RTP1 (receptor transporter protein 1)

Gene

• Entrez ID: 132112
• Gene name: Receptor transporter protein 1
• Gene symbol: RTP1
• Synonyms: Z3CXXC1
• Chromosome: 3
• Chromosome location: 3q27.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017895	hsa-miR-335-5p	Microarray	18185580
MIRT1322361	hsa-miR-1303	CLIP-seq
MIRT1322362	hsa-miR-2355-5p	CLIP-seq
MIRT1322363	hsa-miR-3180-5p	CLIP-seq
MIRT1322364	hsa-miR-4312	CLIP-seq
MIRT1322365	hsa-miR-4325	CLIP-seq
MIRT1322366	hsa-miR-4477b	CLIP-seq
MIRT1322367	hsa-miR-4735-5p	CLIP-seq
MIRT1322368	hsa-miR-520a-5p	CLIP-seq
MIRT1322369	hsa-miR-525-5p	CLIP-seq
MIRT2095665	hsa-miR-1207-5p	CLIP-seq
MIRT2095666	hsa-miR-1909	CLIP-seq
MIRT2095667	hsa-miR-3184	CLIP-seq
MIRT2095668	hsa-miR-423-5p	CLIP-seq
MIRT2095669	hsa-miR-4251	CLIP-seq
MIRT2095670	hsa-miR-4663	CLIP-seq
MIRT2095671	hsa-miR-4686	CLIP-seq
MIRT2095672	hsa-miR-4688	CLIP-seq
MIRT1322367	hsa-miR-4735-5p	CLIP-seq
MIRT2095673	hsa-miR-4763-3p	CLIP-seq
MIRT2095674	hsa-miR-486-3p	CLIP-seq
MIRT2095675	hsa-miR-580	CLIP-seq
MIRT2393951	hsa-miR-4272	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001580	Process	Detection of chemical stimulus involved in sensory perception of bitter taste	IBA	21873635
GO:0005886	Component	Plasma membrane	IEA
GO:0006612	Process	Protein targeting to membrane	IBA	21873635
GO:0009986	Component	Cell surface	IBA	21873635
GO:0009986	Component	Cell surface	IDA	15550249
GO:0016021	Component	Integral component of membrane	IEA
GO:0031849	Function	Olfactory receptor binding	IBA	21873635
GO:0031849	Function	Olfactory receptor binding	IMP	15550249
GO:0051205	Process	Protein insertion into membrane	IBA	21873635
GO:0051205	Process	Protein insertion into membrane	IDA	15550249

Other IDs

• MIM: 609137
• HGNC: 28580
• e!Ensembl: ENSG00000175077

Protein

• UniProt ID: P59025
• Protein name: Receptor-transporting protein 1 (3CxxC-type zinc finger protein 1)
• Protein function: Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13695	zf-3CxxC	87 → 197	Zinc-binding domain	Domain

• Sequence:

  MRIFRPWRLRCPALHLPSLSVFSLRWKLPSLTTDETMCKSVTTDEWKKVFYEKMEEAKPA
  DSWDLIIDPNLKHNVLSPGWKQYLELHASGRFHCSWCWHTWQSPYVVILFHMFLDRAQRA
  GSVRMRVFKQLCYECGTARLDESSMLEENIEGLVDNLITSLREQCYGERGGQYRIHVASR
  QDNRRHRGEFCEACQEGIVHWKPSEKLLEEEATTYTFSRAPSPTKSQDQTGSGWNFCSIP
  WCLFWATVLLLIIYLQFSFRSSV

• Sequence length: 263

Pathways

Reactome:

