CNTD1 (cyclin N-terminal domain containing 1)

Gene

• Entrez ID: 124817
• Gene name: Cyclin N-terminal domain containing 1
• Gene symbol: CNTD1
• Synonyms: CNTD, COSA1
• Chromosome: 17
• Chromosome location: 17q21.2-q21.31

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT901498	hsa-miR-125a-5p	CLIP-seq
MIRT901499	hsa-miR-125b	CLIP-seq
MIRT901500	hsa-miR-129-3p	CLIP-seq
MIRT901501	hsa-miR-3134	CLIP-seq
MIRT901502	hsa-miR-3189-3p	CLIP-seq
MIRT901503	hsa-miR-3198	CLIP-seq
MIRT901504	hsa-miR-3607-5p	CLIP-seq
MIRT901505	hsa-miR-409-3p	CLIP-seq
MIRT901506	hsa-miR-4309	CLIP-seq
MIRT901507	hsa-miR-4319	CLIP-seq
MIRT901508	hsa-miR-432	CLIP-seq
MIRT901509	hsa-miR-4446-5p	CLIP-seq
MIRT901510	hsa-miR-4534	CLIP-seq
MIRT901511	hsa-miR-4540	CLIP-seq
MIRT901512	hsa-miR-4661-3p	CLIP-seq
MIRT901513	hsa-miR-4732-3p	CLIP-seq
MIRT901514	hsa-miR-4755-5p	CLIP-seq
MIRT901515	hsa-miR-4786-3p	CLIP-seq
MIRT901516	hsa-miR-554	CLIP-seq
MIRT901517	hsa-miR-619	CLIP-seq
MIRT901518	hsa-miR-670	CLIP-seq
MIRT1967423	hsa-miR-1267	CLIP-seq
MIRT1967424	hsa-miR-1278	CLIP-seq
MIRT1967425	hsa-miR-1303	CLIP-seq
MIRT1967426	hsa-miR-3149	CLIP-seq
MIRT1967427	hsa-miR-3192	CLIP-seq
MIRT1967428	hsa-miR-3662	CLIP-seq
MIRT1967429	hsa-miR-4314	CLIP-seq
MIRT1967430	hsa-miR-4646-5p	CLIP-seq
MIRT1967431	hsa-miR-4652-3p	CLIP-seq
MIRT1967432	hsa-miR-4738-3p	CLIP-seq
MIRT1967433	hsa-miR-4778-5p	CLIP-seq
MIRT1967434	hsa-miR-630	CLIP-seq
MIRT1967435	hsa-miR-653	CLIP-seq
MIRT1967425	hsa-miR-1303	CLIP-seq
MIRT2203097	hsa-miR-3152-3p	CLIP-seq
MIRT2203098	hsa-miR-3194-3p	CLIP-seq
MIRT2203099	hsa-miR-4431	CLIP-seq
MIRT2203100	hsa-miR-4522	CLIP-seq
MIRT2203101	hsa-miR-767-3p	CLIP-seq
MIRT1967426	hsa-miR-3149	CLIP-seq
MIRT1967427	hsa-miR-3192	CLIP-seq
MIRT1967429	hsa-miR-4314	CLIP-seq
MIRT1967430	hsa-miR-4646-5p	CLIP-seq
MIRT1967433	hsa-miR-4778-5p	CLIP-seq
MIRT1967434	hsa-miR-630	CLIP-seq
MIRT1967423	hsa-miR-1267	CLIP-seq
MIRT1967425	hsa-miR-1303	CLIP-seq
MIRT1967431	hsa-miR-4652-3p	CLIP-seq
MIRT1967432	hsa-miR-4738-3p	CLIP-seq
MIRT1967433	hsa-miR-4778-5p	CLIP-seq
MIRT1967435	hsa-miR-653	CLIP-seq
MIRT2447373	hsa-miR-1185	CLIP-seq
MIRT2447374	hsa-miR-1202	CLIP-seq
MIRT2447375	hsa-miR-1261	CLIP-seq
MIRT2447376	hsa-miR-1273f	CLIP-seq
MIRT2447377	hsa-miR-143	CLIP-seq
MIRT2447378	hsa-miR-190	CLIP-seq
MIRT2447379	hsa-miR-190b	CLIP-seq
MIRT2447380	hsa-miR-204	CLIP-seq
MIRT2447381	hsa-miR-2052	CLIP-seq
MIRT2447382	hsa-miR-211	CLIP-seq
MIRT2447383	hsa-miR-223	CLIP-seq
MIRT2447384	hsa-miR-299-3p	CLIP-seq
MIRT2447385	hsa-miR-3153	CLIP-seq
MIRT2447386	hsa-miR-3180-5p	CLIP-seq
MIRT2447387	hsa-miR-3194-5p	CLIP-seq
MIRT2447388	hsa-miR-3201	CLIP-seq
MIRT2447389	hsa-miR-3605-5p	CLIP-seq
MIRT2447390	hsa-miR-3679-5p	CLIP-seq
MIRT2447391	hsa-miR-3972	CLIP-seq
