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DCD (dermcidin)
Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
117159
Gene nameGene Name - the full gene name approved by the HGNC.
Dermcidin
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
DCD
SynonymsGene synonyms aliases
AIDD, DCD-1, DSEP, HCAP, PIF
ChromosomeChromosome number
12
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q13.2
SummarySummary of gene provided in NCBI Entrez Gene.
This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-te
miRNAmiRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
miRTarBase ID miRNA Experiments Reference
MIRT032404 hsa-let-7b-5p Proteomics 18668040
MIRT925859 hsa-miR-513a-3p CLIP-seq
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding HDA 22658674
GO:0005515 Function Protein binding IPI 25416956, 32296183
GO:0005576 Component Extracellular region IBA 21873635
GO:0005576 Component Extracellular region IDA 9736629
GO:0005576 Component Extracellular region TAS
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID P81605
Protein name Dermcidin (EC 3.4.-.-) (Preproteolysin) [Cleaved into: Survival-promoting peptide; DCD-1]
Protein function [DCD-1]: Found in sweat, has an antimicrobial activity during early bacterial colonization (PubMed:11694882, PubMed:23426625). The secreted peptide assembles into homohexameric complexes that can associate with and also insert into pathogen memb
PDB 2KSG , 2NDK , 2YMK , 6SHK
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15291 Dermcidin
19 → 106
Dermcidin, antibiotic peptide
 Domain
Sequence
Sequence length 110
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
 
Reactome
    Antimicrobial peptides
Associated diseases
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Unknown
Disease name Disease term dbSNP ID References
Liver neoplasms Liver neoplasms 20195826
Liver cancer Malignant neoplasm of liver 20195826

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