ASCC3 (activating signal cointegrator 1 complex subunit 3)

Gene

• Entrez ID: 10973
• Gene name: Activating signal cointegrator 1 complex subunit 3
• Gene symbol: ASCC3
• Synonyms: ASC1p200, HELIC1, MRT81, RNAH
• Chromosome: 6
• Chromosome location: 6q16.3
• Summary: This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT022461	hsa-miR-124-3p	Microarray	18668037
MIRT027593	hsa-miR-98-5p	Microarray	19088304
MIRT028510	hsa-miR-30a-5p	Proteomics	18668040
MIRT031604	hsa-miR-16-5p	Proteomics	18668040
MIRT032308	hsa-let-7b-5p	Proteomics	18668040
MIRT052581	hsa-let-7a-5p	CLASH	23622248
MIRT051396	hsa-let-7f-5p	CLASH	23622248
MIRT039333	hsa-miR-425-5p	CLASH	23622248
MIRT036492	hsa-miR-1226-3p	CLASH	23622248
MIRT802620	hsa-miR-101	CLIP-seq
MIRT802621	hsa-miR-1184	CLIP-seq
MIRT802622	hsa-miR-1193	CLIP-seq
MIRT802623	hsa-miR-1273g	CLIP-seq
MIRT802624	hsa-miR-1297	CLIP-seq
MIRT802625	hsa-miR-1343	CLIP-seq
MIRT802626	hsa-miR-200b	CLIP-seq
MIRT802627	hsa-miR-200c	CLIP-seq
MIRT802628	hsa-miR-2053	CLIP-seq
MIRT802629	hsa-miR-217	CLIP-seq
MIRT802630	hsa-miR-26a	CLIP-seq
MIRT802631	hsa-miR-26b	CLIP-seq
MIRT802632	hsa-miR-3074-5p	CLIP-seq
MIRT802633	hsa-miR-30a	CLIP-seq
MIRT802634	hsa-miR-30b	CLIP-seq
MIRT802635	hsa-miR-30c	CLIP-seq
MIRT802636	hsa-miR-30d	CLIP-seq
MIRT802637	hsa-miR-30e	CLIP-seq
MIRT802638	hsa-miR-3690	CLIP-seq
MIRT802639	hsa-miR-3922-5p	CLIP-seq
MIRT802640	hsa-miR-4252	CLIP-seq
MIRT802641	hsa-miR-4254	CLIP-seq
MIRT802642	hsa-miR-4289	CLIP-seq
MIRT802643	hsa-miR-429	CLIP-seq
MIRT802644	hsa-miR-4318	CLIP-seq
MIRT802645	hsa-miR-4418	CLIP-seq
MIRT802646	hsa-miR-4465	CLIP-seq
MIRT802647	hsa-miR-4470	CLIP-seq
MIRT802648	hsa-miR-4495	CLIP-seq
MIRT802649	hsa-miR-4691-3p	CLIP-seq
MIRT802650	hsa-miR-4716-5p	CLIP-seq
MIRT802651	hsa-miR-4717-5p	CLIP-seq
MIRT802652	hsa-miR-4719	CLIP-seq
MIRT802653	hsa-miR-4753-5p	CLIP-seq
MIRT802654	hsa-miR-4777-5p	CLIP-seq
MIRT802655	hsa-miR-4799-5p	CLIP-seq
MIRT802656	hsa-miR-498	CLIP-seq
MIRT802657	hsa-miR-509-3-5p	CLIP-seq
MIRT802658	hsa-miR-509-5p	CLIP-seq
MIRT802659	hsa-miR-563	CLIP-seq
MIRT802660	hsa-miR-1251	CLIP-seq
MIRT802661	hsa-miR-15a	CLIP-seq
MIRT802662	hsa-miR-15b	CLIP-seq
MIRT802663	hsa-miR-16	CLIP-seq
MIRT802664	hsa-miR-195	CLIP-seq
MIRT802633	hsa-miR-30a	CLIP-seq
MIRT802634	hsa-miR-30b	CLIP-seq
MIRT802635	hsa-miR-30c	CLIP-seq
MIRT802636	hsa-miR-30d	CLIP-seq
MIRT802637	hsa-miR-30e	CLIP-seq
MIRT802665	hsa-miR-3667-3p	CLIP-seq
MIRT802666	hsa-miR-3671	CLIP-seq
MIRT802667	hsa-miR-371b-5p	CLIP-seq
MIRT802668	hsa-miR-3942-3p	CLIP-seq
MIRT802669	hsa-miR-411	CLIP-seq
MIRT802670	hsa-miR-424	CLIP-seq
MIRT802671	hsa-miR-4524	CLIP-seq
MIRT802649	hsa-miR-4691-3p	CLIP-seq
MIRT802672	hsa-miR-497	CLIP-seq
MIRT802673	hsa-miR-503	CLIP-seq
MIRT802674	hsa-miR-618	CLIP-seq
MIRT802675	hsa-miR-633	CLIP-seq
MIRT802676	hsa-miR-646	CLIP-seq
MIRT802677	hsa-miR-936	CLIP-seq
MIRT802622	hsa-miR-1193	CLIP-seq
MIRT802625	hsa-miR-1343	CLIP-seq
MIRT802632	hsa-miR-3074-5p	CLIP-seq
MIRT802638	hsa-miR-3690	CLIP-seq
MIRT802641	hsa-miR-4254	CLIP-seq
MIRT802656	hsa-miR-498	CLIP-seq
MIRT802659	hsa-miR-563	CLIP-seq
MIRT802620	hsa-miR-101	CLIP-seq
MIRT1937009	hsa-miR-329	CLIP-seq
MIRT1937010	hsa-miR-362-3p	CLIP-seq
MIRT1937011	hsa-miR-371-5p	CLIP-seq
MIRT1937012	hsa-miR-3941	CLIP-seq
MIRT1937013	hsa-miR-433	CLIP-seq
MIRT1937014	hsa-miR-4645-3p	CLIP-seq
MIRT1937015	hsa-miR-4789-3p	CLIP-seq
MIRT1937016	hsa-miR-514	CLIP-seq
