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TAAR1 (trace amine associated receptor 1)
Gene
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
134864
Gene nameGene Name - the full gene name approved by the HGNC.
Trace amine associated receptor 1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
TAAR1
SynonymsGene synonyms aliases
TA1, TAR1, TRAR1
ChromosomeChromosome number
6
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6q23.2
SummarySummary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is a G-protein coupled receptor activated by trace amines. The encoded protein responds little or not at all to dopamine, serotonin, epinephrine, or histamine, but responds well to beta-phenylethylamine, p-tyramine, octopa
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0001594 Function Trace-amine receptor activity IBA 21873635
GO:0004930 Function G protein-coupled receptor activity IDA 11723224
GO:0005886 Component Plasma membrane TAS
GO:0007186 Process G protein-coupled receptor signaling pathway TAS
GO:0016021 Component Integral component of membrane IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q96RJ0
Protein name Trace amine-associated receptor 1 (TaR-1) (Trace amine receptor 1)
Protein function Intracellular G-protein coupled receptor for trace amines, which recognizes endogenous amine-containing metabolites such as beta-phenylethylamine (beta-PEA), 3-iodothyronamine (T1AM), isoamylamine (IAA), cadaverine (CAD), cyclohexylamine (CHA),
PDB 8JLN , 8JLO , 8JLP , 8JLQ , 8JLR , 8JSO , 8UHB , 8W87 , 8W88 , 8W89 , 8W8A , 8WC8 , 8WCA , 8ZSJ , 8ZSP , 8ZSS , 9JKQ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00001 7tm_1
40 → 304
7 transmembrane receptor (rhodopsin family)
 Family
Sequence
Sequence length 339
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
 
KEGG
  
Reactome
  Neuroactive ligand-receptor interaction   Amine ligand-binding receptors
G alpha (s) signalling events
ADORA2B mediated anti-inflammatory cytokines production
Associated diseases
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Causal
Disease name Disease term dbSNP ID References
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 22641180

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