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VASN (vasorin)

Gene

114990

Vasorin

VASN

SLITL2

16p13.3

Show/Hide all(128)

miRTarBase ID	miRNA	Experiments	Reference
MIRT018355	hsa-miR-335-5p	Microarray	18185580
MIRT019949	hsa-miR-375	Microarray	20215506
MIRT022816	hsa-miR-124-3p	Microarray	18668037
MIRT031814	hsa-miR-16-5p	Proteomics	18668040
MIRT714521	hsa-miR-22-3p	HITS-CLIP	19536157
MIRT714520	hsa-miR-874-5p	HITS-CLIP	19536157
MIRT574106	hsa-miR-4690-5p	PAR-CLIP	20371350
MIRT574105	hsa-miR-2682-5p	PAR-CLIP	20371350
MIRT574104	hsa-miR-34b-5p	PAR-CLIP	20371350
MIRT574103	hsa-miR-449c-5p	PAR-CLIP	20371350
MIRT574101	hsa-miR-4514	PAR-CLIP	20371350
MIRT574102	hsa-miR-4692	PAR-CLIP	20371350
MIRT574100	hsa-miR-4308	PAR-CLIP	20371350
MIRT574099	hsa-miR-4254	PAR-CLIP	20371350
MIRT574098	hsa-miR-766-5p	PAR-CLIP	20371350
MIRT574096	hsa-miR-7154-3p	PAR-CLIP	20371350
MIRT574097	hsa-miR-765	PAR-CLIP	20371350
MIRT574095	hsa-miR-6894-5p	PAR-CLIP	20371350
MIRT574094	hsa-miR-34a-5p	PAR-CLIP	20371350
MIRT574093	hsa-miR-34c-5p	PAR-CLIP	20371350
MIRT574091	hsa-miR-449a	PAR-CLIP	20371350
MIRT574092	hsa-miR-449b-5p	PAR-CLIP	20371350
MIRT574090	hsa-miR-203b-3p	PAR-CLIP	20371350
MIRT714521	hsa-miR-22-3p	HITS-CLIP	19536157
MIRT714520	hsa-miR-874-5p	HITS-CLIP	19536157
MIRT574106	hsa-miR-4690-5p	PAR-CLIP	20371350
MIRT574105	hsa-miR-2682-5p	PAR-CLIP	20371350
MIRT574104	hsa-miR-34b-5p	PAR-CLIP	20371350
MIRT574103	hsa-miR-449c-5p	PAR-CLIP	20371350
MIRT574101	hsa-miR-4514	PAR-CLIP	20371350
MIRT574102	hsa-miR-4692	PAR-CLIP	20371350
MIRT574100	hsa-miR-4308	PAR-CLIP	20371350
MIRT574099	hsa-miR-4254	PAR-CLIP	20371350
MIRT574098	hsa-miR-766-5p	PAR-CLIP	20371350
MIRT574096	hsa-miR-7154-3p	PAR-CLIP	20371350
MIRT574097	hsa-miR-765	PAR-CLIP	20371350
MIRT574095	hsa-miR-6894-5p	PAR-CLIP	20371350
MIRT574094	hsa-miR-34a-5p	PAR-CLIP	20371350
MIRT574093	hsa-miR-34c-5p	PAR-CLIP	20371350
MIRT574091	hsa-miR-449a	PAR-CLIP	20371350
MIRT574092	hsa-miR-449b-5p	PAR-CLIP	20371350
MIRT574090	hsa-miR-203b-3p	PAR-CLIP	20371350
MIRT1482847	hsa-miR-1180	CLIP-seq
MIRT1482848	hsa-miR-122	CLIP-seq
MIRT1482849	hsa-miR-1254	CLIP-seq
MIRT1482850	hsa-miR-1288	CLIP-seq
MIRT1482851	hsa-miR-1343	CLIP-seq
MIRT1482852	hsa-miR-145	CLIP-seq
MIRT1482853	hsa-miR-1915	CLIP-seq
MIRT1482854	hsa-miR-193a-3p	CLIP-seq
MIRT1482855	hsa-miR-193b	CLIP-seq
MIRT1482856	hsa-miR-205	CLIP-seq
MIRT1482857	hsa-miR-214	CLIP-seq
MIRT1482858	hsa-miR-3116	CLIP-seq
MIRT1482859	hsa-miR-3124-3p	CLIP-seq
MIRT1482860	hsa-miR-3180-5p	CLIP-seq
