Protein function: Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.
• PDB: 3LRA, 3O46
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02828	L27	15 → 67	L27 domain	Domain
  PF02828	L27	73 → 124	L27 domain	Domain
  PF00595	PDZ	139 → 217	PDZ domain	Domain
  PF00018	SH3_1	234 → 290	SH3 domain	Domain
  PF00625	Guanylate_kin	367 → 562	Guanylate kinase	Domain

• Sequence:

  MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYY
  EKQSPVPILHGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYD
  PVLPPMPEDIDDEEDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIH
  VGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYN
  PNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLAL
  RRPEILVQPLKVSNRKSSGFRKSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPY
  RRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIFI
  SKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFK
  PYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFD
  KIIINDDLTVAFNELKTTFDKLETETHWVPVSWLHS

• Sequence length: 576

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Asthma	Asthma	rs324981, rs121912630, rs150116809, rs4950928, rs708494, rs1581842283	25918132
Glaucoma	Glaucoma, Open-Angle	rs121918355, rs1566660365, rs1566635134, rs121918356, rs1566634475, rs28936700, rs55771538, rs28936701, rs104893622, rs55989760, rs72549387, rs104893628, rs2125316417, rs104893629, rs74315328, rs121909193, rs74315330, rs74315329, rs74315332, rs74315334, rs74315336, rs74315338, rs74315341, rs121909194, rs74315331, rs1558603396, rs387907175, rs587778873, rs587778875, rs104894979, rs137854895, rs766425037, rs72549380, rs148542782, rs541217363, rs753021890, rs771076928, rs56010818, rs777678299, rs1446110883, rs1573274915, rs1587545234, rs751768343, rs944452644	27001270