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RBM7 (RNA binding motif protein 7)

Gene

10179

RNA binding motif protein 7

RBM7

11q23.2

Show/Hide all(239)

miRTarBase ID	miRNA	Experiments	Reference
MIRT045565	hsa-miR-149-5p	CLASH	23622248
MIRT546799	hsa-miR-3908	PAR-CLIP	21572407
MIRT546798	hsa-miR-875-5p	PAR-CLIP	21572407
MIRT546797	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT546796	hsa-miR-5009-3p	PAR-CLIP	21572407
MIRT546795	hsa-miR-4670-3p	PAR-CLIP	21572407
MIRT546794	hsa-miR-3653-3p	PAR-CLIP	21572407
MIRT546793	hsa-miR-6792-5p	PAR-CLIP	21572407
MIRT546792	hsa-miR-3144-3p	PAR-CLIP	21572407
MIRT546791	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT546790	hsa-miR-4503	PAR-CLIP	21572407
MIRT444177	hsa-miR-490-3p	PAR-CLIP	22100165
MIRT444175	hsa-miR-619-3p	PAR-CLIP	22100165
MIRT444174	hsa-miR-4307	PAR-CLIP	22100165
MIRT444173	hsa-miR-4714-3p	PAR-CLIP	22100165
MIRT444172	hsa-miR-4764-5p	PAR-CLIP	22100165
MIRT444171	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT444170	hsa-miR-578	PAR-CLIP	22100165
MIRT546799	hsa-miR-3908	PAR-CLIP	21572407
MIRT546798	hsa-miR-875-5p	PAR-CLIP	21572407
MIRT546797	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT546796	hsa-miR-5009-3p	PAR-CLIP	21572407
MIRT546795	hsa-miR-4670-3p	PAR-CLIP	21572407
MIRT546794	hsa-miR-3653-3p	PAR-CLIP	21572407
MIRT546793	hsa-miR-6792-5p	PAR-CLIP	21572407
MIRT546792	hsa-miR-3144-3p	PAR-CLIP	21572407
MIRT546791	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT546790	hsa-miR-4503	PAR-CLIP	21572407
MIRT444177	hsa-miR-490-3p	PAR-CLIP	22100165
MIRT444175	hsa-miR-619-3p	PAR-CLIP	22100165
MIRT444174	hsa-miR-4307	PAR-CLIP	22100165
MIRT444173	hsa-miR-4714-3p	PAR-CLIP	22100165
MIRT444172	hsa-miR-4764-5p	PAR-CLIP	22100165
MIRT444171	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT444170	hsa-miR-578	PAR-CLIP	22100165
MIRT1296545	hsa-miR-1285	CLIP-seq
MIRT1296546	hsa-miR-136	CLIP-seq
MIRT1296547	hsa-miR-3187-5p	CLIP-seq
MIRT1296548	hsa-miR-378g	CLIP-seq
MIRT1296549	hsa-miR-412	CLIP-seq
MIRT1296550	hsa-miR-4486	CLIP-seq
MIRT1296551	hsa-miR-4666-5p	CLIP-seq
MIRT1296552	hsa-miR-4672	CLIP-seq
MIRT1296553	hsa-miR-4686	CLIP-seq
MIRT1296554	hsa-miR-4711-3p	CLIP-seq
MIRT1296555	hsa-miR-485-3p	CLIP-seq
