# GeDiPNet Shared-Gene Disease Pairs -- generated 2026-10-21 13:01:57 # Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test (P(X>=k)), Benjamini-Hochberg FDR-corrected across all tested pairs. Corroborated Shared Genes: count of shared genes backed by >=2 distinct disease_gdp.main_source values combined across both diseases (e.g. GWAS-backed for one, ClinVar-backed for the other still counts); Shared Gene Names lists each gene's own source count in parentheses. Overlap Coefficient: shared genes / MIN(each disease's own total gene count) -- complements the Jaccard-based Similarity Score by showing how much of the SMALLER disease's entire known gene-set is covered by this pair, which Jaccard (dividing by the union) can understate. Shared Cluster: cluster id if both diseases fall in the same label-propagation cluster (scripts/build_disease_clusters.php), blank otherwise. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-21 12:58:11. Filters applied: disease name contains "Muscular dystrophy-dystroglycanopathy" (89 matching pairs). Disease A Disease B Shared Genes Corroborated Shared Genes Shared Gene Names Similarity Score Overlap Coefficient P-value FDR Q-value Shared Cluster Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a13 Rheumatoid arthritis 1 1 B3GNT2 (4) 0.00151 0.50000 8.354e-2 8.451e-2 Breast neoplasms Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a13 1 1 B4GAT1 (3) 0.00189 0.50000 6.677e-2 6.809e-2 Gout Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b15 1 1 DPM3 (2) 0.00122 1.00000 5.282e-2 5.432e-2 Cardiomyopathy Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b15 1 1 DPM3 (2) 0.00394 1.00000 1.634e-2 1.773e-2 Graves disease Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a13 1 1 B3GNT2 (3) 0.00980 0.50000 1.287e-2 1.420e-2 Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b15 Myopathy 1 1 DPM3 (2) 0.00826 1.00000 7.748e-3 8.873e-3 140 Congenital disorder of glycosylation Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b15 1 1 DPM3 (5) 0.00990 1.00000 6.457e-3 7.556e-3 Limb-girdle muscular dystrophy Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a8 1 0 POMGNT2 (1) 0.02326 1.00000 2.712e-3 3.483e-3 Limb-girdle muscular dystrophy Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a9 1 1 DAG1 (3) 0.02326 1.00000 2.712e-3 3.483e-3 Limb-girdle muscular dystrophy Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b15 1 0 DPM3 (1) 0.02326 1.00000 2.712e-3 3.483e-3 140 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a13 Walker-warburg syndrome 1 1 B4GAT1 (5) 0.05556 0.50000 2.065e-3 2.786e-3 366 Muscle eye brain disease Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a13 1 1 B4GAT1 (3) 0.05882 0.50000 1.936e-3 2.647e-3 366 Congenital muscular dystrophy Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a12 1 1 POMK (3) 0.04167 1.00000 1.485e-3 2.122e-3 Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b3 Walker-warburg syndrome 1 1 POMGNT1 (4) 0.05882 1.00000 1.033e-3 1.574e-3 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a4 Walker-warburg syndrome 1 1 FKTN (4) 0.05882 1.00000 1.033e-3 1.574e-3 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a2 Walker-warburg syndrome 1 1 POMT2 (4) 0.05882 1.00000 1.033e-3 1.574e-3 Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b6 Walker-warburg syndrome 1 1 LARGE1 (4) 0.05882 1.00000 1.033e-3 1.574e-3 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a12 Walker-warburg syndrome 1 1 POMK (4) 0.05882 1.00000 1.033e-3 1.574e-3 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a10 Walker-warburg syndrome 1 1 RXYLT1 (4) 0.05882 1.00000 1.033e-3 1.574e-3 Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b2 Walker-warburg syndrome 1 1 POMT2 (4) 0.05882 1.00000 1.033e-3 1.574e-3 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a6 Walker-warburg syndrome 1 1 LARGE1 (4) 0.05882 1.00000 1.033e-3 1.574e-3 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a9 Walker-warburg syndrome 1 1 DAG1 (4) 0.05882 1.00000 1.033e-3 1.574e-3 Muscular dystrophy-dystroglycanopathy (congenital without impaired intellectual development), type b4 Walker-warburg syndrome 1 1 FKTN (4) 0.05882 1.00000 1.033e-3 1.574e-3 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a8 Walker-warburg syndrome 1 1 POMGNT2 (4) 0.05882 1.00000 1.033e-3 1.574e-3 Muscle eye brain disease Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a9 1 1 DAG1 (3) 0.06250 1.00000 9.685e-4 1.497e-3 Muscle eye brain disease Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a8 1 1 POMGNT2 (2) 0.06250 1.00000 9.685e-4 1.497e-3 Muscle eye brain disease Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a6 1 1 LARGE1 (3) 0.06250 1.00000 9.685e-4 1.497e-3 Muscle eye brain disease Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a2 1 1 POMT2 (4) 0.06250 1.00000 9.685e-4 1.497e-3 Muscle eye brain