MIRT1937017	hsa-miR-514b-3p	CLIP-seq
MIRT1937018	hsa-miR-603	CLIP-seq
MIRT1937019	hsa-miR-642b	CLIP-seq
MIRT802620	hsa-miR-101	CLIP-seq
MIRT802621	hsa-miR-1184	CLIP-seq
MIRT802622	hsa-miR-1193	CLIP-seq
MIRT2176781	hsa-miR-1273f	CLIP-seq
MIRT802623	hsa-miR-1273g	CLIP-seq
MIRT2176782	hsa-miR-127-5p	CLIP-seq
MIRT2176783	hsa-miR-1289	CLIP-seq
MIRT802624	hsa-miR-1297	CLIP-seq
MIRT802625	hsa-miR-1343	CLIP-seq
MIRT2176784	hsa-miR-143	CLIP-seq
MIRT802626	hsa-miR-200b	CLIP-seq
MIRT802627	hsa-miR-200c	CLIP-seq
MIRT802629	hsa-miR-217	CLIP-seq
MIRT802630	hsa-miR-26a	CLIP-seq
MIRT802631	hsa-miR-26b	CLIP-seq
MIRT802632	hsa-miR-3074-5p	CLIP-seq
MIRT802633	hsa-miR-30a	CLIP-seq
MIRT802634	hsa-miR-30b	CLIP-seq
MIRT802635	hsa-miR-30c	CLIP-seq
MIRT802636	hsa-miR-30d	CLIP-seq
MIRT802637	hsa-miR-30e	CLIP-seq
MIRT2176785	hsa-miR-3177-5p	CLIP-seq
MIRT2176786	hsa-miR-3198	CLIP-seq
MIRT2176787	hsa-miR-3607-5p	CLIP-seq
MIRT2176788	hsa-miR-3682-5p	CLIP-seq
MIRT802638	hsa-miR-3690	CLIP-seq
MIRT802639	hsa-miR-3922-5p	CLIP-seq
MIRT802640	hsa-miR-4252	CLIP-seq
MIRT802641	hsa-miR-4254	CLIP-seq
MIRT2176789	hsa-miR-4282	CLIP-seq
MIRT802642	hsa-miR-4289	CLIP-seq
MIRT802643	hsa-miR-429	CLIP-seq
MIRT2176790	hsa-miR-4294	CLIP-seq
MIRT2176791	hsa-miR-4309	CLIP-seq
MIRT802644	hsa-miR-4318	CLIP-seq
MIRT802645	hsa-miR-4418	CLIP-seq
MIRT802646	hsa-miR-4465	CLIP-seq
MIRT802647	hsa-miR-4470	CLIP-seq
MIRT802648	hsa-miR-4495	CLIP-seq
MIRT2176792	hsa-miR-4635	CLIP-seq
MIRT2176793	hsa-miR-4666-5p	CLIP-seq
MIRT802649	hsa-miR-4691-3p	CLIP-seq
MIRT2176794	hsa-miR-4708-5p	CLIP-seq
MIRT802650	hsa-miR-4716-5p	CLIP-seq
MIRT2176795	hsa-miR-4733-5p	CLIP-seq
MIRT2176796	hsa-miR-4770	CLIP-seq
MIRT2176797	hsa-miR-491-3p	CLIP-seq
MIRT802656	hsa-miR-498	CLIP-seq
MIRT802657	hsa-miR-509-3-5p	CLIP-seq
MIRT802658	hsa-miR-509-5p	CLIP-seq
MIRT2176798	hsa-miR-526b	CLIP-seq
MIRT802659	hsa-miR-563	CLIP-seq
MIRT2176799	hsa-miR-600	CLIP-seq
MIRT2176800	hsa-miR-668	CLIP-seq
MIRT802622	hsa-miR-1193	CLIP-seq
MIRT802625	hsa-miR-1343	CLIP-seq
MIRT802632	hsa-miR-3074-5p	CLIP-seq
MIRT802638	hsa-miR-3690	CLIP-seq
MIRT802641	hsa-miR-4254	CLIP-seq
MIRT802659	hsa-miR-563	CLIP-seq
MIRT802622	hsa-miR-1193	CLIP-seq
MIRT802624	hsa-miR-1297	CLIP-seq
MIRT802625	hsa-miR-1343	CLIP-seq
MIRT802630	hsa-miR-26a	CLIP-seq
MIRT802631	hsa-miR-26b	CLIP-seq
MIRT802632	hsa-miR-3074-5p	CLIP-seq
MIRT802638	hsa-miR-3690	CLIP-seq
MIRT802639	hsa-miR-3922-5p	CLIP-seq
MIRT802641	hsa-miR-4254	CLIP-seq
MIRT802646	hsa-miR-4465	CLIP-seq
MIRT802647	hsa-miR-4470	CLIP-seq
MIRT802656	hsa-miR-498	CLIP-seq
MIRT802659	hsa-miR-563	CLIP-seq
MIRT802640	hsa-miR-4252	CLIP-seq
MIRT2444086	hsa-miR-297	CLIP-seq
MIRT2176793	hsa-miR-4666-5p	CLIP-seq
MIRT2444087	hsa-miR-567	CLIP-seq
MIRT802620	hsa-miR-101	CLIP-seq
MIRT802622	hsa-miR-1193	CLIP-seq
MIRT2176781	hsa-miR-1273f	CLIP-seq
MIRT802623	hsa-miR-1273g	CLIP-seq
MIRT802625	hsa-miR-1343	CLIP-seq
MIRT2480150	hsa-miR-141	CLIP-seq
MIRT2176784	hsa-miR-143	CLIP-seq
MIRT2480151	hsa-miR-200a	CLIP-seq
MIRT802632	hsa-miR-3074-5p	CLIP-seq
MIRT802633	hsa-miR-30a	CLIP-seq
MIRT802634	hsa-miR-30b	CLIP-seq
MIRT802635	hsa-miR-30c	CLIP-seq
MIRT802636	hsa-miR-30d	CLIP-seq
MIRT802637	hsa-miR-30e	CLIP-seq
MIRT2480152	hsa-miR-3156-5p	CLIP-seq
MIRT2480153	hsa-miR-3618	CLIP-seq
MIRT802638	hsa-miR-3690	CLIP-seq
MIRT802639	hsa-miR-3922-5p	CLIP-seq
MIRT802640	hsa-miR-4252	CLIP-seq
MIRT802641	hsa-miR-4254	CLIP-seq
MIRT2480154	hsa-miR-4263	CLIP-seq
