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RAB32 (RAB32, member RAS oncogene family)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
10981
Gene nameGene Name - the full gene name approved by the HGNC.
RAB32, member RAS oncogene family
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
RAB32
SynonymsGene synonyms aliases
PARK26
ChromosomeChromosome number
6
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6q24.3
SummarySummary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene anchors the type II regulatory subunit of protein kinase A to the mitochondrion and aids in mitochondrial fission. The encoded protein also appears to be involved in autophagy and melanosome secretion. Variations in this g
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT022613 hsa-miR-124-3p Microarray 18668037
MIRT029421 hsa-miR-26b-5p Microarray 19088304
MIRT516466 hsa-miR-6512-5p PAR-CLIP 20371350
MIRT516465 hsa-miR-8083 PAR-CLIP 20371350
MIRT516464 hsa-miR-506-5p PAR-CLIP 20371350
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003924 Function GTPase activity IBA 21873635
GO:0003924 Function GTPase activity IDA 21808068
GO:0005515 Function Protein binding IPI 21808068, 22511774, 25360523, 31552791, 32296183
GO:0005525 Function GTP binding NAS 22511774
GO:0005739 Component Mitochondrion IBA 21873635
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q13637
Protein name Ras-related protein Rab-32 (EC 3.6.5.2)
Protein function The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (PubMed:11784320, PubMed:21808068). Rabs cycle between an inactive GDP-bound form and an acti
PDB 4CYM , 4CZ2 , 5OEC , 5OED , 6FF8
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00071 Ras
27 194
Ras family
Domain
Sequence
Sequence length 225
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
Reactome
    RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs
Associated diseases
Causal
Disease name Disease term dbSNP ID References
Dermatitis Dermatitis, Allergic Contact rs61816761, rs150597413, rs138726443, rs201356558, rs149484917, rs372754256, rs747301529, rs567795279, rs745915174 17374397
Leprosy Leprosy rs121917864, rs2239704 22019778

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