MIRT1296556	hsa-miR-487a	CLIP-seq
MIRT1296557	hsa-miR-511	CLIP-seq
MIRT1296558	hsa-miR-607	CLIP-seq
MIRT1296559	hsa-miR-612	CLIP-seq
MIRT1296560	hsa-miR-622	CLIP-seq
MIRT1296561	hsa-miR-885-5p	CLIP-seq
MIRT2088149	hsa-miR-3121-3p	CLIP-seq
MIRT2088150	hsa-miR-3160-5p	CLIP-seq
MIRT2088151	hsa-miR-3671	CLIP-seq
MIRT2088152	hsa-miR-371-5p	CLIP-seq
MIRT2088153	hsa-miR-371b-5p	CLIP-seq
MIRT2313049	hsa-miR-15a	CLIP-seq
MIRT2313050	hsa-miR-15b	CLIP-seq
MIRT2313051	hsa-miR-16	CLIP-seq
MIRT2313052	hsa-miR-195	CLIP-seq
MIRT2313053	hsa-miR-424	CLIP-seq
MIRT2313054	hsa-miR-433	CLIP-seq
MIRT2313055	hsa-miR-4484	CLIP-seq
MIRT2313056	hsa-miR-497	CLIP-seq
MIRT2313057	hsa-miR-548aa	CLIP-seq
MIRT2313058	hsa-miR-548an	CLIP-seq
MIRT1296549	hsa-miR-412	CLIP-seq
MIRT2393555	hsa-miR-4640-3p	CLIP-seq
MIRT2393556	hsa-miR-4667-3p	CLIP-seq
MIRT1296553	hsa-miR-4686	CLIP-seq
MIRT1296555	hsa-miR-485-3p	CLIP-seq
MIRT1296556	hsa-miR-487a	CLIP-seq
MIRT2432471	hsa-miR-3194-3p	CLIP-seq
MIRT2432472	hsa-miR-320a	CLIP-seq
MIRT2432473	hsa-miR-320b	CLIP-seq
MIRT2432474	hsa-miR-320c	CLIP-seq
MIRT2432475	hsa-miR-320d	CLIP-seq
MIRT2432476	hsa-miR-4429	CLIP-seq
MIRT2432477	hsa-miR-549	CLIP-seq
MIRT2609274	hsa-miR-105	CLIP-seq
MIRT2609275	hsa-miR-106a	CLIP-seq
MIRT2609276	hsa-miR-106b	CLIP-seq
MIRT2609277	hsa-miR-1200	CLIP-seq
MIRT2609278	hsa-miR-1305	CLIP-seq
MIRT2609279	hsa-miR-141	CLIP-seq
MIRT2609280	hsa-miR-144	CLIP-seq
MIRT2313049	hsa-miR-15a	CLIP-seq
MIRT2313050	hsa-miR-15b	CLIP-seq
MIRT2313051	hsa-miR-16	CLIP-seq
MIRT2609281	hsa-miR-17	CLIP-seq
MIRT2313052	hsa-miR-195	CLIP-seq
MIRT2609282	hsa-miR-200a	CLIP-seq
MIRT2609283	hsa-miR-20a	CLIP-seq
MIRT2609284	hsa-miR-20b	CLIP-seq
MIRT2609285	hsa-miR-2116	CLIP-seq
MIRT2609286	hsa-miR-297	CLIP-seq
MIRT2609287	hsa-miR-3065-5p	CLIP-seq
MIRT2609288	hsa-miR-3140-5p	CLIP-seq
MIRT2609289	hsa-miR-3143	CLIP-seq
MIRT2609290	hsa-miR-3145-3p	CLIP-seq
MIRT2609291	hsa-miR-3146	CLIP-seq
MIRT2088150	hsa-miR-3160-5p	CLIP-seq
MIRT2609292	hsa-miR-3163	CLIP-seq
MIRT2432471	hsa-miR-3194-3p	CLIP-seq
MIRT2432472	hsa-miR-320a	CLIP-seq
MIRT2432473	hsa-miR-320b	CLIP-seq
MIRT2432474	hsa-miR-320c	CLIP-seq
MIRT2432475	hsa-miR-320d	CLIP-seq
MIRT2609293	hsa-miR-335	CLIP-seq
MIRT2609294	hsa-miR-3609	CLIP-seq