MIRT2176789	hsa-miR-4282	CLIP-seq
MIRT802642	hsa-miR-4289	CLIP-seq
MIRT802647	hsa-miR-4470	CLIP-seq
MIRT802648	hsa-miR-4495	CLIP-seq
MIRT2176794	hsa-miR-4708-5p	CLIP-seq
MIRT802650	hsa-miR-4716-5p	CLIP-seq
MIRT2176796	hsa-miR-4770	CLIP-seq
MIRT802656	hsa-miR-498	CLIP-seq
MIRT802659	hsa-miR-563	CLIP-seq
MIRT2480155	hsa-miR-576-5p	CLIP-seq
MIRT2480156	hsa-miR-934	CLIP-seq
MIRT802620	hsa-miR-101	CLIP-seq
MIRT802622	hsa-miR-1193	CLIP-seq
MIRT2176781	hsa-miR-1273f	CLIP-seq
MIRT802623	hsa-miR-1273g	CLIP-seq
MIRT802624	hsa-miR-1297	CLIP-seq
MIRT802625	hsa-miR-1343	CLIP-seq
MIRT2480150	hsa-miR-141	CLIP-seq
MIRT2176784	hsa-miR-143	CLIP-seq
MIRT2480151	hsa-miR-200a	CLIP-seq
MIRT802630	hsa-miR-26a	CLIP-seq
MIRT802631	hsa-miR-26b	CLIP-seq
MIRT802632	hsa-miR-3074-5p	CLIP-seq
MIRT802633	hsa-miR-30a	CLIP-seq
MIRT802634	hsa-miR-30b	CLIP-seq
MIRT802635	hsa-miR-30c	CLIP-seq
MIRT802636	hsa-miR-30d	CLIP-seq
MIRT802637	hsa-miR-30e	CLIP-seq
MIRT2480152	hsa-miR-3156-5p	CLIP-seq
MIRT2480153	hsa-miR-3618	CLIP-seq
MIRT802638	hsa-miR-3690	CLIP-seq
MIRT802639	hsa-miR-3922-5p	CLIP-seq
MIRT802640	hsa-miR-4252	CLIP-seq
MIRT802641	hsa-miR-4254	CLIP-seq
MIRT2480154	hsa-miR-4263	CLIP-seq
MIRT2176789	hsa-miR-4282	CLIP-seq
MIRT802642	hsa-miR-4289	CLIP-seq
MIRT802646	hsa-miR-4465	CLIP-seq
MIRT802647	hsa-miR-4470	CLIP-seq
MIRT802648	hsa-miR-4495	CLIP-seq
MIRT2176794	hsa-miR-4708-5p	CLIP-seq
MIRT802650	hsa-miR-4716-5p	CLIP-seq
MIRT802652	hsa-miR-4719	CLIP-seq
MIRT2675494	hsa-miR-4731-3p	CLIP-seq
MIRT2176795	hsa-miR-4733-5p	CLIP-seq
MIRT2176796	hsa-miR-4770	CLIP-seq
MIRT2675495	hsa-miR-4789-5p	CLIP-seq
MIRT2675496	hsa-miR-4801	CLIP-seq
MIRT802656	hsa-miR-498	CLIP-seq
MIRT802659	hsa-miR-563	CLIP-seq
MIRT2480155	hsa-miR-576-5p	CLIP-seq
MIRT2480156	hsa-miR-934	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22681889
GO:0003723	Function	RNA binding	IBA	21873635
GO:0005515	Function	Protein binding	IPI	22055184
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	IDA	12077347
GO:0005634	Component	Nucleus	TAS	22055184
GO:0005654	Component	Nucleoplasm	TAS
GO:0005829	Component	Cytosol	IDA
GO:0006307	Process	DNA dealkylation involved in DNA repair	IDA	22055184
GO:0006307	Process	DNA dealkylation involved in DNA repair	TAS
GO:0008283	Process	Cell population proliferation	IMP	22055184
GO:0016020	Component	Membrane	HDA	19946888
GO:0016607	Component	Nuclear speck	IEA
GO:0032508	Process	DNA duplex unwinding	IDA	22055184
GO:0043138	Function	3'-5' DNA helicase activity	IBA	21873635
GO:0043138	Function	3'-5' DNA helicase activity	IDA	22055184
GO:0099053	Component	Activating signal cointegrator 1 complex	IDA	12077347

Other IDs

• MIM: 614217
• HGNC: 18697
• e!Ensembl: ENSG00000112249

Protein

• UniProt ID: Q8N3C0
• Protein name: Activating signal cointegrator 1 complex subunit 3 (EC 5.6.2.4) (ASC-1 complex subunit p200) (ASC1p200) (Helicase, ATP binding 1) (Trip4 complex subunit p200)
• Protein function: ATPase involved both in DNA repair and rescue of stalled ribosomes (PubMed:22055184, PubMed:28757607, PubMed:32099016, PubMed:32579943, PubMed:36302773). 3'-5' DNA helicase involved in repair of alkylated DNA: promotes DNA unwinding to generate
• PDB: 6YXQ, 8ALZ
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00270	DEAD	478 → 657	DEAD/DEAH box helicase	Domain
  PF00271	Helicase_C	699 → 857	Helicase conserved C-terminal domain	Family
  PF02889	Sec63	978 → 1286	Sec63 Brl domain	Family
