Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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11014 |
Gene nameGene Name - the full gene name approved by the HGNC.
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KDEL endoplasmic reticulum protein retention receptor 2 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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KDELR2 |
SynonymsGene synonyms aliases
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ELP-1, ELP1, ERD2.2, OI21 |
ChromosomeChromosome number
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7 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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7p22.1 |
SummarySummary of gene provided in NCBI Entrez Gene.
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Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-ter |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
P33947 |
Protein name |
ER lumen protein-retaining receptor 2 (ERD2-like protein 1) (ELP-1) (KDEL endoplasmic reticulum protein retention receptor 2) (KDEL receptor 2) |
Protein function |
Membrane receptor that binds the K-D-E-L sequence motif in the C-terminal part of endoplasmic reticulum resident proteins and maintains their localization in that compartment by participating to their vesicle-mediated recycling back from the Gol |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00810 |
ER_lumen_recept |
28 → 169 |
ER lumen protein retaining receptor |
Family |
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Sequence |
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Sequence length |
212 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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