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SGCZ (sarcoglycan zeta)
Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
137868
Gene nameGene Name - the full gene name approved by the HGNC.
Sarcoglycan zeta
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
SGCZ
SynonymsGene synonyms aliases
ZSG1
ChromosomeChromosome number
8
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
8p22
SummarySummary of gene provided in NCBI Entrez Gene.
The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single trans
miRNAmiRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
miRTarBase ID miRNA Experiments Reference
MIRT1343015 hsa-miR-380 CLIP-seq
MIRT1343016 hsa-miR-3924 CLIP-seq
MIRT1343017 hsa-miR-4495 CLIP-seq
MIRT1343018 hsa-miR-4646-5p CLIP-seq
MIRT1343019 hsa-miR-4729 CLIP-seq
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0005737 Component Cytoplasm IEA
GO:0005856 Component Cytoskeleton IEA
GO:0016012 Component Sarcoglycan complex IBA 21873635
GO:0016012 Component Sarcoglycan complex TAS 17438352
GO:0016021 Component Integral component of membrane IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q96LD1
Protein name Zeta-sarcoglycan (Zeta-SG) (ZSG1)
Protein function Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. May play a role in the maintenance of striated muscle membrane stability
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04790 Sarcoglycan_1
25 → 286
Sarcoglycan complex subunit protein
 Family
Sequence
Sequence length 299
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
 
KEGG
  
  Cytoskeleton in muscle cells
Hypertrophic cardiomyopathy
Arrhythmogenic right ventricular cardiomyopathy
Dilated cardiomyopathy
Viral myocarditis 		 
Associated diseases
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Causal
Disease name Disease term dbSNP ID References
Cholelithiasis Cholelithiasis rs121918440, rs72552778, rs387906528, rs759202962, rs377160065, rs1051861187, rs757693457, rs752563752 17632509
Hypertension Hypertensive disease rs13306026, rs13333226 27802415, 28498854
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297, rs11978267, rs4132601 27903959
Rheumatoid arthritis Rheumatoid Arthritis rs3766379, rs3792876, rs2071592, rs3087456, rs587776843, rs1566328963, rs2240340, rs1557787212 31596875
Unknown
Disease name Disease term dbSNP ID References
Anxiety disorder Anxiety 29942085
Cholecystolithiasis Cholecystolithiasis 17632509
Dermatologic disorders Dermatologic disorders 28720099
Panic disorder Panic Disorder 19165232

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