MIRT1482861	hsa-miR-3199	CLIP-seq
MIRT1482862	hsa-miR-361-3p	CLIP-seq
MIRT1482863	hsa-miR-3619-5p	CLIP-seq
MIRT1482864	hsa-miR-4300	CLIP-seq
MIRT1482865	hsa-miR-4326	CLIP-seq
MIRT1482866	hsa-miR-4420	CLIP-seq
MIRT1482867	hsa-miR-4481	CLIP-seq
MIRT1482868	hsa-miR-4497	CLIP-seq
MIRT1482869	hsa-miR-4530	CLIP-seq
MIRT1482870	hsa-miR-4664-3p	CLIP-seq
MIRT1482871	hsa-miR-4745-5p	CLIP-seq
MIRT1482872	hsa-miR-4754	CLIP-seq
MIRT1482873	hsa-miR-4790-5p	CLIP-seq
MIRT1482874	hsa-miR-516a-3p	CLIP-seq
MIRT1482875	hsa-miR-658	CLIP-seq
MIRT1482876	hsa-miR-761	CLIP-seq
MIRT1482877	hsa-miR-920	CLIP-seq
MIRT1555377	hsa-miR-146b-3p	CLIP-seq
MIRT1555378	hsa-miR-339-5p	CLIP-seq
MIRT1555379	hsa-miR-4421	CLIP-seq
MIRT2145359	hsa-miR-1245b-3p	CLIP-seq
MIRT1482852	hsa-miR-145	CLIP-seq
MIRT2145360	hsa-miR-3150b-3p	CLIP-seq
MIRT1482860	hsa-miR-3180-5p	CLIP-seq
MIRT2145361	hsa-miR-342-3p	CLIP-seq
MIRT2145362	hsa-miR-377	CLIP-seq
MIRT1482865	hsa-miR-4326	CLIP-seq
MIRT2145363	hsa-miR-4422	CLIP-seq
MIRT2145364	hsa-miR-4689	CLIP-seq
MIRT2145365	hsa-miR-4784	CLIP-seq
MIRT2145359	hsa-miR-1245b-3p	CLIP-seq
MIRT2145360	hsa-miR-3150b-3p	CLIP-seq
MIRT1482861	hsa-miR-3199	CLIP-seq
MIRT2145361	hsa-miR-342-3p	CLIP-seq
MIRT2365586	hsa-miR-3622a-5p	CLIP-seq
MIRT2145362	hsa-miR-377	CLIP-seq
MIRT1482865	hsa-miR-4326	CLIP-seq
MIRT2365587	hsa-miR-4423-3p	CLIP-seq
MIRT2145364	hsa-miR-4689	CLIP-seq
MIRT2145365	hsa-miR-4784	CLIP-seq
MIRT1482853	hsa-miR-1915	CLIP-seq
MIRT2145362	hsa-miR-377	CLIP-seq
MIRT2659297	hsa-miR-4287	CLIP-seq
MIRT2659298	hsa-miR-4469	CLIP-seq
MIRT2659299	hsa-miR-4685-3p	CLIP-seq
MIRT2659300	hsa-miR-642a	CLIP-seq
MIRT2659301	hsa-miR-767-3p	CLIP-seq
MIRT1482847	hsa-miR-1180	CLIP-seq
MIRT2694914	hsa-miR-146a	CLIP-seq
MIRT2694915	hsa-miR-146b-5p	CLIP-seq
MIRT1482857	hsa-miR-214	CLIP-seq
MIRT1482859	hsa-miR-3124-3p	CLIP-seq
MIRT1482863	hsa-miR-3619-5p	CLIP-seq
MIRT2694916	hsa-miR-3650	CLIP-seq
MIRT2694917	hsa-miR-3688-5p	CLIP-seq
MIRT2145362	hsa-miR-377	CLIP-seq
MIRT2659297	hsa-miR-4287	CLIP-seq
MIRT1482864	hsa-miR-4300	CLIP-seq
MIRT2694918	hsa-miR-4459	CLIP-seq
MIRT2659298	hsa-miR-4469	CLIP-seq
MIRT1482868	hsa-miR-4497	CLIP-seq
MIRT1482870	hsa-miR-4664-3p	CLIP-seq
MIRT2659299	hsa-miR-4685-3p	CLIP-seq
MIRT2694919	hsa-miR-4722-5p	CLIP-seq
MIRT2694920	hsa-miR-4779	CLIP-seq
MIRT2694921	hsa-miR-589	CLIP-seq
MIRT2659300	hsa-miR-642a	CLIP-seq
MIRT2694922	hsa-miR-644	CLIP-seq
MIRT1482876	hsa-miR-761	CLIP-seq
MIRT2659301	hsa-miR-767-3p	CLIP-seq
MIRT2694923	hsa-miR-885-3p	CLIP-seq
MIRT1482877	hsa-miR-920	CLIP-seq

