FAM131A (family with sequence similarity 131 member A)

Gene

• Entrez ID: 131408
• Gene name: Family with sequence similarity 131 member A
• Gene symbol: FAM131A
• Synonyms: C3orf40, FLAT715, PRO1378
• Chromosome: 3
• Chromosome location: 3q27.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT052028	hsa-let-7b-5p	CLASH	23622248
MIRT979993	hsa-miR-1257	CLIP-seq
MIRT979994	hsa-miR-3194-3p	CLIP-seq
MIRT979995	hsa-miR-3919	CLIP-seq
MIRT979996	hsa-miR-4520a-5p	CLIP-seq
MIRT979997	hsa-miR-4520b-5p	CLIP-seq
MIRT979998	hsa-miR-4756-3p	CLIP-seq
MIRT979999	hsa-miR-4790-3p	CLIP-seq
MIRT1990341	hsa-miR-3120-5p	CLIP-seq
MIRT1990342	hsa-miR-1251	CLIP-seq
MIRT1990343	hsa-miR-1291	CLIP-seq
MIRT1990344	hsa-miR-3183	CLIP-seq
MIRT1990345	hsa-miR-328	CLIP-seq
MIRT1990346	hsa-miR-4474-3p	CLIP-seq
MIRT1990347	hsa-miR-4723-3p	CLIP-seq
MIRT1990348	hsa-miR-581	CLIP-seq
MIRT1990349	hsa-miR-663b	CLIP-seq
MIRT979993	hsa-miR-1257	CLIP-seq
MIRT2224556	hsa-miR-3137	CLIP-seq
MIRT2224557	hsa-miR-4690-3p	CLIP-seq
MIRT2224558	hsa-miR-4717-3p	CLIP-seq
MIRT2224559	hsa-miR-4802-3p	CLIP-seq
MIRT2449132	hsa-miR-3121-3p	CLIP-seq
MIRT2449133	hsa-miR-4773	CLIP-seq
MIRT1990349	hsa-miR-663b	CLIP-seq

Other IDs

• MIM: HGNC
• e!Ensembl: HGNC

Protein

• UniProt ID: Q6UXB0
• Protein name: Protein FAM131A
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15010	FAM131	80 → 358	Putative cell signalling	Family

• Sequence:

  MPMISVLGKMFLWQREGPGGRWTCQTSRRVSSDPAWAVEWIELPRGLSLSSLGSARTLRG
  WSRSSRPSSVDSQDLPEVNVGDTVAMLPKSRRALTIQEIAALARSSLHGISQVVKDHVTK
  PTAMAQGRVAHLIEWKGWSKPSDSPAALESAFSSYSDLSEGEQEARFAAGVAEQFAIAEA
  KLRAWSSVDGEDSTDDSYDEDFAGGMDTDMAGQLPLGPHLQDLFTGHRFSRPVRQGSVEP
  ESDCSQTVSPDTLCSSLCSLEDGLLGSPARLASQLLGDELLLAKLPPSRESAFRSLGPLE
  AQDSLYNSPLTESCLSPAEEEPAPCKDCQPLCPPLTGSWERQRQASDLASSGVVSLDEDE
  AEPEEQ

