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COX17 (cytochrome c oxidase copper chaperone COX17)
Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
10063
Gene nameGene Name - the full gene name approved by the HGNC.
Cytochrome c oxidase copper chaperone COX17
Gene symbolGene Symbol - the official gene symbol approved by the HGNC, which is a short abbreviated form of the gene name.
COX17
SynonymsGene synonyms aliases
-
ChromosomeChromosome number
3
Chromosome locationChromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3q13.33
SummarySummary of gene provided in NCBI Entrez Gene.
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochond
miRNAmiRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
miRTarBase ID miRNA Experiments Reference
MIRT045209 hsa-miR-186-5p CLASH 23622248
MIRT612014 hsa-miR-6782-3p HITS-CLIP 23824327
MIRT612013 hsa-miR-875-5p HITS-CLIP 23824327
MIRT612012 hsa-miR-1207-3p HITS-CLIP 23824327
MIRT612011 hsa-miR-4251 HITS-CLIP 23824327
Gene ontology (GO)Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
GO ID Ontology Definition Evidence Reference
GO:0005507 Function Copper ion binding TAS 9050918
GO:0005515 Function Protein binding IPI 16189514, 18458339, 19182799, 25416956, 29568061, 32296183, 32814053
GO:0005737 Component Cytoplasm IDA 19393246
GO:0005758 Component Mitochondrial intermembrane space IBA 21873635
GO:0005758 Component Mitochondrial intermembrane space IDA 19393246
Other IDsOther ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM
HGNC
e!Ensembl
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q14061
Protein name Cytochrome c oxidase copper chaperone
Protein function Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions
PDB 2L0Y , 2LGQ , 2RN9 , 2RNB
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05051 COX17
18 → 63
Cytochrome C oxidase copper chaperone (COX17)
 Family
Sequence
Sequence length 63
Interactions View interactions
PathwaysPathway information has different metabolic/signaling pathways associated with genes. Each record is hyperlinked to a complete information page which also includes links to the KEGG/Reactome pathway database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
 
KEGG
  
  Oxidative phosphorylation
Metabolic pathways
Thermogenesis 		 
Associated diseases
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Causal
Disease name Disease term dbSNP ID References
Lung cancer Malignant neoplasm of lung rs121913530, rs121913529, rs878855122, rs1057519784, rs770315135 23624903
Unknown
Disease name Disease term dbSNP ID References
Lung neoplasms Lung Neoplasms 23624903

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