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CNP (2'',3''-cyclic nucleotide 3'' phosphodiesterase)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
1267
Gene nameGene Name - the full gene name approved by the HGNC.
2'',3''-cyclic nucleotide 3'' phosphodiesterase
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CNP
SynonymsGene synonyms aliases
CN37, CNP1, HLD20
ChromosomeChromosome number
17
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17q21.2
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT022857 hsa-miR-124-3p Proteomics;Microarray 18668037
MIRT051255 hsa-miR-16-5p CLASH 23622248
MIRT049951 hsa-miR-30a-5p CLASH 23622248
MIRT042728 hsa-miR-345-5p CLASH 23622248
MIRT040114 hsa-miR-615-3p CLASH 23622248
Transcription factors
Transcription factor Regulation Reference
TSC22D1 Activation 20802130
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000226 Process Microtubule cytoskeleton organization IEA
GO:0003723 Function RNA binding IEA
GO:0004113 Function 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity IBA 21873635
GO:0005515 Function Protein binding IPI 17500595, 32814053
GO:0005615 Component Extracellular space IDA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID P09543
Protein name 2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) (CNPase) (EC 3.1.4.37)
Protein function Catalyzes the formation of 2'-nucleotide products from 2',3'-cyclic substrates (By similarity). May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin (By similarity). {
PDB 1WOJ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13671 AAA_33
52 175
Domain
PF05881 CNPase
186 420
Family
Sequence
Sequence length 421
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Schizophrenia Schizophrenia rs74315508, rs74315509, rs13447324, rs1558507406, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313 18289148, 17964117, 23032943, 24788877, 19348671
Unknown
Disease name Disease term dbSNP ID References
Mental depression Unipolar Depression, Major Depressive Disorder rs587778876, rs587778877 22832658

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