MIRT2609295	hsa-miR-3613-3p	CLIP-seq
MIRT2609296	hsa-miR-375	CLIP-seq
MIRT1296549	hsa-miR-412	CLIP-seq
MIRT2609297	hsa-miR-421	CLIP-seq
MIRT2313053	hsa-miR-424	CLIP-seq
MIRT2609298	hsa-miR-4263	CLIP-seq
MIRT2609299	hsa-miR-4273	CLIP-seq
MIRT2609300	hsa-miR-4328	CLIP-seq
MIRT2313054	hsa-miR-433	CLIP-seq
MIRT2432476	hsa-miR-4429	CLIP-seq
MIRT2609301	hsa-miR-4450	CLIP-seq
MIRT2313055	hsa-miR-4484	CLIP-seq
MIRT2609302	hsa-miR-4495	CLIP-seq
MIRT2609303	hsa-miR-4512	CLIP-seq
MIRT2609304	hsa-miR-451b	CLIP-seq
MIRT2393555	hsa-miR-4640-3p	CLIP-seq
MIRT2609305	hsa-miR-4643	CLIP-seq
MIRT2609306	hsa-miR-466	CLIP-seq
MIRT2393556	hsa-miR-4667-3p	CLIP-seq
MIRT2609307	hsa-miR-4677-5p	CLIP-seq
MIRT1296553	hsa-miR-4686	CLIP-seq
MIRT2609308	hsa-miR-4725-5p	CLIP-seq
MIRT2609309	hsa-miR-4732-5p	CLIP-seq
MIRT2609310	hsa-miR-4742-3p	CLIP-seq
MIRT2609311	hsa-miR-4777-3p	CLIP-seq
MIRT2609312	hsa-miR-4789-3p	CLIP-seq
MIRT2609313	hsa-miR-4796-3p	CLIP-seq
MIRT2609314	hsa-miR-4799-5p	CLIP-seq
MIRT1296555	hsa-miR-485-3p	CLIP-seq
MIRT1296556	hsa-miR-487a	CLIP-seq
MIRT2609315	hsa-miR-491-3p	CLIP-seq
MIRT2609316	hsa-miR-494	CLIP-seq
MIRT2609317	hsa-miR-495	CLIP-seq
MIRT2313056	hsa-miR-497	CLIP-seq
MIRT2609318	hsa-miR-501-3p	CLIP-seq
MIRT2609319	hsa-miR-502-3p	CLIP-seq
MIRT2609320	hsa-miR-504	CLIP-seq
MIRT2609321	hsa-miR-505	CLIP-seq
MIRT2609322	hsa-miR-513a-3p	CLIP-seq
MIRT2609323	hsa-miR-519d	CLIP-seq
MIRT2609324	hsa-miR-526b	CLIP-seq
MIRT2609325	hsa-miR-548ac	CLIP-seq
MIRT2609326	hsa-miR-548ae	CLIP-seq
MIRT2609327	hsa-miR-548ah	CLIP-seq
MIRT2609328	hsa-miR-548aj	CLIP-seq
MIRT2609329	hsa-miR-548am	CLIP-seq
MIRT2313058	hsa-miR-548an	CLIP-seq
MIRT2609330	hsa-miR-548c-3p	CLIP-seq
MIRT2609331	hsa-miR-548d-3p	CLIP-seq
MIRT2609332	hsa-miR-548l	CLIP-seq
MIRT2609333	hsa-miR-548n	CLIP-seq
MIRT2609334	hsa-miR-548x	CLIP-seq
MIRT2609335	hsa-miR-548z	CLIP-seq
MIRT2432477	hsa-miR-549	CLIP-seq
MIRT2609336	hsa-miR-567	CLIP-seq
MIRT2609337	hsa-miR-576-5p	CLIP-seq
MIRT2609338	hsa-miR-582-5p	CLIP-seq
MIRT2609339	hsa-miR-587	CLIP-seq
MIRT2609340	hsa-miR-590-3p	CLIP-seq
MIRT2609341	hsa-miR-619	CLIP-seq
MIRT2609342	hsa-miR-93	CLIP-seq
MIRT2609274	hsa-miR-105	CLIP-seq
MIRT2609277	hsa-miR-1200	CLIP-seq
MIRT2609278	hsa-miR-1305	CLIP-seq