MIRT2447392	hsa-miR-4307	CLIP-seq
MIRT2447393	hsa-miR-4328	CLIP-seq
MIRT901509	hsa-miR-4446-5p	CLIP-seq
MIRT2447394	hsa-miR-4648	CLIP-seq
MIRT2447395	hsa-miR-4654	CLIP-seq
MIRT2447396	hsa-miR-4668-5p	CLIP-seq
MIRT2447397	hsa-miR-4708-5p	CLIP-seq
MIRT901514	hsa-miR-4755-5p	CLIP-seq
MIRT2447398	hsa-miR-4769-5p	CLIP-seq
MIRT2447399	hsa-miR-4770	CLIP-seq
MIRT2447400	hsa-miR-4791	CLIP-seq
MIRT2447401	hsa-miR-520a-5p	CLIP-seq
MIRT2447402	hsa-miR-525-5p	CLIP-seq
MIRT2447403	hsa-miR-623	CLIP-seq
MIRT2447373	hsa-miR-1185	CLIP-seq
MIRT2447374	hsa-miR-1202	CLIP-seq
MIRT2447376	hsa-miR-1273f	CLIP-seq
MIRT2447377	hsa-miR-143	CLIP-seq
MIRT2447378	hsa-miR-190	CLIP-seq
MIRT2447379	hsa-miR-190b	CLIP-seq
MIRT2447380	hsa-miR-204	CLIP-seq
MIRT2447381	hsa-miR-2052	CLIP-seq
MIRT2447382	hsa-miR-211	CLIP-seq
MIRT2447383	hsa-miR-223	CLIP-seq
MIRT2447386	hsa-miR-3180-5p	CLIP-seq
MIRT2447387	hsa-miR-3194-5p	CLIP-seq
MIRT2447388	hsa-miR-3201	CLIP-seq
MIRT2447389	hsa-miR-3605-5p	CLIP-seq
MIRT2447390	hsa-miR-3679-5p	CLIP-seq
MIRT2447391	hsa-miR-3972	CLIP-seq
MIRT2447392	hsa-miR-4307	CLIP-seq
MIRT2447393	hsa-miR-4328	CLIP-seq
MIRT901509	hsa-miR-4446-5p	CLIP-seq
MIRT2447397	hsa-miR-4708-5p	CLIP-seq
MIRT901514	hsa-miR-4755-5p	CLIP-seq
MIRT2447399	hsa-miR-4770	CLIP-seq
MIRT2447400	hsa-miR-4791	CLIP-seq
MIRT2447401	hsa-miR-520a-5p	CLIP-seq
MIRT2447402	hsa-miR-525-5p	CLIP-seq
MIRT2447403	hsa-miR-623	CLIP-seq
MIRT2447373	hsa-miR-1185	CLIP-seq
MIRT2447374	hsa-miR-1202	CLIP-seq
MIRT2506117	hsa-miR-1245b-3p	CLIP-seq
MIRT2447375	hsa-miR-1261	CLIP-seq
MIRT2506118	hsa-miR-1273e	CLIP-seq
MIRT2447376	hsa-miR-1273f	CLIP-seq
MIRT2506119	hsa-miR-141	CLIP-seq
MIRT2447377	hsa-miR-143	CLIP-seq
MIRT2447378	hsa-miR-190	CLIP-seq
MIRT2447379	hsa-miR-190b	CLIP-seq
MIRT2506120	hsa-miR-200a	CLIP-seq
MIRT2506121	hsa-miR-203	CLIP-seq
MIRT2447380	hsa-miR-204	CLIP-seq
MIRT2447381	hsa-miR-2052	CLIP-seq
MIRT2447382	hsa-miR-211	CLIP-seq
MIRT2447383	hsa-miR-223	CLIP-seq
MIRT2447384	hsa-miR-299-3p	CLIP-seq
MIRT2506122	hsa-miR-3129-3p	CLIP-seq
MIRT2506123	hsa-miR-3140-3p	CLIP-seq
MIRT2447385	hsa-miR-3153	CLIP-seq
MIRT2447386	hsa-miR-3180-5p	CLIP-seq
MIRT2447387	hsa-miR-3194-5p	CLIP-seq
MIRT2447388	hsa-miR-3201	CLIP-seq
MIRT2447389	hsa-miR-3605-5p	CLIP-seq
MIRT901504	hsa-miR-3607-5p	CLIP-seq
MIRT2447390	hsa-miR-3679-5p	CLIP-seq
MIRT2506124	hsa-miR-383	CLIP-seq
MIRT2506125	hsa-miR-3913-3p	CLIP-seq
MIRT2506126	hsa-miR-3921	CLIP-seq
MIRT2447391	hsa-miR-3972	CLIP-seq
MIRT2447392	hsa-miR-4307	CLIP-seq
MIRT2447393	hsa-miR-4328	CLIP-seq
MIRT901509	hsa-miR-4446-5p	CLIP-seq
MIRT2447394	hsa-miR-4648	CLIP-seq
MIRT2506127	hsa-miR-4653-5p	CLIP-seq
MIRT2447395	hsa-miR-4654	CLIP-seq
MIRT2506128	hsa-miR-4659a-3p	CLIP-seq
MIRT2506129	hsa-miR-4659b-3p	CLIP-seq
