Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
140685 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
Zinc finger and BTB domain containing 46 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
ZBTB46 |
SynonymsGene synonyms aliases
|
BTBD4, BZEL, RINZF, ZNF340, dJ583P15.7, dJ583P15.8 |
ChromosomeChromosome number
|
20 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
20q13.33 |
miRNAmiRNA information provided by mirtarbase database.
|
|
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
GO ID |
Ontology |
Definition |
Evidence |
Reference |
GO:0000785 |
Component |
Chromatin |
ISA |
|
GO:0000977 |
Function |
RNA polymerase II transcription regulatory region sequence-specific DNA binding |
IBA |
21873635 |
GO:0000981 |
Function |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ISA |
|
GO:0005634 |
Component |
Nucleus |
IBA |
21873635 |
GO:0006357 |
Process |
Regulation of transcription by RNA polymerase II |
IBA |
21873635 |
GO:0030853 |
Process |
Negative regulation of granulocyte differentiation |
IEA |
|
GO:0045650 |
Process |
Negative regulation of macrophage differentiation |
IEA |
|
GO:0045656 |
Process |
Negative regulation of monocyte differentiation |
IEA |
|
GO:0046872 |
Function |
Metal ion binding |
IEA |
|
GO:2001199 |
Process |
Negative regulation of dendritic cell differentiation |
IEA |
|
GO:2001200 |
Process |
Positive regulation of dendritic cell differentiation |
IEA |
|
|
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|
Protein
|
UniProt ID |
Q86UZ6 |
Protein name |
Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340) |
Protein function |
Functions as a transcriptional repressor for PRDM1. |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00651 |
BTB |
21 → 129 |
BTB/POZ domain |
Domain |
PF13909 |
zf-H2C2_5 |
418 → 442 |
|
Domain |
|
Sequence |
|
Sequence length |
589 |
Interactions |
View interactions |
Associated diseases
|
Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Asthma |
Asthma |
rs324981, rs121912630, rs150116809, rs4950928, rs708494, rs1581842283 |
31619474 |
Multiple sclerosis |
Multiple Sclerosis |
rs104895219, rs483353022, rs483353023, rs483353028, rs483353029, rs483353024, rs483353030, rs3207617, rs483353031, rs483353032, rs483353033, rs483353034, rs483353035, rs483353036, rs483353039, rs483353038, rs61731956, rs568165874, rs767480544 |
31407831, 21833088 |
Osteomyelitis |
Chronic osteomyelitis |
rs11125529, rs10936599, rs7675998, rs398652, rs755017 |
|
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
B-cell lymphoma |
Marginal Zone B-Cell Lymphoma |
|
31407831 |
Eczema |
Eczema |
|
30595370 |
|