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UBE2QL1 (ubiquitin conjugating enzyme E2 QL1)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
134111
Gene nameGene Name - the full gene name approved by the HGNC.
Ubiquitin conjugating enzyme E2 QL1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
UBE2QL1
SynonymsGene synonyms aliases
-
ChromosomeChromosome number
5
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5p15.31
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT621680 hsa-miR-4289 HITS-CLIP 23824327
MIRT621679 hsa-miR-6758-3p HITS-CLIP 23824327
MIRT621678 hsa-miR-1296-5p HITS-CLIP 23824327
MIRT621677 hsa-miR-2909 HITS-CLIP 23824327
MIRT621680 hsa-miR-4289 HITS-CLIP 23824327
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000209 Process Protein polyubiquitination IBA 21873635
GO:0005515 Function Protein binding IPI 24000165
GO:0005524 Function ATP binding IEA
GO:0005634 Component Nucleus IBA 21873635
GO:0005634 Component Nucleus IDA 24000165
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID A1L167
Protein name Ubiquitin-conjugating enzyme E2Q-like protein 1 (EC 2.3.2.23) (E2Q-like ubiquitin-conjugating enzyme 1)
Protein function Probable E2 ubiquitin-protein ligase that catalyzes the covalent attachment of ubiquitin to target proteins. May facilitate the monoubiquitination and degradation of MTOR and CCNE1 through interaction with FBXW7.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00179 UQ_con
1 149
Ubiquitin-conjugating enzyme
Domain
Sequence
Sequence length 161
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
KEGG
 
  Ubiquitin mediated proteolysis  
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Asthma Asthma rs324981, rs121912630, rs150116809, rs4950928, rs708494, rs1581842283 23181788

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