MIRT2447396	hsa-miR-4668-5p	CLIP-seq
MIRT2447397	hsa-miR-4708-5p	CLIP-seq
MIRT2506130	hsa-miR-4735-5p	CLIP-seq
MIRT901514	hsa-miR-4755-5p	CLIP-seq
MIRT2506131	hsa-miR-4766-5p	CLIP-seq
MIRT2447398	hsa-miR-4769-5p	CLIP-seq
MIRT2447399	hsa-miR-4770	CLIP-seq
MIRT2506132	hsa-miR-4772-5p	CLIP-seq
MIRT2447400	hsa-miR-4791	CLIP-seq
MIRT2506133	hsa-miR-489	CLIP-seq
MIRT2506134	hsa-miR-513a-3p	CLIP-seq
MIRT2447401	hsa-miR-520a-5p	CLIP-seq
MIRT2447402	hsa-miR-525-5p	CLIP-seq
MIRT2506135	hsa-miR-548ae	CLIP-seq
MIRT2506136	hsa-miR-548aj	CLIP-seq
MIRT2506137	hsa-miR-548am	CLIP-seq
MIRT2506138	hsa-miR-548x	CLIP-seq
MIRT901517	hsa-miR-619	CLIP-seq
MIRT2447403	hsa-miR-623	CLIP-seq
MIRT2506139	hsa-miR-942	CLIP-seq
MIRT2447373	hsa-miR-1185	CLIP-seq
MIRT2447374	hsa-miR-1202	CLIP-seq
MIRT2506117	hsa-miR-1245b-3p	CLIP-seq
MIRT2447375	hsa-miR-1261	CLIP-seq
MIRT2506118	hsa-miR-1273e	CLIP-seq
MIRT2447376	hsa-miR-1273f	CLIP-seq
MIRT2447377	hsa-miR-143	CLIP-seq
MIRT2447378	hsa-miR-190	CLIP-seq
MIRT2447379	hsa-miR-190b	CLIP-seq
MIRT2506121	hsa-miR-203	CLIP-seq
MIRT2447380	hsa-miR-204	CLIP-seq
MIRT2447381	hsa-miR-2052	CLIP-seq
MIRT2447382	hsa-miR-211	CLIP-seq
MIRT2447383	hsa-miR-223	CLIP-seq
MIRT2447384	hsa-miR-299-3p	CLIP-seq
MIRT2506122	hsa-miR-3129-3p	CLIP-seq
MIRT2506123	hsa-miR-3140-3p	CLIP-seq
MIRT2447386	hsa-miR-3180-5p	CLIP-seq
MIRT2447387	hsa-miR-3194-5p	CLIP-seq
MIRT2447388	hsa-miR-3201	CLIP-seq
MIRT2447389	hsa-miR-3605-5p	CLIP-seq
MIRT901504	hsa-miR-3607-5p	CLIP-seq
MIRT2447390	hsa-miR-3679-5p	CLIP-seq
MIRT2506124	hsa-miR-383	CLIP-seq
MIRT2506125	hsa-miR-3913-3p	CLIP-seq
MIRT2506126	hsa-miR-3921	CLIP-seq
MIRT2447391	hsa-miR-3972	CLIP-seq
MIRT2447392	hsa-miR-4307	CLIP-seq
MIRT2447393	hsa-miR-4328	CLIP-seq
MIRT901509	hsa-miR-4446-5p	CLIP-seq
MIRT2506127	hsa-miR-4653-5p	CLIP-seq
MIRT2506128	hsa-miR-4659a-3p	CLIP-seq
MIRT2506129	hsa-miR-4659b-3p	CLIP-seq
MIRT2447397	hsa-miR-4708-5p	CLIP-seq
MIRT2506130	hsa-miR-4735-5p	CLIP-seq
MIRT901514	hsa-miR-4755-5p	CLIP-seq
MIRT2506131	hsa-miR-4766-5p	CLIP-seq
MIRT2447399	hsa-miR-4770	CLIP-seq
MIRT2506132	hsa-miR-4772-5p	CLIP-seq
MIRT2447400	hsa-miR-4791	CLIP-seq
MIRT2506133	hsa-miR-489	CLIP-seq
MIRT2506134	hsa-miR-513a-3p	CLIP-seq
MIRT2447401	hsa-miR-520a-5p	CLIP-seq
MIRT2447402	hsa-miR-525-5p	CLIP-seq
MIRT2506135	hsa-miR-548ae	CLIP-seq
MIRT2506136	hsa-miR-548aj	CLIP-seq
MIRT2506137	hsa-miR-548am	CLIP-seq
MIRT2506138	hsa-miR-548x	CLIP-seq
MIRT901517	hsa-miR-619	CLIP-seq
MIRT2447403	hsa-miR-623	CLIP-seq
MIRT2506139	hsa-miR-942	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0007131	Process	Reciprocal meiotic recombination	IBA	21873635
GO:0007283	Process	Spermatogenesis	IEA
GO:0035861	Component	Site of double-strand break	IBA	21873635

