KLHL32 (kelch like family member 32)

Gene

• Entrez ID: 114792
• Gene name: Kelch like family member 32
• Gene symbol: KLHL32
• Synonyms: BKLHD5, KIAA1900, UG0030H05, dJ21F7.1
• Chromosome: 6
• Chromosome location: 6q16.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT018022	hsa-miR-335-5p	Microarray	18185580
MIRT445939	hsa-miR-3200-5p	PAR-CLIP	22100165
MIRT445938	hsa-miR-4251	PAR-CLIP	22100165
MIRT445937	hsa-miR-4329	PAR-CLIP	22100165
MIRT445936	hsa-miR-6761-5p	PAR-CLIP	22100165
MIRT445935	hsa-miR-4693-3p	PAR-CLIP	22100165
MIRT445934	hsa-miR-1827	PAR-CLIP	22100165
MIRT445932	hsa-miR-6765-5p	PAR-CLIP	22100165
MIRT445933	hsa-miR-1304-5p	PAR-CLIP	22100165
MIRT445941	hsa-miR-3617-5p	PAR-CLIP	22100165
MIRT445940	hsa-miR-641	PAR-CLIP	22100165
MIRT445939	hsa-miR-3200-5p	PAR-CLIP	22100165
MIRT445938	hsa-miR-4251	PAR-CLIP	22100165
MIRT445937	hsa-miR-4329	PAR-CLIP	22100165
MIRT445936	hsa-miR-6761-5p	PAR-CLIP	22100165
MIRT445935	hsa-miR-4693-3p	PAR-CLIP	22100165
MIRT445934	hsa-miR-1827	PAR-CLIP	22100165
MIRT445932	hsa-miR-6765-5p	PAR-CLIP	22100165
MIRT445933	hsa-miR-1304-5p	PAR-CLIP	22100165
MIRT445939	hsa-miR-3200-5p	PAR-CLIP	22100165
MIRT445938	hsa-miR-4251	PAR-CLIP	22100165
MIRT445937	hsa-miR-4329	PAR-CLIP	22100165
MIRT445936	hsa-miR-6761-5p	PAR-CLIP	22100165
MIRT445935	hsa-miR-4693-3p	PAR-CLIP	22100165
MIRT445934	hsa-miR-1827	PAR-CLIP	22100165
MIRT445932	hsa-miR-6765-5p	PAR-CLIP	22100165
MIRT445933	hsa-miR-1304-5p	PAR-CLIP	22100165
MIRT445941	hsa-miR-3617-5p	PAR-CLIP	22100165
MIRT445940	hsa-miR-641	PAR-CLIP	22100165
MIRT445939	hsa-miR-3200-5p	PAR-CLIP	22100165
MIRT445938	hsa-miR-4251	PAR-CLIP	22100165
MIRT445937	hsa-miR-4329	PAR-CLIP	22100165
MIRT445936	hsa-miR-6761-5p	PAR-CLIP	22100165
MIRT445935	hsa-miR-4693-3p	PAR-CLIP	22100165
MIRT445934	hsa-miR-1827	PAR-CLIP	22100165
MIRT445932	hsa-miR-6765-5p	PAR-CLIP	22100165
MIRT445933	hsa-miR-1304-5p	PAR-CLIP	22100165
MIRT1098514	hsa-miR-1206	CLIP-seq
MIRT1098515	hsa-miR-1238	CLIP-seq
MIRT1098516	hsa-miR-1258	CLIP-seq
MIRT1098517	hsa-miR-3148	CLIP-seq
MIRT1098518	hsa-miR-3646	CLIP-seq
MIRT1098519	hsa-miR-4307	CLIP-seq
MIRT1098520	hsa-miR-433	CLIP-seq
MIRT1098521	hsa-miR-4496	CLIP-seq
MIRT1098522	hsa-miR-4670-3p	CLIP-seq
MIRT1098523	hsa-miR-4691-5p	CLIP-seq
MIRT1098524	hsa-miR-5096	CLIP-seq
MIRT1098525	hsa-miR-548ae	CLIP-seq
MIRT1098526	hsa-miR-548aj	CLIP-seq
MIRT1098527	hsa-miR-548am	CLIP-seq
MIRT1098528	hsa-miR-548x	CLIP-seq
MIRT2026779	hsa-miR-4477a	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32814053

Other IDs

• MIM: HGNC
• e!Ensembl: HGNC

Protein

• UniProt ID: Q96NJ5
• Protein name: Kelch-like protein 32 (BTB and kelch domain-containing protein 5)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00651	BTB	32 → 139	BTB/POZ domain	Domain
  PF07707	BACK	144 → 245	BTB And C-terminal Kelch	Domain
  PF01344	Kelch_1	335 → 385	Kelch motif	Repeat
  PF01344	Kelch_1	387 → 432	Kelch motif	Repeat
  PF01344	Kelch_1	483 → 530	Kelch motif	Repeat

• Sequence:

  MPSERCLSIQEMLTGQRLCHSESHNDSVLAALNQQRSDGILCDITLIAEEQKFHAHKAVL
  AACSDYFRAMFSLCMVESGADEVNLHGVTSLGLKQALEFAYTGQILLEPGVIQDVLAAGS
  HLQLLELLNLCSHYLIQELNSFNYLDLYRLADLFNLTLLEKAVIDFLVKHLSELLKSRPE
  EVLTLPYCLLQEVLKSDRLTSLSEEQIWQLAVRWLEHNCHYQYMDELLQYIRFGLMDVDT
  LHTVALSHPLVQASETATALVNEALEYHQSIYAQPVWQTRRTKPRFQSDTLYIIGGKKRE
  VCKVKELRYFNPVDQENALIAAIANWSELAPMPVGRSHHCVAVMGDFLFVAGGEVEHASG
  RTCAVRTACRYDPRSNSWAEIAPMKNCREHFVLGAMEEYLYAVGGRNELRQVLPTVERYC
  PKKNKWTFVQSFDRSLSCHAGYVADGLLWISGGVTNTAQYQNRLMVYEPNQNKWISRSPM
  LQRRVYHSMAAVQRKLYVLGGNDLDYNNDRILVRHIDSYNIDTDQWTRCNFNLLTGQNES
  GVAVHNGRIYLVGGYSIWTNEPLACIQVLDVSREGKEEVFYGPTLPFASNGIAACFLPAP
  YFTCPNLQTLQVPHHRIGTI

• Sequence length: 620

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Chronic obstructive pulmonary disease	Chronic Obstructive Airway Disease	rs2227956, rs1008438, rs1043618, rs562047, rs1061581, rs2763979, rs6457452, rs13147758, rs1828591, rs13118928	26634245