MIRT2609279	hsa-miR-141	CLIP-seq
MIRT2609280	hsa-miR-144	CLIP-seq
MIRT2313049	hsa-miR-15a	CLIP-seq
MIRT2313050	hsa-miR-15b	CLIP-seq
MIRT2313051	hsa-miR-16	CLIP-seq
MIRT2313052	hsa-miR-195	CLIP-seq
MIRT2609282	hsa-miR-200a	CLIP-seq
MIRT2609285	hsa-miR-2116	CLIP-seq
MIRT2609286	hsa-miR-297	CLIP-seq
MIRT2609287	hsa-miR-3065-5p	CLIP-seq
MIRT2609288	hsa-miR-3140-5p	CLIP-seq
MIRT2609291	hsa-miR-3146	CLIP-seq
MIRT2088150	hsa-miR-3160-5p	CLIP-seq
MIRT2432471	hsa-miR-3194-3p	CLIP-seq
MIRT2432472	hsa-miR-320a	CLIP-seq
MIRT2432473	hsa-miR-320b	CLIP-seq
MIRT2432474	hsa-miR-320c	CLIP-seq
MIRT2432475	hsa-miR-320d	CLIP-seq
MIRT2609293	hsa-miR-335	CLIP-seq
MIRT2609295	hsa-miR-3613-3p	CLIP-seq
MIRT2609296	hsa-miR-375	CLIP-seq
MIRT2689469	hsa-miR-410	CLIP-seq
MIRT1296549	hsa-miR-412	CLIP-seq
MIRT2609297	hsa-miR-421	CLIP-seq
MIRT2313053	hsa-miR-424	CLIP-seq
MIRT2609298	hsa-miR-4263	CLIP-seq
MIRT2609299	hsa-miR-4273	CLIP-seq
MIRT2609300	hsa-miR-4328	CLIP-seq
MIRT2313054	hsa-miR-433	CLIP-seq
MIRT2432476	hsa-miR-4429	CLIP-seq
MIRT2609301	hsa-miR-4450	CLIP-seq
MIRT2313055	hsa-miR-4484	CLIP-seq
MIRT2609302	hsa-miR-4495	CLIP-seq
MIRT2609304	hsa-miR-451b	CLIP-seq
MIRT2393555	hsa-miR-4640-3p	CLIP-seq
MIRT2609305	hsa-miR-4643	CLIP-seq
MIRT2609306	hsa-miR-466	CLIP-seq
MIRT2609307	hsa-miR-4677-5p	CLIP-seq
MIRT1296553	hsa-miR-4686	CLIP-seq
MIRT2609310	hsa-miR-4742-3p	CLIP-seq
MIRT2609311	hsa-miR-4777-3p	CLIP-seq
MIRT2609312	hsa-miR-4789-3p	CLIP-seq
MIRT2609314	hsa-miR-4799-5p	CLIP-seq
MIRT1296555	hsa-miR-485-3p	CLIP-seq
MIRT1296556	hsa-miR-487a	CLIP-seq
MIRT2609315	hsa-miR-491-3p	CLIP-seq
MIRT2609316	hsa-miR-494	CLIP-seq
MIRT2609317	hsa-miR-495	CLIP-seq
MIRT2313056	hsa-miR-497	CLIP-seq
MIRT2609318	hsa-miR-501-3p	CLIP-seq
MIRT2609319	hsa-miR-502-3p	CLIP-seq
MIRT2609321	hsa-miR-505	CLIP-seq
MIRT2609322	hsa-miR-513a-3p	CLIP-seq
MIRT2609324	hsa-miR-526b	CLIP-seq
MIRT2313058	hsa-miR-548an	CLIP-seq
MIRT2609330	hsa-miR-548c-3p	CLIP-seq
MIRT2609332	hsa-miR-548l	CLIP-seq
MIRT2609333	hsa-miR-548n	CLIP-seq
MIRT2432477	hsa-miR-549	CLIP-seq
MIRT2609336	hsa-miR-567	CLIP-seq
MIRT2609337	hsa-miR-576-5p	CLIP-seq
MIRT2609338	hsa-miR-582-5p	CLIP-seq
MIRT2609340	hsa-miR-590-3p	CLIP-seq
MIRT2609341	hsa-miR-619	CLIP-seq