Other IDs

• MIM: 618166
• HGNC: 26847
• e!Ensembl: ENSG00000176563

Protein

• UniProt ID: Q8N815
• Protein name: Cyclin N-terminal domain-containing protein 1
• Protein function: Plays a role in the different steps of crossover formation during meiotic recombination. Participates in the crossover differentiation step of crossover-specific recombination intermediates through its interaction with PRR19. In addition, stimul
• Sequence:

  MDGPMRPRSASLVDFQFGVVATETIEDALLHLAQQNEQAVREASGRLGRFREPQIVEFVF
  LLSEQWCLEKSVSYQAVEILERFMVKQAENICRQATIQPRDNKRESQNWRALKQQLVNKF
  TLRLVSCVQLASKLSFRNKIISNITVLNFLQALGYLHTKEELLESELDVLKSLNFRINLP
  TPLAYVETLLEVLGYNGCLVPAMRLHATCLTLLDLVYLLHEPIYESLLRASIENSTPSQL
  QGEKFTSVKEDFMLLAVGIIAASAFIQNHECWSQVVGHLQSITGIALASIAEFSYAILTH
  GVGANTPGRQQSIPPHLAARALKTVASSNT

• Sequence length: 330

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451, rs397507859, rs80359709, rs80359742, rs80359205, rs80357627, rs80357004, rs80357571, rs80357767, rs80357653, rs80358086, rs80357608, rs28897696, rs41293465, rs146650273, rs63751017, rs63750617, rs63750726, rs63750199, rs63749848, rs398122618, rs398122653, rs397509211, rs80357791, rs121912666, rs587778541, rs121908698, rs536907995, rs587781302, rs140342925, rs587781506, rs587782652, rs587782849, rs587783057, rs10520699, rs11852999, rs139770721, rs374950566, rs786202800, rs863224451, rs377153250, rs747727055, rs876658804, rs780001540, rs760815829, rs878854926, rs775248597, rs886040658, rs886040192, rs786203523, rs886040319, rs397508006, rs587782011, rs1060502772, rs1555461727, rs1553333072, rs1114167702, rs1257401983, rs886040950, rs1060502759, rs774684620, rs142947311, rs1555580883, rs748513310, rs376170600, rs863224499, rs1593909229, rs748453607, rs1294578913, rs1574737047, rs1593909960, rs2081922847, rs2082559544, rs2053694038	29059683