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SERINC3 (serine incorporator 3)
Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
10955
Gene nameGene Name - the full gene name approved by the HGNC.
Serine incorporator 3
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
SERINC3
SynonymsGene synonyms aliases
AIGP1, DIFF33, SBBI99, TDE, TDE1, TMS-1
ChromosomeChromosome number
20
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
20q13.12
miRNAmiRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
miRTarBase ID miRNA Experiments Reference
MIRT005842 hsa-miR-204-5p Luciferase reporter assay, Microarray, qRT-PCR 21282569
MIRT020296 hsa-miR-130b-3p Sequencing 20371350
MIRT024221 hsa-miR-218-5p Sequencing 20371350
MIRT031259 hsa-miR-19b-3p Sequencing 20371350
MIRT039739 hsa-miR-615-3p CLASH 23622248
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0005515 Function Protein binding IPI 32814053
GO:0005886 Component Plasma membrane TAS
GO:0006564 Process L-serine biosynthetic process TAS
GO:0006658 Process Phosphatidylserine metabolic process IEA
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q13530
Protein name Serine incorporator 3 (Tumor differentially expressed protein 1)
Protein function Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm (PubMed:26416733, PubMed:26416734). Non-ATP
PDB 7RU6 , 7RUG
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03348 Serinc
16 → 471
Serine incorporator (Serinc)
 Family
Sequence
Sequence length 473
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
 
KEGG
  
Reactome
  Viral life cycle - HIV-1   Serine biosynthesis
Associated diseases
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Causal
Disease name Disease term dbSNP ID References
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 17013881
Unknown
Disease name Disease term dbSNP ID References
Prostatic neoplasms Prostatic Neoplasms 17013881

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