Show/Hide all(16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000381	Process	Regulation of alternative mRNA splicing, via spliceosome	IBA	21873635
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IDA	25578728, 30824372
GO:0003723	Function	RNA binding	IMP	25189701
GO:0003727	Function	Single-stranded RNA binding	IBA	21873635
GO:0005515	Function	Protein binding	IPI	16263084, 25578728, 27871484, 27905398, 30824372, 32296183
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	IDA	21855801
GO:0005654	Component	Nucleoplasm	IDA	16263084
GO:0005730	Component	Nucleolus	IDA	21855801
GO:0016076	Process	SnRNA catabolic process	IMP	25852104
GO:0017069	Function	SnRNA binding	IDA	25852104
GO:0051321	Process	Meiotic cell cycle	IEA
GO:0071889	Function	14-3-3 protein binding	IDA	25189701
GO:0071889	Function	14-3-3 protein binding	IPI	25189701
GO:0097157	Function	Pre-mRNA intronic binding	IDA	25578728

MIM	HGNC	e!Ensembl
612413	9904	ENSG00000076053

Protein

UniProt ID

Q9Y580

Protein name

RNA-binding protein 7 (RNA-binding motif protein 7)

Protein function

RNA-binding subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation (PubMed:25189701, PubMed:25525152, Pu

PDB

2M8H , 5IQQ , 5LXR , 5LXY , 7S7B , 7S7C

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00076	RRM_1	12 → 81	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain

Sequence

MGAAAAEADRTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKDKDGKPKQFAFVNFKHE
VSVPYAMNLLNGIKLYGRPIKIQFRSGSSHAPQDVSLSYPQHHVGNSSPTSTSPSRYERT
MDNMTSSAQIIQRSFSSPENFQRQAVMNSALRQMSYGGKFGSSPLDQSGFSPSVQSHSHS
FNQSSSSQWRQGTPSSQRKVRMNSYPYLADRHYSREQRYTDHGSDHHYRGKRDDFFYEDR
NHDDWSHDYDNRRDSSRDGKWRSSRH

Sequence length

266

Interactions

View interactions

Associated diseases

Show/Hide Causal Diseases (1)

Causal
Disease name	Disease term	dbSNP ID	References
Lung carcinoma	Non-Small Cell Lung Carcinoma	rs1805076, rs121909071, rs121913530, rs112445441, rs121913529, rs121913535, rs121913297, rs121913279, rs104886003, rs397516975, rs11554290, rs121913364, rs121913351, rs121913369, rs121913355, rs121912470, rs121913273, rs121913281, rs121913348, rs727503093, rs121913353, rs397516890, rs397516896, rs121913378, rs397516897, rs397516977, rs397516978, rs397516979, rs397516980, rs397516981, rs397516982, rs121913240, rs17851045, rs397517086, rs121913428, rs397517094, rs397517098, rs397517106, rs121913465, rs397517108, rs397517111, rs397517112, rs397517114, rs397517116, rs1554350366, rs397517127, rs397517200, rs397517202, rs121913283, rs121913370, rs121913357, rs727503106, rs121913238, rs727503108, rs397517040, rs397516976, rs1555618025, rs1057519729, rs1584238193	15496427

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