Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
130507 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
Ubiquitin protein ligase E3 component n-recognin 3 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
UBR3 |
SynonymsGene synonyms aliases
|
ZNF650 |
ChromosomeChromosome number
|
2 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
2q31.1 |
miRNAmiRNA information provided by mirtarbase database.
|
|
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
|
|
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|
Protein
|
UniProt ID |
Q6ZT12 |
Protein name |
E3 ubiquitin-protein ligase UBR3 (EC 2.3.2.27) (N-recognin-3) (RING-type E3 ubiquitin transferase UBR3) (Ubiquitin-protein ligase E3-alpha-3) (Ubiquitin-protein ligase E3-alpha-III) (Zinc finger protein 650) |
Protein function |
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway (By similarity). Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and su |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF02207 |
zf-UBR |
119 → 187 |
Putative zinc finger in N-recognin (UBR box) |
Family |
PF18995 |
PRT6_C |
1423 → 1871 |
Proteolysis_6 C-terminal |
Domain |
|
Sequence |
|
Sequence length |
1888 |
Interactions |
View interactions |
Associated diseases
|
|