GediPNet logo

CRABP1 (cellular retinoic acid binding protein 1)
Gene
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
1381
Gene nameGene Name - the full gene name approved by the HGNC.
Cellular retinoic acid binding protein 1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CRABP1
SynonymsGene synonyms aliases
CRABP, CRABP-I, CRABPI, RBP5
ChromosomeChromosome number
15
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
15q25.1
SummarySummary of gene provided in NCBI Entrez Gene.
This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins,
miRNAmiRNA information provided by mirtarbase database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
miRTarBase ID miRNA Experiments Reference
MIRT018173 hsa-miR-335-5p Microarray 18185580
MIRT907921 hsa-miR-1275 CLIP-seq
MIRT907922 hsa-miR-3117-5p CLIP-seq
MIRT907923 hsa-miR-4447 CLIP-seq
MIRT907924 hsa-miR-4472 CLIP-seq
Transcription factors
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Transcription factor Regulation Reference
EP300 Activation 18000064
RARA Activation 18000064
ZBTB16 Activation 18000064
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0001972 Function Retinoic acid binding IEA
GO:0005501 Function Retinoid binding TAS 1309505
GO:0005515 Function Protein binding IPI 15607035, 32296183
GO:0005829 Component Cytosol TAS
GO:0007165 Process Signal transduction TAS 1309505
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID P29762
Protein name Cellular retinoic acid-binding protein 1 (Cellular retinoic acid-binding protein I) (CRABP-I)
Protein function Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.
PDB 7A9Y , 7A9Z
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00061 Lipocalin
5 → 137
Lipocalin / cytosolic fatty-acid binding protein family
 Domain
Sequence
Sequence length 137
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
 
Reactome
    RA biosynthesis pathway
Associated diseases
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Causal
Disease name Disease term dbSNP ID References
Esophagus neoplasm Squamous cell carcinoma of esophagus rs28934578, rs121918714, rs1567556006, rs1575166666 17438526
Papillary renal carcinoma Papillary Renal Cell Carcinoma rs5030823, rs2137087134, rs121913668, rs121913669, rs121913670, rs121913671, rs121913673, rs121913243, rs786202724 16254461
Renal carcinoma Renal Cell Carcinoma, Conventional (Clear Cell) Renal Cell Carcinoma, Sarcomatoid Renal Cell Carcinoma, Collecting Duct Carcinoma of the Kidney rs121913668, rs121913670, rs121913243, rs786202724 16254461
Unknown
Disease name Disease term dbSNP ID References
Chromophobe carcinoma Chromophobe Renal Cell Carcinoma rs137853247 16254461
Liver neoplasms Liver neoplasms 19233941
Liver cancer Malignant neoplasm of liver 19233941

| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412