Gene
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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10945 |
Gene nameGene Name - the full gene name approved by the HGNC.
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KDEL endoplasmic reticulum protein retention receptor 1 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
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KDELR1 |
SynonymsGene synonyms aliases
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ERD2, ERD2.1, HDEL, PM23 |
ChromosomeChromosome number
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19 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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19q13.33 |
SummarySummary of gene provided in NCBI Entrez Gene.
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Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-ter |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
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UniProt ID |
P24390 |
Protein name |
ER lumen protein-retaining receptor 1 (KDEL endoplasmic reticulum protein retention receptor 1) (KDEL receptor 1) (Putative MAPK-activating protein PM23) |
Protein function |
Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum. {ECO:0000269|PubMed:11703931, ECO:0000269|PubMed:14 |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00810 |
ER_lumen_recept |
28 → 169 |
ER lumen protein retaining receptor |
Family |
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Sequence |
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Sequence length |
212 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
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Causal |
Disease name |
Disease term |
dbSNP ID |
References |
Prostate cancer |
Malignant neoplasm of prostate |
rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 |
17013881 |
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Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Prostatic neoplasms |
Prostatic Neoplasms |
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17013881 |
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