Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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118 |
Gene nameGene Name - the full gene name approved by the HGNC.
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Adducin 1 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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ADD1 |
SynonymsGene synonyms aliases
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ADDA |
ChromosomeChromosome number
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4 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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4p16.3 |
SummarySummary of gene provided in NCBI Entrez Gene.
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Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, and gamma). Adducin acts as a heterodimer of the related alpha, beta, or gamma subunits. The protein encoded by this gene represents the alpha subunit. Alpha- and beta-add |
SNPsSNP information provided by dbSNP.
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SNP ID |
Visualize variation |
Clinical significance |
Consequence |
rs4961 |
G>A,T |
Risk-factor, drug-response |
Coding sequence variant, missense variant, non coding transcript variant |
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miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
P35611 |
Protein name |
Alpha-adducin (Erythrocyte adducin subunit alpha) |
Protein function |
Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00596 |
Aldolase_II |
147 → 329 |
Class II Aldolase and Adducin N-terminal domain |
Domain |
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Sequence |
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Sequence length |
737 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Huntington disease |
Huntington Disease |
rs768047421 |
22387017 |
Liver carcinoma |
Liver carcinoma |
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19363144 |
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