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JDP2 (Jun dimerization protein 2)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
122953
Gene nameGene Name - the full gene name approved by the HGNC.
Jun dimerization protein 2
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
JDP2
SynonymsGene synonyms aliases
JUNDM2
ChromosomeChromosome number
14
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
14q24.3
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT657104 hsa-miR-150-5p HITS-CLIP 23824327
MIRT657103 hsa-miR-6778-3p HITS-CLIP 23824327
MIRT657102 hsa-miR-4757-5p HITS-CLIP 23824327
MIRT657101 hsa-miR-6744-3p HITS-CLIP 23824327
MIRT657100 hsa-miR-6878-3p HITS-CLIP 23824327
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IDA 18671972
GO:0000785 Component Chromatin ISA
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA 21873635
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA 21873635
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q8WYK2
Protein name Jun dimerization protein 2
Protein function Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorig
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00170 bZIP_1
70 133
bZIP transcription factor
Coiled-coil
Sequence
MMPGQIPDPSVTTGSLPGLGPLTGLPSSALTVEELKYADIRNLGAMIAPLHFLEVKLGKR
PQPVKSELDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEE
LKQERQQLILMLN
RHRPTCIVRTDSVKTPESEGNPLLEQLEKK
Sequence length 163
Interactions View interactions
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Basal cell neoplasm Basal Cell Neoplasm, Basal Cell Cancer rs587776578, rs587776579, rs2117956624, rs2118419579, rs2118365442, rs2118041703, rs2136689212, rs2118336503, rs1587692888, rs267606984, rs878853849, rs1554695110, rs1064793921, rs1588605348, rs1588568813 31174203
Carcinoma Basal cell carcinoma rs121912654, rs555607708, rs786202962, rs1564055259 31174203
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297, rs11978267, rs4132601 27903959
Unknown
Disease name Disease term dbSNP ID References
Liver carcinoma Liver carcinoma 20214788

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