  PF00270	DEAD	1328 → 1500	DEAD/DEAH box helicase	Domain
  PF00271	Helicase_C	1545 → 1694	Helicase conserved C-terminal domain	Family
  PF02889	Sec63	1812 → 2176	Sec63 Brl domain	Family

• Sequence:

  MALPRLTGALRSFSNVTKQDNYNEEVADLKIKRSKLHEQVLDLGLTWKKIIKFLNEKLEK
  SKMQSINEDLKDILHAAKQIVGTDNGREAIESGAAFLFMTFHLKDSVGHKETKAIKQMFG
  PFPSSSATAACNATNRIISHFSQDDLTALVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFD
  ELPINGETQKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTE
  VPRVEDLCCTLYDMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSSND
  HRFQALQDNCKKILGENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAGEDLEV
  SEGLMCFDPKELRIQREQALLNARSVPILSRQRDADVEKIHYPHVYDSQAEAMKTSAFIA
  GAKMILPEGIQRENNKLYEEVRIPYSEPMPLSFEEKPVYIQDLDEIGQLAFKGMKRLNRI
  QSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMK
  ALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVA
  LSQIVRLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATF
  LHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMV
  FVHARNATVRTAMSLIERAKNCGHIPFFFPTQGHDYVLAEKQVQRSRNKQVRELFPDGFS
  IHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVD
  LGILDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNA
  EIALGTVTNVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRK
  LDKAQMIRFEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEE
  FDQIKVREEEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSA
  YVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTR
  LEEKKLTVDKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTL
  SIYADFTWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIF
  EPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEA
  LYNFSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAP
  LKALVRERMDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQN
  RNYVQQVTILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLA
  DWLNIKQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLI
  FVSSRRQTRLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHH
  AGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPI
  TDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIA
  GGTITSKQDALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYC
  IEIGEDNRSIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPV
  RHNEDHMNSELAKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQA
  LRVCQAMLDVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKP
  IMKGPHARGRTSIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGI
  SVKGSWDDLVEGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPES
  CAVTPRFPKSKDEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLY
  FMSDCYLGLDQQYDIYLNVTQASLSAQVNTKVSDSLTDLALK

• Sequence length: 2202

Pathways

Reactome:

ALKBH3 mediated reversal of alkylation damage

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Mental retardation	Profound Mental Retardation, Mental deficiency, Intellectual Disability	rs5742905, rs267607136, rs267607137, rs2131714307, rs267607038, rs267607042, rs80338685, rs137853127, rs80338815, rs28940893, rs387906309, rs121908096, rs121908099, rs587784365, rs121918315, rs121918316, rs397515320, rs121434489, rs1585215916, rs267607233, rs267606752, rs137852214, rs606231193, rs132630297, rs80338758, rs137852815, rs122455132, rs28935171, rs122453113, rs122445108, rs28934904, rs28934908, rs28935468, rs61748421, rs121918624, rs202060209, rs80338708, rs113994198, rs199422192, rs387906635, rs1554770064