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CGREF1 (cell growth regulator with EF-hand domain 1)

Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
10669
Gene nameGene Name - the full gene name approved by the HGNC.
Cell growth regulator with EF-hand domain 1
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
CGREF1
SynonymsGene synonyms aliases
CGR11
ChromosomeChromosome number
2
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2p23.3
miRNAmiRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT888375 hsa-miR-3120-3p CLIP-seq
MIRT888376 hsa-miR-3912 CLIP-seq
MIRT888377 hsa-miR-448 CLIP-seq
MIRT888378 hsa-miR-105 CLIP-seq
MIRT888379 hsa-miR-22 CLIP-seq
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005509 Function Calcium ion binding IEA
GO:0005576 Component Extracellular region IEA
GO:0007050 Process Cell cycle arrest IEA
GO:0007155 Process Cell adhesion IEA
GO:0008285 Process Negative regulation of cell population proliferation TAS 8968090
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM
HGNC
e!Ensembl
Protein
UniProt ID Q99674
Protein name Cell growth regulator with EF hand domain protein 1 (Cell growth regulatory gene 11 protein) (Hydrophobestin)
Protein function Mediates cell-cell adhesion in a calcium-dependent manner (By similarity). Able to inhibit growth in several cell lines.
Family and domains
Sequence
MLPLTMTVLILLLLPTGQAAPKDGVTRPDSEVQHQLLPNPFQPGQEQLGLLQSYLKGLGR
TEVQLEHLSREQVLLYLFALHDYDQSGQLDGLELLSMLTAALAPGAANSPTTNPVILIVD
KVLETQDLNGDGLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQE
TQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRG
EAGGQAEAEGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLESK
NTQNDFEVHIVQVENDEI
Sequence length 318
Interactions View interactions
Associated diseases
Unknown
Disease name Disease term dbSNP ID References
Liver neoplasms Liver neoplasms 28108177
Liver cancer Malignant neoplasm of liver 28108177

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