• Sequence length: 366

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158, rs80357524, rs80357115, rs80357945, rs80357729, rs80357609, rs80357259, rs80357981, rs80358063, rs80357389, rs80356862, rs80359876, rs80357580, rs80358053, rs80358089, rs80187739, rs397507241, rs80358069, rs80357590, rs80357284, rs80357941, rs80359261, rs80359272, rs80359276, rs276174813, rs80358474, rs80359316, rs1555282969, rs80359388, rs80359499, rs80359505, rs80359520, rs80359526, rs80359533, rs56253082, rs80358824, rs80359554, rs80359636, rs80359651, rs80359659, rs80359011, rs80359012, rs80359013, rs80359718, rs397507410, rs81002812, rs80359730, rs80359152, rs80359159, rs397507419, rs28897759, rs80359211, rs80359775, rs397514577, rs397507584, rs80358435, rs80358456, rs80359340, rs80359343, rs80359365, rs80358579, rs397507670, rs80358593, rs80359406, rs80359444, rs80359454, rs276174853, rs276174854, rs80359483, rs80359537, rs80358815, rs80358843, rs80359558, rs80359560, rs80359594, rs80358893, rs28897743, rs397507900, rs397507906, rs397507918, rs80358971, rs80358981, rs397507941, rs80359030, rs80359035, rs41293511, rs397507396, rs81002806, rs80359112, rs397508006, rs81002893, rs45580035, rs80359760, rs397508051, rs80359772, rs4987049, rs80359777, rs80357770, rs397508867, rs62625303, rs397508874, rs80357506, rs80357287, rs273898674, rs80358042, rs80358083, rs80357058, rs41286296, rs80357960, rs80356945, rs80357223, rs386134270, rs80358116, rs80357856, rs80357424, rs397509050, rs80357485, rs80357966, rs397509067, rs80357310, rs80356866, rs80357260, rs80357437, rs80358023, rs80358086, rs80357133, rs80356993, rs80357997, rs80357239, rs80357227, rs397509243, rs80356969, rs80356959, rs63750617, rs63751319, rs587779315, rs200640585, rs398122546, rs80357543, rs398122687, rs80359328, rs398122779, rs398122783, rs62517194, rs80358029, rs515726060, rs180177103, rs180177111, rs180177133, rs587776527, rs180177135, rs180177136, rs515726117, rs587779813, rs587779909, rs587780024, rs587780100, rs28909982, rs121908698, rs180177100, rs587780210, rs587780240, rs587780639, rs587781269, rs587781353, rs587781471, rs587781658, rs587781697, rs587781730, rs587781894, rs587781948, rs587782005, rs587782011, rs200928781, rs587781558, rs370228071, rs587782245, rs587782401, rs180177110, rs587782504, rs72552322, rs587782531, rs587782620, rs587782680, rs587782774, rs587782818, rs730881411, rs730881389, rs564652222, rs397507768, rs587776419, rs730881868, rs730881940, rs56383036, rs758972589, rs201089102, rs730881348, rs786202608, rs786201886, rs786203318, rs786203775, rs786203714, rs786202033, rs750621215, rs786203884, rs786203650, rs772821016, rs863224521, rs864622223, rs864622655, rs375699023, rs876659572, rs768362387, rs876659535, rs876658957, rs483353072, rs876659435, rs267608041, rs876661113, rs730881369, rs878853535, rs772228129, rs878855122, rs760551339, rs80359596, rs397509222, rs886039630, rs886039683, rs886040828, rs587781799, rs886040374, rs886040649, rs397507967, rs878854957, rs886040043, rs1057517589, rs1060502769, rs866380588, rs863224765, rs1064793243, rs747563556, rs1555074976, rs1064795885, rs753961188, rs1064794708, rs869312772, rs1064793887, rs1131690820, rs1135401928, rs1135401868, rs1135401859, rs1553370324, rs397507630, rs1555283160, rs1555283251, rs1555283262, rs1555283361, rs1555286298, rs1555288462, rs886040950, rs1555289566, rs776323117, rs80357123, rs1555579627, rs1555580697, rs80358054, rs1555593302, rs1328985852, rs763470424, rs1555139694, rs878854697, rs1555461217, rs1555461765, rs774684620, rs766416564, rs1554558613, rs1305740166, rs1555461460, rs1555461407, rs1555461586, rs1555567202, rs1555607022, rs1555069815, rs1442299125, rs1474786480, rs1555084947, rs1555457867, rs141087784, rs1482641121, rs1564830522, rs1565469955, rs1565503137, rs864622613, rs755263466, rs757679199, rs1593903166, rs1597801649, rs1603293306, rs879253880, rs80358754, rs1597062038, rs45494092, rs1603275367, rs887358871, rs1597091518, rs1966967065, rs1064793049, rs2082872908, rs2085078278, rs2072475243
Hyperaldosteronism	Hyperaldosteronism, Familial, Type II	rs28934586, rs104894068, rs387906778, rs386352319, rs587777437, rs587777438, rs587777439, rs786205050, rs771507094, rs1085307938, rs1553853557, rs1553856214, rs1293789661, rs1553857113, rs758379595
Hypertension	Hypertensive disease	rs13306026, rs13333226

Unknown
Disease name	Disease term	dbSNP ID	References
Conn syndrome	Conn Syndrome
Glucocortocoid-insensitive hyperaldosteronism	Glucocortocoid-insensitive primary hyperaldosteronism