, rs1057519611, rs1060499526, rs387906636, rs1057519612, rs281875189, rs281875322, rs387906799, rs387906804, rs875989800, rs797045262, rs387906845, rs387906846, rs876657378, rs281875227, rs281875228, rs281875229, rs281875230, rs387906861, rs370667926, rs387906932, rs387906943, rs1557612719, rs387907190, rs387907191, rs2126499522, rs587776908, rs1560982564, rs80359505, rs398123009, rs587776929, rs587776930, rs397514555, rs398122824, rs398122825, rs397514556, rs2147483647, rs587776937, rs397514627, rs397514655, rs397514656, rs730882192, rs1587520018, rs1581995953, rs1554121970, rs1581987445, rs397514670, rs376395543, rs137854128, rs397509411, rs397509412, rs397514741, rs398122394, rs879255516, rs397518483, rs398122406, rs398122412, rs398123561, rs200667343, rs587777162, rs587777202, rs62507350, rs587777219, rs587777225, rs587777226, rs587779750, rs587777326, rs587777334, rs281875332, rs587780470, rs587780474, rs587780486, rs587777378, rs587777406, rs587777408, rs587777409, rs587777411, rs587777522, rs527236034, rs527236035, rs267608571, rs267608382, rs267608597, rs61753979, rs61751444, rs267608493, rs587777644, rs587777645, rs587777646, rs587777703, rs587779388, rs606231266, rs606231267, rs672601340, rs606231268, rs672601341, rs606231269, rs672601342, rs606231270, rs606231271, rs606231272, rs606231273, rs587784566, rs587784092, rs587783749, rs587783747, rs587783640, rs587783483, rs606231456, rs606231457, rs606231458, rs606231459, rs672601370, rs672601369, rs672601371, rs672601367, rs672601366, rs672601365, rs672601364, rs672601363, rs672601362, rs672601376, rs672601377, rs672601378, rs724159949, rs724159950, rs724159948, rs724159956, rs724159953, rs727502860, rs727502861, rs730882197, rs749995448, rs786205143, rs794726770, rs1135401808, rs786205583, rs786205595, rs786205859, rs794727792, rs794727928, rs794729221, rs797044519, rs797044523, rs797044521, rs797044524, rs797044526, rs797044522, rs797044520, rs794727642, rs796052719, rs781746113, rs796052510, rs796052733, rs796052724, rs796052728, rs796052676, rs796053353, rs796053366, rs796053368, rs1555103986, rs1555110818, rs796052571, rs1555110843, rs796052626, rs796052618, rs796053290, rs796052217, rs672601368, rs797045164, rs797044961, rs797044962, rs200070245, rs797044963, rs869320675, rs869320676, rs797045012, rs752746786, rs797044885, rs797044925, rs797044854, rs797044849, rs797044930, rs797044901, rs797044918, rs797044884, rs797045177, rs797045178, rs797045050, rs797045036, rs797045053, rs797045047, rs797045037, rs797045042, rs797045041, rs879255261, rs782397980, rs797045263, rs797045264, rs797045655, rs797045586, rs545185248, rs797046031, rs797046028, rs797046029, rs797046030, rs797045249, rs797045529, rs797045952, rs797045984, rs797045540, rs797045539, rs797045989, rs863224930, rs869025202, rs863225264, rs863225077, rs876661308, rs869025222, rs864309560, rs758252808, rs745756308, rs869025286, rs869025287, rs869025578, rs143038880, rs869025579, rs869025580, rs869025581, rs869312704, rs869312674, rs869312677, rs869312689, rs869312693, rs869312698, rs869312708, rs869312711, rs869312826, rs869312825, rs869312824, rs869312823, rs758432471, rs869312821, rs761993070, rs869312844, rs869312842, rs869312843, rs869312841, rs869312847, rs869320632, rs869312955, rs773432002, rs869320713, rs869320772, rs869320773, rs879255270, rs875989848, rs875989849, rs1716457622, rs2108414289, rs878854401, rs875989786, rs1085307109, rs1085307108, rs876657679, rs876661167, rs876661076, rs876661055, rs876661219, rs876661064, rs876661151, rs876661041, rs200440467, rs876661295, rs878853045, rs878853143, rs878853142, rs878853149, rs1555910048, rs878853152, rs878853146, rs878853145, rs878853141, rs878853151, rs878853144, rs878853148, rs878853147, rs878853251, rs878853269, rs879253762, rs886037841, rs879253888, rs879253931, rs879254016, rs879255618, rs879255619, rs879255620, rs886037847, rs879255621, rs886039332, rs746177928, rs886039520, rs886041003, rs886041058, rs750035706, rs886041059, rs886041060, rs886041061, rs886041090, rs886041088, rs886041089, rs886041095, rs886041097, rs886041989, rs886041944, rs886041692, rs886041593, rs886041687, rs886041207, rs886041309, rs886041239, rs886041448, rs138336847, rs149644940, rs886041295, rs886041521, rs886041125, rs886042041, rs886041238, rs886041469, rs886041197, rs886041291, rs886041658, rs886041705, rs886041876, rs139716296, rs1057516030, rs1057517408, rs749655461, rs141179774, rs370916968, rs1057517676, rs1057517933, rs1057517708, rs1057518352, rs1057518183, rs1057518474, rs1057518204, rs1057517825, rs1057518796, rs1057518961, rs1057518772, rs1057518988, rs1057519004, rs1057518700, rs772450541, rs371310428, rs1057519019, rs1057519491, rs1057519546, rs1057519560, rs1057519565, rs1057519400, rs1057519402, rs1057519405, rs1057519593, rs1057519594, rs1057519628, rs1556912828, rs1060505029, rs1060505030, rs147001633, rs1057519947, rs1057519617, rs1057524832, rs774592932, rs797045045, rs1039571136, rs1555910821, rs1060499626, rs1060499655, rs1554770185, rs1060499936, rs1060501153, rs1060501151, rs1064792984, rs1060503378, rs1060503386, rs1060503383, rs1060500046, rs1064792999, rs1060505033, rs1064796564, rs1064797002, rs1064793161, rs150802299, rs1064796830, rs1064794996, rs1064795444, rs1064796034, rs1064796403, rs1064794979, rs1064796765, rs1064793539, rs760933323, rs1064793546, rs1064796406, rs1064796367, rs780441716, rs1064794894, rs1064796023, rs1064797355, rs1085307484, rs1064794935, rs1085307547, rs1131690804, rs757511770, rs1131691875, rs1131691979, rs398122823, rs1131691866, rs1131692159, rs1131692228, rs1131692154, rs113331868, rs1554121872, rs1554121875, rs926027867, rs1554122123, rs1554122129, rs1287121256, rs1554122526, rs1554123982, rs1554385102, rs1554385111, rs1554385305, rs1554386687, rs1554389088, rs1554402092, rs1554434435, rs1135401778, rs1135401760, rs1135401770, rs1135401771, rs1135401768, rs1135401779, rs1135401805, rs1135401797, rs1135401799, rs1135401816, rs1135401823, rs1135401824, rs1555769968, rs1135401825, rs1135401955, rs1135401956, rs1135401957, rs1135401958, rs1554129040, rs1554150543, rs1553188463, rs1553146165, rs1485978447, rs1361547443, rs750079325, rs369692236, rs1554231836, rs749188610, rs1554122735, rs1554689877, rs1174482090, rs781053477, rs1554623112, rs1555409836, rs1555411305, rs770014321, rs1555984461, rs1555990958, rs762292772, rs1554944271, rs1057524157, rs1485749468, rs1555984343, rs1293450628, rs373584239, rs1553722309, rs1553738686, rs1376334317, rs1553722294, rs1553283831, rs1554120589, rs1555985554, rs1555877287, rs1555411378, rs750922282, rs1553264873, rs1554263326, rs1554264268, rs1554263626, rs1554263625, rs766614772, rs1553620494, rs1555050158, rs1555050165, rs1555050171, rs1555050174, rs765556214, rs1402086660, rs1554645052, rs1555661648, rs1293246