MTMR11 (myotubularin related protein 11)

Gene

• Entrez ID: 10903
• Gene name: Myotubularin related protein 11
• Gene symbol: MTMR11
• Synonyms: CRA
• Chromosome: 1
• Chromosome location: 1q21.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1163698	hsa-miR-320a	CLIP-seq
MIRT1163699	hsa-miR-320b	CLIP-seq
MIRT1163700	hsa-miR-320c	CLIP-seq
MIRT1163701	hsa-miR-320d	CLIP-seq
MIRT1163702	hsa-miR-3616-5p	CLIP-seq
MIRT1163703	hsa-miR-3647-5p	CLIP-seq
MIRT1163704	hsa-miR-4429	CLIP-seq
MIRT1163705	hsa-miR-4446-3p	CLIP-seq
MIRT1163706	hsa-miR-4656	CLIP-seq
MIRT1163707	hsa-miR-4795-5p	CLIP-seq
MIRT1163708	hsa-miR-573	CLIP-seq
MIRT1163709	hsa-miR-595	CLIP-seq
MIRT2047062	hsa-miR-105	CLIP-seq
MIRT2047063	hsa-miR-205	CLIP-seq
MIRT2047064	hsa-miR-3671	CLIP-seq
MIRT2047065	hsa-miR-607	CLIP-seq
MIRT2575021	hsa-miR-1248	CLIP-seq
MIRT2575022	hsa-miR-2467-5p	CLIP-seq
MIRT2575023	hsa-miR-3188	CLIP-seq
MIRT1163698	hsa-miR-320a	CLIP-seq
MIRT1163699	hsa-miR-320b	CLIP-seq
MIRT1163700	hsa-miR-320c	CLIP-seq
MIRT1163701	hsa-miR-320d	CLIP-seq
MIRT2575024	hsa-miR-3606	CLIP-seq
MIRT1163702	hsa-miR-3616-5p	CLIP-seq
MIRT1163703	hsa-miR-3647-5p	CLIP-seq
MIRT2575025	hsa-miR-3674	CLIP-seq
MIRT2575026	hsa-miR-3975	CLIP-seq
MIRT1163704	hsa-miR-4429	CLIP-seq
MIRT1163705	hsa-miR-4446-3p	CLIP-seq
MIRT2575027	hsa-miR-4649-3p	CLIP-seq
MIRT1163706	hsa-miR-4656	CLIP-seq
MIRT1163707	hsa-miR-4795-5p	CLIP-seq
MIRT2575028	hsa-miR-485-5p	CLIP-seq
MIRT2575029	hsa-miR-548p	CLIP-seq
MIRT1163708	hsa-miR-573	CLIP-seq
MIRT1163709	hsa-miR-595	CLIP-seq
MIRT2575030	hsa-miR-921	CLIP-seq
MIRT2575021	hsa-miR-1248	CLIP-seq
MIRT2685488	hsa-miR-2276	CLIP-seq
MIRT2575022	hsa-miR-2467-5p	CLIP-seq
MIRT2575023	hsa-miR-3188	CLIP-seq
MIRT1163698	hsa-miR-320a	CLIP-seq
MIRT1163699	hsa-miR-320b	CLIP-seq
MIRT1163700	hsa-miR-320c	CLIP-seq
MIRT1163701	hsa-miR-320d	CLIP-seq
MIRT2575024	hsa-miR-3606	CLIP-seq
MIRT1163702	hsa-miR-3616-5p	CLIP-seq
MIRT1163703	hsa-miR-3647-5p	CLIP-seq
MIRT2575025	hsa-miR-3674	CLIP-seq
MIRT2575026	hsa-miR-3975	CLIP-seq
MIRT1163704	hsa-miR-4429	CLIP-seq
MIRT1163705	hsa-miR-4446-3p	CLIP-seq
MIRT2685489	hsa-miR-451b	CLIP-seq
MIRT2575027	hsa-miR-4649-3p	CLIP-seq
MIRT1163706	hsa-miR-4656	CLIP-seq
MIRT2685490	hsa-miR-4696	CLIP-seq
MIRT1163707	hsa-miR-4795-5p	CLIP-seq
MIRT2575028	hsa-miR-485-5p	CLIP-seq
MIRT2575029	hsa-miR-548p	CLIP-seq
MIRT1163708	hsa-miR-573	CLIP-seq
MIRT1163709	hsa-miR-595	CLIP-seq
MIRT2575030	hsa-miR-921	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004438	Function	Phosphatidylinositol-3-phosphatase activity	IBA	21873635
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0005737	Component	Cytoplasm	IDA	16787938
GO:0016020	Component	Membrane	IBA	21873635
GO:0046856	Process	Phosphatidylinositol dephosphorylation	IBA	21873635
GO:0070062	Component	Extracellular exosome	HDA	18570454

