STARD10 (StAR related lipid transfer domain containing 10)

Gene

• Entrez ID: 10809
• Gene name: StAR related lipid transfer domain containing 10
• Gene symbol: STARD10
• Synonyms: CGI-52, NY-CO-28, PCTP2, SDCCAG28
• Chromosome: 11
• Chromosome location: 11q13.4

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT003632	hsa-miR-661	immunoblot, qRT-PCR	20543867
MIRT731281	hsa-miR-638	Immunoblot, Luciferase reporter assay, qRT-PCR	28412359
MIRT731281	hsa-miR-638	Immunoblot, Luciferase reporter assay, qRT-PCR	28412359
MIRT731281	hsa-miR-638	Immunoblot, Luciferase reporter assay, qRT-PCR	28412359
MIRT731281	hsa-miR-638	Immunoblot, Luciferase reporter assay, qRT-PCR	28412359
MIRT1395133	hsa-miR-103a	CLIP-seq
MIRT1395134	hsa-miR-107	CLIP-seq
MIRT1395135	hsa-miR-1184	CLIP-seq
MIRT1395136	hsa-miR-1227	CLIP-seq
MIRT1395137	hsa-miR-1275	CLIP-seq
MIRT1395138	hsa-miR-1538	CLIP-seq
MIRT1395139	hsa-miR-198	CLIP-seq
MIRT1395140	hsa-miR-3065-3p	CLIP-seq
MIRT1395141	hsa-miR-3175	CLIP-seq
MIRT1395142	hsa-miR-4260	CLIP-seq
MIRT1395143	hsa-miR-4283	CLIP-seq
MIRT1395144	hsa-miR-4447	CLIP-seq
MIRT1395145	hsa-miR-4472	CLIP-seq
MIRT1395146	hsa-miR-4489	CLIP-seq
MIRT1395147	hsa-miR-4525	CLIP-seq
MIRT1395148	hsa-miR-4665-5p	CLIP-seq
MIRT1395149	hsa-miR-4715-3p	CLIP-seq
MIRT1395150	hsa-miR-4723-5p	CLIP-seq
MIRT1395151	hsa-miR-4728-5p	CLIP-seq
MIRT1395152	hsa-miR-4733-3p	CLIP-seq
MIRT1395153	hsa-miR-4745-3p	CLIP-seq
MIRT1395154	hsa-miR-4755-3p	CLIP-seq
MIRT1395155	hsa-miR-4783-3p	CLIP-seq
MIRT1395156	hsa-miR-625	CLIP-seq
MIRT1395157	hsa-miR-760	CLIP-seq
MIRT1395158	hsa-miR-764	CLIP-seq
MIRT1395139	hsa-miR-198	CLIP-seq
MIRT1395142	hsa-miR-4260	CLIP-seq
MIRT1395143	hsa-miR-4283	CLIP-seq
MIRT1395146	hsa-miR-4489	CLIP-seq
MIRT1395154	hsa-miR-4755-3p	CLIP-seq
MIRT1395157	hsa-miR-760	CLIP-seq
MIRT2340614	hsa-miR-106a	CLIP-seq
MIRT2340615	hsa-miR-106b	CLIP-seq
MIRT1395137	hsa-miR-1275	CLIP-seq
MIRT2340616	hsa-miR-1286	CLIP-seq
MIRT2340617	hsa-miR-17	CLIP-seq
MIRT2340618	hsa-miR-20a	CLIP-seq
MIRT2340619	hsa-miR-20b	CLIP-seq
MIRT1395141	hsa-miR-3175	CLIP-seq
MIRT1395144	hsa-miR-4447	CLIP-seq
MIRT1395145	hsa-miR-4472	CLIP-seq
MIRT1395147	hsa-miR-4525	CLIP-seq
MIRT1395148	hsa-miR-4665-5p	CLIP-seq
MIRT1395149	hsa-miR-4715-3p	CLIP-seq
MIRT2340620	hsa-miR-4722-5p	CLIP-seq
MIRT1395150	hsa-miR-4723-5p	CLIP-seq
MIRT1395151	hsa-miR-4728-5p	CLIP-seq
MIRT1395152	hsa-miR-4733-3p	CLIP-seq
MIRT2340621	hsa-miR-519a	CLIP-seq
MIRT2340622	hsa-miR-519b-3p	CLIP-seq
MIRT2340623	hsa-miR-519c-3p	CLIP-seq
MIRT2340624	hsa-miR-519d	CLIP-seq
MIRT1395156	hsa-miR-625	CLIP-seq
MIRT1395158	hsa-miR-764	CLIP-seq
MIRT2340625	hsa-miR-93	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	23455924
GO:0005829	Component	Cytosol	IBA	21873635
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005902	Component	Microvillus	IBA	21873635
GO:0006656	Process	Phosphatidylcholine biosynthetic process	TAS
GO:0006869	Process	Lipid transport	IEA
GO:0008289	Function	Lipid binding	IEA
GO:0016020	Component	Membrane	IBA	21873635
GO:0031514	Component	Motile cilium	IEA
GO:0046581	Component	Intercellular canaliculus	IBA	21873635

Other IDs

• MIM: 617382
• HGNC: 10666
• e!Ensembl: ENSG00000214530

Protein

• UniProt ID: Q9Y365
• Protein name: START domain-containing protein 10 (StARD10) (Antigen NY-CO-28) (PCTP-like protein) (PCTP-L) (Serologically defined colon cancer antigen 28) (StAR-related lipid transfer protein 10)
• Protein function: May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1
• PDB: 6SER
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01852	START	28 → 226	START domain	Domain

• Sequence:

  MEKLAASTEPQGPRPVLGRESVQVPDDQDFRSFRSECEAEVGWNLTYSRAGVSVWVQAVE
  MDRTLHKIKCRMECCDVPAETLYDVLHDIEYRKKWDSNVIETFDIARLTVNADVGYYSWR
  CPKPLKNRDVITLRSWLPMGADYIIMNYSVKHPKYPPRKDLVRAVSIQTGYLIQSTGPKS
  CVITYLAQVDPKGSLPKWVVNKSSQFLAPKAMKKMYKACLKYPEWKQKHLPHFKPWLHPE
  QSPLPSLALSELSVQHADSLENIDESAVAESREERMGGAGGEGSDDDTSLT

• Sequence length: 291

Pathways

Reactome:

Synthesis of PC

Associated diseases

Causal
Disease name	Disease term	dbSNP ID	References
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	17013881

Unknown
Disease name	Disease term	dbSNP ID	References
Prostatic neoplasms	Prostatic Neoplasms		17013881