328, rs749494995, rs775592405, rs1553265189, rs1553242856, rs1553247374, rs1553241570, rs1553997065, rs1553998565, rs1380822792, rs1555028154, rs1555023232, rs1553194155, rs1553130904, rs1553152590, rs1553567864, rs1553638614, rs120074160, rs1554486894, rs1554767754, rs1554843977, rs1555443581, rs1555443600, rs1555439545, rs1555525088, rs770680174, rs1555889130, rs373178770, rs1555985532, rs1553519853, rs781325598, rs1410587479, rs1553638086, rs150259543, rs1554093891, rs1554121228, rs1554120498, rs1554121189, rs1212517874, rs1554770628, rs1555979158, rs1554770054, rs771610568, rs1451230055, rs1554770624, rs1555906707, rs1555906768, rs1555906781, rs1555907620, rs1555907623, rs1555907626, rs1555907653, rs1555907864, rs1554094145, rs1554202698, rs1554200722, rs773327091, rs1555607621, rs1555604778, rs1555607159, rs1555607682, rs1553364018, rs1553324416, rs1555411394, rs1554102556, rs1554122363, rs1555705966, rs1555103971, rs1555408401, rs1554461593, rs1554304254, rs1554120978, rs1047509819, rs1555982601, rs767774867, rs1554789246, rs1555111511, rs1555950676, rs1555954380, rs1555985649, rs1553194162, rs1553518509, rs1274633498, rs1554274371, rs1554122252, rs1554122458, rs1554122729, rs1554297905, rs1554776342, rs1554770046, rs1554770667, rs1554792556, rs1452715535, rs1555444885, rs1555534147, rs1427624649, rs1555611722, rs1555744282, rs1555706391, rs1178702025, rs1555984102, rs1554770589, rs1554121443, rs1559791842, rs1559824939, rs1555889127, rs1236702036, rs1553510280, rs1553511175, rs1553511226, rs1554150552, rs1554275163, rs1554201137, rs1553517991, rs1553518511, rs1553517984, rs1553518752, rs1554119814, rs1554122293, rs1554122341, rs1554122689, rs1554770243, rs1554770444, rs1557045250, rs959316981, rs1556270312, rs1553270640, rs978179634, rs1554093884, rs1491240980, rs1555943484, rs1554121453, rs1334099693, rs1554048616, rs1555660806, rs1555644480, rs1555651572, rs1567844992, rs1567855081, rs1567855669, rs1567855704, rs1567856045, rs1567856331, rs1567860075, rs1567860112, rs1567860640, rs1567860891, rs754919272, rs1567860919, rs1567861468, rs1567861489, rs1567861501, rs1567861894, rs1567863732, rs1567864750, rs1567877108, rs1567878511, rs758785463, rs1553808301, rs1553245038, rs1553789166, rs1553813646, rs1553631860, rs1554121265, rs1554770262, rs1555034768, rs1555984433, rs779009256, rs1553994814, rs1553996086, rs1553996072, rs1553270599, rs1553153291, rs760262127, rs1554119274, rs1554121878, rs1554387293, rs1554385203, rs757077698, rs750612085, rs1554776500, rs1564360978, rs1554776933, rs1554776938, rs1565278132, rs1567368243, rs1558478047, rs375695605, rs1558479778, rs1558501648, rs1565240833, rs114727354, rs1557591264, rs1557620758, rs1559099927, rs1561788984, rs369459721, rs1563831738, rs1562159088, rs1562159562, rs1562159599, rs1559094754, rs1559328283, rs755634856, rs1561784687, rs1554122296, rs1561789313, rs1562720119, rs1564363665, rs1561697465, rs1561785003, rs1561787845, rs1561789215, rs1554122305, rs1561784553, rs1561784560, rs1561787690, rs1554122888, rs749632782, rs1567139896, rs1569370887, rs1569371303, rs1564493599, rs1561875779, rs1569146542, rs1569146649, rs1275489527, rs1560115921, rs1468772495, rs749969789, rs1560108090, rs1569376809, rs1569355102, rs1560103306, rs1564365418, rs1559855453, rs1562928193, rs1558149913, rs1253072668, rs141976414, rs1558371790, rs1557898800, rs1567758622, rs1567844041, rs1567844114