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TMED2 (transmembrane p24 trafficking protein 2)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
10959
Gene nameGene Name - the full gene name approved by the HGNC.
Transmembrane p24 trafficking protein 2
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
TMED2
SynonymsGene synonyms aliases
P24A, RNP24, p24, p24b1, p24beta1
ChromosomeChromosome number
12
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q24.31
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT005187 hsa-miR-30a-5p pSILAC 18668040
MIRT016541 hsa-miR-193b-3p Proteomics 21512034
MIRT005187 hsa-miR-30a-5p Proteomics;Other 18668040
MIRT047764 hsa-miR-7-5p CLASH 23622248
MIRT039998 hsa-miR-615-3p CLASH 23622248
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane TAS
GO:0001843 Process Neural tube closure IEA
GO:0001893 Process Maternal placenta development IEA
GO:0001947 Process Heart looping IEA
GO:0005515 Function Protein binding IPI 10359607, 12237308, 17693410, 18287528, 20361938, 20427317, 21219331
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q15363
Protein name Transmembrane emp24 domain-containing protein 2 (Membrane protein p24A) (p24) (p24 family protein beta-1) (p24beta1)
Protein function Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesic
PDB 5AZW
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01105 EMP24_GP25L
20 196
emp24/gp25L/p24 family/GOLD
Domain
Sequence
Sequence length 201
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
 
Reactome
    Pre-NOTCH Processing in Golgi
COPII-mediated vesicle transport
Cargo concentration in the ER
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
Associated diseases
Unknown
Disease name Disease term dbSNP ID References
Myocardial ischemia Myocardial Ischemia 16214533

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