Gene
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
10723 |
Gene nameGene Name - the full gene name approved by the HGNC.
|
Solute carrier family 12 member 7 |
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
|
SLC12A7 |
SynonymsGene synonyms aliases
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KCC4 |
ChromosomeChromosome number
|
5 |
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
5p15.33 |
miRNAmiRNA information provided by mirtarbase database.
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Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein
|
UniProt ID |
Q9Y666 |
Protein name |
Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4) |
Protein function |
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling (PubMed:10913127). May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of |
PDB |
7D99
|
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF00324 |
AA_permease |
123 → 320 |
Amino acid permease |
Family |
PF00324 |
AA_permease |
411 → 696 |
Amino acid permease |
Family |
PF03522 |
SLC12 |
708 → 834 |
Solute carrier family 12 |
Family |
PF03522 |
SLC12 |
817 → 1083 |
Solute carrier family 12 |
Family |
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Sequence |
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Sequence length |
1083 |
Interactions |
View interactions |
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
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Associated diseases
|
Unknown |
Disease name |
Disease term |
dbSNP ID |
References |
Urinary bladder cancer |
Malignant neoplasm of urinary bladder |
|
26039340 |
Bladder neoplasm |
Bladder Neoplasm |
|
26039340 |
|