, rs1567920106, rs1567920209, rs138247472, rs1567974030, rs1567995650, rs1283838287, rs1568003569, rs1568006217, rs1568018905, rs1562505675, rs1561783309, rs1555980234, rs1559087186, rs1560966086, rs1560330387, rs769471341, rs1562493608, rs1562505335, rs1554121861, rs1554122200, rs1562957809, rs1568097623, rs1391600900, rs1568234874, rs1568235086, rs1555990955, rs1567870541, rs1557570794, rs1562869207, rs1571818248, rs1431778557, rs369691608, rs1595808957, rs1597665063, rs1597846084, rs1603401125, rs1603350606, rs1601946481, rs1601932069, rs1602880906, rs1602308324, rs1574554519, rs1573882268, rs1603198937, rs1558148010, rs1558498928, rs1569459580, rs1569380375, rs1560062082, rs1557889974, rs1558414255, rs756429763, rs781663444, rs1569016820, rs1569017025, rs1569017160, rs1557612048, rs1568504941, rs1581987022, rs1576983339, rs1599892470, rs1265340906, rs1602284689, rs1574949440, rs1576220938, rs1576280892, rs1576288424, rs1574459612, rs1574511051, rs1575654528, rs1577094794, rs1294683568, rs771819481, rs1580984895, rs1581338441, rs1580988138, rs1581980317, rs1581986872, rs1554121207, rs1581987268, rs1581987476, rs1581987885, rs763770519, rs1581991929, rs1581992099, rs1581992998, rs1581995453, rs1554122242, rs1581996778, rs1581997228, rs1588735247, rs1555980467, rs1555985742, rs1601319086, rs1601970168, rs1574451881, rs876661168, rs1576994053, rs1573589807, rs1581036396, rs1601267617, rs1572531830, rs1573483715, rs1590954686, rs1601315812, rs1573965358, rs1573972562, rs529087882, rs1570609440, rs1598940393, rs1575333081, rs1576028676, rs1596476657, rs1599375711, rs1603290366, rs1603060007, rs1603069440, rs1592939069, rs1591612223, rs2062994512, rs373701249, rs1600471396, rs1600501018, rs1600504088, rs1600514073, rs748436953, rs765723607, rs758170522, rs1561785045, rs1357591960, rs1591609136, rs1596891223, rs1579370234, rs2047850664, rs1579109565, rs1870202051, rs1574887674, rs778229060, rs1572531281, rs1570622663, rs1573501865, rs1576086299, rs1576164991, rs1574907198, rs1576656734, rs1554121438, rs1581995425, rs1581996813, rs1582001015, rs1588324025, rs1591371152, rs1590008294, rs1590956245, rs1590028691, rs1591606580, rs1591611001, rs1591612317, rs1591612370, rs763436882, rs997044541, rs1595897117, rs747706524, rs1579377990, rs1201878175, rs1894051550, rs1572531730, rs1579576029, rs1577017863, rs752545577, rs1582461267, rs1589460606, rs1588727276, rs1598620094, rs1599368323, rs1600082188, rs1601319352, rs1598226304, rs2076013475, rs2076017638, rs1600596180, rs1554121932, rs1680676671, rs1570607996, rs1382444181, rs1570640673, rs1574994308, rs1596667777, rs1602226289, rs1595629181, rs1595609005, rs1227643933, rs1572705473, rs1570621899, rs1722830922, rs1575094649, rs1417035592, rs1581997098, rs1589457762, rs1598211790, rs758726258, rs1601071971, rs863224922, rs1586692481, rs1586692548, rs1586692551, rs1580988074, rs1594129609, rs1588732344, rs1579368865, rs1586660389, rs1586660370, rs1586660338, rs1586657848, rs1586660381, rs1791701214, rs752676391, rs1680673822, rs758098717, rs1726676630, rs762288077, rs1759964009, rs1760905766, rs1761021165, rs1554121934, rs2055849544, rs1049773, rs587784300, rs1861628072, rs1761241410, rs1064797322, rs1948652423, rs2059194330, rs1777174302, rs2054280202, rs2081190512, rs772665884, rs1400164869, rs1861593395, rs1760897843, rs1761087122, rs1388355040, rs2068797192, rs1777175608, rs376898131	21937992