Other IDs

• MIM: HGNC
• e!Ensembl: HGNC

Protein

• UniProt ID: A4FU01
• Protein name: Myotubularin-related protein 11 (Cisplatin resistance-associated protein) (hCRA) (Inactive phosphatidylinositol 3-phosphatase 11)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF06602	Myotub-related	169 → 318	Myotubularin-like phosphatase domain	Domain
  PF06602	Myotub-related	302 → 483	Myotubularin-like phosphatase domain	Domain
  PF12578	3-PAP	548 → 678	Myotubularin-associated protein	Family

• Sequence:

  MWWGGRGQSFNIAPQKEEPEMGSVQENRMPEPRSRQPSSCLASRCLPGEQILAWAPGVRK
  GLEPELSGTLICTNFRVTFQPCGWQWNQDTPLNSEYDFALVNIGRLEAVSGLSRVQLLRP
  GSLHKFIPEEILIHGRDFRLLRVGFEAGGLEPQAFQVTMAIVQARAQSNQAQQYSGITLS
  KAGQGSGSRKPPIPLMETAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRIL
  DSEVRRAFGHFHQGRGPRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVELMLQAGHSDV
  VLVDTMDELPSLADVQLAHLRLRALCLPDSSVAEDKWLSALEGTRWLDYVRACLRKASDI
  SVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLT
  RLGGTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPW
  ERGKQSGQLNSYTQVYTPGYSQPPAGNSFNLQLSVWDWDLRYSNAQILQFQNPGYDPEHC
  PDSWLPRPQPSFMVPGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRPAISSE
  SLADQEWGLPSHWGACPLPPGLLLPGYLGPQIRLWRRCYLRGRPEVQMGLSAPTISGLQD
  ELSHLQELLRKWTPRISPEDHSKKRDPHTILNPTEIAGILKGRAEGDLG

• Sequence length: 709

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451, rs397507859, rs80359709, rs80359742, rs80359205, rs80357627, rs80357004, rs80357571, rs80357767, rs80357653, rs80358086, rs80357608, rs28897696, rs41293465, rs146650273, rs63751017, rs63750617, rs63750726, rs63750199, rs63749848, rs398122618, rs398122653, rs397509211, rs80357791, rs121912666, rs587778541, rs121908698, rs536907995, rs587781302, rs140342925, rs587781506, rs587782652, rs587782849, rs587783057, rs10520699, rs11852999, rs139770721, rs374950566, rs786202800, rs863224451, rs377153250, rs747727055, rs876658804, rs780001540, rs760815829, rs878854926, rs775248597, rs886040658, rs886040192, rs786203523, rs886040319, rs397508006, rs587782011, rs1060502772, rs1555461727, rs1553333072, rs1114167702, rs1257401983, rs886040950, rs1060502759, rs774684620, rs142947311, rs1555580883, rs748513310, rs376170600, rs863224499, rs1593909229, rs748453607, rs1294578913, rs1574737047, rs1593909960, rs2081922847, rs2082559544, rs2053694038	29059683