Show/Hide all(20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005615	Component	Extracellular space	IBA	21873635
GO:0005615	Component	Extracellular space	IDA	15247411, 21170088
GO:0005739	Component	Mitochondrion	IEA
GO:0005765	Component	Lysosomal membrane	HDA	17897319
GO:0005886	Component	Plasma membrane	IBA	21873635
GO:0009986	Component	Cell surface	IDA	15247411
GO:0010719	Process	Negative regulation of epithelial to mesenchymal transition	IMP	21170088
GO:0016021	Component	Integral component of membrane	IEA
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IBA	21873635
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IDA	15247411
GO:0030512	Process	Negative regulation of transforming growth factor beta receptor signaling pathway	IMP	21170088
GO:0031012	Component	Extracellular matrix	IBA	21873635
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0050431	Function	Transforming growth factor beta binding	IBA	21873635
GO:0050431	Function	Transforming growth factor beta binding	IPI	15247411
GO:0070062	Component	Extracellular exosome	HDA	19056867, 23533145
GO:0070062	Component	Extracellular exosome	IDA	21082674
GO:0071456	Process	Cellular response to hypoxia	IEA
GO:0071461	Process	Cellular response to redox state	IEA

MIM	HGNC	e!Ensembl
608843	18517	ENSG00000168140

Protein

UniProt ID

Q6EMK4

Protein name

Vasorin (Protein slit-like 2)

Protein function

May act as an inhibitor of TGF-beta signaling.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13855	LRR_8	56 → 112	Leucine rich repeat	Repeat
PF13855	LRR_8	100 → 160	Leucine rich repeat	Repeat
PF13855	LRR_8	192 → 250	Leucine rich repeat	Repeat
PF00008	EGF	409 → 440	EGF-like domain	Domain

Sequence

MCSRVPLLLPLLLLLALGPGVQGCPSGCQCSQPQTVFCTARQGTTVPRDVPPDTVGLYVF
ENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETF
RGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDLSHNS
LLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRG
LTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPF
NCVCPLSWFGPWVRESHVTLASPEETRCHFPPKNAGRLLLELDYADFGCPATTTTATVPT
TRPVVREPTALSSSLAPTWLSPTEPATEAPSPPSTAPPTVGPVPQPQDCPPSTCLNGGTC
HLGTRHHLACLCPEGFTGLYCESQMGQGTRPSPTPVTPRPPRSLTLGIEPVSPTSLRVGL
QRYLQGSSVQLRSLRLTYRNLSGPDKRLVTLRLPASLAEYTVTQLRPNATYSVCVMPLGP
GRVPEGEEACGEAHTPPAVHSNHAPVTQAREGNLPLLIAPALAAVLLAALAAVGAAYCVR
RGRAMAAAAQDKGQVGPGAGPLELEGVKVPLEPGPKATEGGGEALPSGSECEVPLMGFPG
PGLQSPLHAKPYI

Sequence length

673

Interactions

View interactions

Associated diseases

Show/Hide Unknown Diseases (1)

Unknown
Disease name	Disease term	dbSNP ID	References
Liver carcinoma	Liver carcinoma		25826090

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