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CPA2 (carboxypeptidase A2)
Gene
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
1358
Gene nameGene Name - the full gene name approved by the HGNC.
Carboxypeptidase A2
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CPA2
SynonymsGene synonyms aliases
-
ChromosomeChromosome number
7
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7q32.2
SummarySummary of gene provided in NCBI Entrez Gene.
Three different forms of human pancreatic procarboxypeptidase A have been isolated. The encoded protein represents the A2 form, which is a monomeric protein with different biochemical properties from the A1 and A3 forms. The A2 form of pancreatic procarbo
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0004180 Function Carboxypeptidase activity IDA 2920728
GO:0004181 Function Metallocarboxypeptidase activity IBA 21873635
GO:0004181 Function Metallocarboxypeptidase activity IDA 2920728
GO:0005576 Component Extracellular region IDA 2920728
GO:0005615 Component Extracellular space IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID P48052
Protein name Carboxypeptidase A2 (EC 3.4.17.15)
Protein function Carboxypeptidase that catalyzes the release of a C-terminal amino acid, with a preference for large aromatic C-terminal residues.
PDB 1AYE , 1DTD , 1O6X
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02244 Propep_M14
28 → 102
Carboxypeptidase activation peptide
 Domain
PF00246 Peptidase_M14
129 → 406
Zinc carboxypeptidase
 Domain
Sequence
Sequence length 419
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
 
KEGG
  
  Pancreatic secretion
Protein digestion and absorption 		 
Associated diseases
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Causal
Disease name Disease term dbSNP ID References
Lymphoblastic leukemia Precursor Cell Lymphoblastic Leukemia Lymphoma rs387906351, rs104894562, rs398122513, rs398122840, rs398123063, rs1057524466, rs1064796115, rs1064795660, rs1064793129, rs1064796227, rs1567887558, rs1161194345, rs1597558200, rs1406320425, rs1597566470, rs1597566699, rs1597567692, rs1597567985, rs1438890364, rs1288977950, rs1597552140, rs1597566356, rs1597566726, rs1597568117, rs2069719445, rs2069729948, rs2070018439, rs745708044, rs1169577591 27114598

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