Olfactory Signaling Pathway

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158, rs80357524, rs80357115, rs80357945, rs80357729, rs80357609, rs80357259, rs80357981, rs80358063, rs80357389, rs80356862, rs80359876, rs80357580, rs80358053, rs80358089, rs80187739, rs397507241, rs80358069, rs80357590, rs80357284, rs80357941, rs80359261, rs80359272, rs80359276, rs276174813, rs80358474, rs80359316, rs1555282969, rs80359388, rs80359499, rs80359505, rs80359520, rs80359526, rs80359533, rs56253082, rs80358824, rs80359554, rs80359636, rs80359651, rs80359659, rs80359011, rs80359012, rs80359013, rs80359718, rs397507410, rs81002812, rs80359730, rs80359152, rs80359159, rs397507419, rs28897759, rs80359211, rs80359775, rs397514577, rs397507584, rs80358435, rs80358456, rs80359340, rs80359343, rs80359365, rs80358579, rs397507670, rs80358593, rs80359406, rs80359444, rs80359454, rs276174853, rs276174854, rs80359483, rs80359537, rs80358815, rs80358843, rs80359558, rs80359560, rs80359594, rs80358893, rs28897743, rs397507900, rs397507906, rs397507918, rs80358971, rs80358981, rs397507941, rs80359030, rs80359035, rs41293511, rs397507396, rs81002806, rs80359112, rs397508006, rs81002893, rs45580035, rs80359760, rs397508051, rs80359772, rs4987049, rs80359777, rs80357770, rs397508867, rs62625303, rs397508874, rs80357506, rs80357287, rs273898674, rs80358042, rs80358083, rs80357058, rs41286296, rs80357960, rs80356945, rs80357223, rs386134270, rs80358116, rs80357856, rs80357424, rs397509050, rs80357485, rs80357966, rs397509067, rs80357310, rs80356866, rs80357260, rs80357437, rs80358023, rs80358086, rs80357133, rs80356993, rs80357997, rs80357239, rs80357227, rs397509243, rs80356969, rs80356959, rs63750617, rs63751319, rs587779315, rs200640585, rs398122546, rs80357543, rs398122687, rs80359328, rs398122779, rs398122783, rs62517194, rs80358029, rs515726060, rs180177103, rs180177111, rs180177133, rs587776527, rs180177135, rs180177136, rs515726117, rs587779813, rs587779909, rs587780024, rs587780100, rs28909982, rs121908698, rs180177100, rs587780210, rs587780240, rs587780639, rs587781269, rs587781353, rs587781471, rs587781658, rs587781697, rs587781730, rs587781894, rs587781948, rs587782005, rs587782011, rs200928781, rs587781558, rs370228071, rs587782245, rs587782401, rs180177110, rs587782504, rs72552322, rs587782531, rs587782620, rs587782680, rs587782774, rs587782818, rs730881411, rs730881389, rs564652222, rs397507768, rs587776419, rs730881868, rs730881940, rs56383036, rs758972589, rs201089102, rs730881348, rs786202608, rs786201886, rs786203318, rs786203775, rs786203714, rs786202033, rs750621215, rs786203884, rs786203650, rs772821016, rs863224521, rs864622223, rs864622655, rs375699023, rs876659572, rs768362387, rs876659535, rs876658957, rs483353072, rs876659435, rs267608041, rs876661113, rs730881369, rs878853535, rs772228129, rs878855122, rs760551339, rs80359596, rs397509222, rs886039630, rs886039683, rs886040828, rs587781799, rs886040374, rs886040649, rs397507967, rs878854957, rs886040043, rs1057517589, rs1060502769, rs866380588, rs863224765, rs1064793243, rs747563556, rs1555074976, rs1064795885, rs753961188, rs1064794708, rs869312772, rs1064793887, rs1131690820, rs1135401928, rs1135401868, rs1135401859, rs1553370324, rs397507630, rs1555283160, rs1555283251, rs1555283262, rs1555283361, rs1555286298, rs1555288462, rs886040950, rs1555289566, rs776323117, rs80357123, rs1555579627, rs1555580697, rs80358054, rs1555593302, rs1328985852, rs763470424, rs1555139694, rs878854697, rs1555461217, rs1555461765, rs774684620, rs766416564, rs1554558613, rs1305740166, rs1555461460, rs1555461407, rs1555461586, rs1555567202, rs1555607022, rs1555069815, rs1442299125, rs1474786480, rs1555084947, rs1555457867, rs141087784, rs1482641121, rs1564830522, rs1565469955, rs1565503137, rs864622613, rs755263466, rs757679199, rs1593903166, rs1597801649, rs1603293306, rs879253880, rs80358754, rs1597062038, rs45494092, rs1603275367, rs887358871, rs1597091518, rs1966967065, rs1064793049, rs2082872908, rs2085078278, rs2072475243