# GeDiPNet Shared-Gene Disease Pairs -- generated 2026-10-10 08:32:17
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test (P(X>=k)), Benjamini-Hochberg FDR-corrected across all tested pairs. Corroborated Shared Genes: count of shared genes backed by >=2 distinct disease_gdp.main_source values combined across both diseases (e.g. GWAS-backed for one, ClinVar-backed for the other still counts); Shared Gene Names lists each gene's own source count in parentheses. Overlap Coefficient: shared genes / MIN(each disease's own total gene count) -- complements the Jaccard-based Similarity Score by showing how much of the SMALLER disease's entire known gene-set is covered by this pair, which Jaccard (dividing by the union) can understate. Shared Cluster: cluster id if both diseases fall in the same label-propagation cluster (scripts/build_disease_clusters.php), blank otherwise. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-10 03:00:13. Filters applied: disease name contains "short chain acyl-coa dehydrogenase deficiency" (5 matching pairs).
Disease A	Disease B	Shared Genes	Corroborated Shared Genes	Shared Gene Names	Similarity Score	Overlap Coefficient	P-value	FDR Q-value	Shared Cluster
Anorexia nervosa	short chain acyl-coa dehydrogenase deficiency	1	1	ACADS (2)	0.00397	1.00000	1.630e-2	1.793e-2	
Obsessive-compulsive disorder	short chain acyl-coa dehydrogenase deficiency	1	1	ACADS (2)	0.00426	1.00000	1.520e-2	1.679e-2	
Congestive heart failure	short chain acyl-coa dehydrogenase deficiency	1	1	ACADS (2)	0.00556	1.00000	1.162e-2	1.305e-2	
Cannabis abuse	short chain acyl-coa dehydrogenase deficiency	1	1	ACADS (2)	0.00855	1.00000	7.533e-3	8.832e-3	
Butyryl-coa dehydrogenase deficiency	short chain acyl-coa dehydrogenase deficiency	1	1	ACADS (3)	0.33333	1.00000	1.299e-4	3.931e-4