GediPNet logo

LETM2 (leucine zipper and EF-hand containing transmembrane protein 2)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
137994
Gene nameGene Name - the full gene name approved by the HGNC.
Leucine zipper and EF-hand containing transmembrane protein 2
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
LETM2
SynonymsGene synonyms aliases
SLC55A2
ChromosomeChromosome number
8
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
8p11.23
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT716072 hsa-miR-4438 HITS-CLIP 19536157
MIRT716071 hsa-miR-455-5p HITS-CLIP 19536157
MIRT716070 hsa-miR-6504-3p HITS-CLIP 19536157
MIRT716069 hsa-miR-619-5p HITS-CLIP 19536157
MIRT716068 hsa-miR-6506-5p HITS-CLIP 19536157
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005743 Component Mitochondrial inner membrane IEA
GO:0006875 Process Cellular metal ion homeostasis IBA 21873635
GO:0016021 Component Integral component of membrane IEA
GO:0043022 Function Ribosome binding IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q2VYF4
Protein name LETM1 domain-containing protein LETM2, mitochondrial (LETM1 and EF-hand domain-containing protein 2) (Leucine zipper-EF-hand-containing transmembrane protein 1-like)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07766 LETM1
122 386
LETM1-like protein
Family
Sequence
MAFYSYNSVLAIARTRFPSHFVHPTCSSYSPSCAFLHLPDSHLNKTCMKNYESKKYSDPS
QPGNTVLHPGTRLIQKLHTSTCWLQEVPGKPQLEQATKHPQVTSPQATKETGMEIKEGKQ
SYRQKIMDELKYYYNGFYLLWIDAKVAARMVWRLLHGQVLTRRERRRLLRTCVDFFRLVP
FMVFLIVPFMEFLLPVFLKLFPEMLPSTFESESKKEEKQKKKMAVKLELAKFLQETMTEM
ARRNRAKMGDASTQLSSYVKQVQTGHKPSTKEIVRFSKLFEDQLALEHLDRPQLVALCKL
LELQTFGTNNLLRFQLLMKLKSIKADDEIIAKEGVTALSVSELQAACRARGMRSLGLTEE
QLRQQLTEWQDLHLKENVPPSLLLLS
RTFYLIDVKPKPIEIPLSGEAPKTDILVELPTFT
ESKENMVDLAPQLKGTKDEDFIQPPPVTSSPITPSTPISLPKGPITSSEEPTLQAKSQMT
AQNSKASSKGA
Sequence length 491
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 30285260, 28991256, 26198764

| © 2021, Biomedical Informatics Centre, NIRRH |
ICMR-National Institute for Research in Reproductive Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Tel: +91-22-24192104, Fax No: +91-22-24139412