disease Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a4 1 1 FKTN (4) 0.06250 1.00000 9.685e-4 1.497e-3 Muscle eye brain disease Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b3 1 1 POMGNT1 (4) 0.06250 1.00000 9.685e-4 1.497e-3 Muscle eye brain disease Muscular dystrophy-dystroglycanopathy (congenital without impaired intellectual development), type b4 1 1 FKTN (4) 0.06250 1.00000 9.685e-4 1.497e-3 Muscle eye brain disease Muscular dystrophy-dystroglycanopathy (congenital with or without impaired intellectual development), type b5 1 1 FKRP (4) 0.06250 1.00000 9.685e-4 1.497e-3 Muscle eye brain disease Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b6 1 1 LARGE1 (3) 0.06250 1.00000 9.685e-4 1.497e-3 Muscle eye brain disease Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a10 1 1 RXYLT1 (3) 0.06250 1.00000 9.685e-4 1.497e-3 Muscle eye brain disease Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b2 1 1 POMT2 (4) 0.06250 1.00000 9.685e-4 1.497e-3 Muscle eye brain disease Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a12 1 1 POMK (2) 0.06250 1.00000 9.685e-4 1.497e-3 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a1 Sensory neuropathy 1 1 POMT1 (2) 0.06667 1.00000 9.039e-4 1.411e-3 Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b1 Sensory neuropathy 1 1 POMT1 (2) 0.06667 1.00000 9.039e-4 1.411e-3 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a1 Pyridoxine dependent epilepsy 1 1 POMT1 (2) 0.11111 1.00000 5.165e-4 9.126e-4 Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b1 Pyridoxine dependent epilepsy 1 1 POMT1 (2) 0.11111 1.00000 5.165e-4 9.126e-4 Congenital muscular dystrophy due to dystroglycanopathy Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b3 1 1 POMGNT1 (2) 0.12500 1.00000 4.520e-4 8.264e-4 Congenital muscular dystrophy due to dystroglycanopathy Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b6 1 1 LARGE1 (2) 0.12500 1.00000 4.520e-4 8.264e-4 Congenital muscular dystrophy due to dystroglycanopathy Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a6 1 1 LARGE1 (2) 0.12500 1.00000 4.520e-4 8.264e-4 Congenital muscular dystrophy due to dystroglycanopathy Muscular dystrophy-dystroglycanopathy (congenital with or without impaired intellectual development), type b5 1 1 FKRP (2) 0.12500 1.00000 4.520e-4 8.264e-4 Kenny-caffey syndrome Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a11 1 1 B3GALNT2 (3) 0.20000 0.50000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a11 1 1 B3GALNT2 (2) 0.20000 0.50000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a Myopathy caused by variation in POMT1 1 1 POMT1 (2) 0.14286 1.00000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a Myopathy caused by variation in POMT2 1 1 POMT2 (2) 0.14286 1.00000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a Myopathy caused by variation in POMGNT1 1 1 POMGNT1 (2) 0.14286 1.00000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a Myopathy caused by variation in FKTN 1 1 FKTN (2) 0.14286 1.00000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a Muscular dystrophy-dystroglycanopathy (congenital without impaired intellectual development), type b4 1 0 FKTN (1) 0.14286 1.00000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b1 1 0 POMT1 (1) 0.14286 1.00000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b3 1 0 POMGNT1 (1) 0.14286 1.00000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b2 1 0 POMT2 (1) 0.14286 1.00000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a9 1 0 DAG1 (1) 0.14286 1.00000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a1 1 0 POMT1 (1) 0.14286 1.00000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a Neuromuscular disease caused by qualitative or quantitative defects of alpha-dystroglycan 1 1 DAG1 (2) 0.14286 1.00000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a4 1 0 FKTN (1) 0.14286 1.00000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a12 1 0 POMK (1) 0.14286 1.00000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a2 1 0 POMT2 (1) 0.14286 1.00000 3.874e-4 7.329e-4 Muscular dystrophy-dystroglycanopathy (congenital with or without impaired intellectual development), type b5 Paresthesia 1 1 FKRP (2) 0.16667 1.00000 3.228e-4 6.413e-4 Muscular dystrophy-dystroglycanopathy Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b6 1 1 LARGE1 (2) 0.25000 1.00000 1.937e-4 4.415e-4 Muscular dystrophy-dystroglycanopathy Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a6 1 1 LARGE1 (2) 0.25000 1.00000 1.937e-4 4.415e-4 Muscular dystrophy-dystroglycanopathy Myopathy caused by variation in GMPPB 1 1 GMPPB (2) 0.25000 1.00000 1.937e-4 4.415e-4 Congenital muscular dystrophies Muscular dystrophy-dystroglycanopathy 1 0 B3GALNT2 (1) 0.25000 1.00000 1.937e-4 4.415e-4 Cobblestone lissencephaly Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a10 1 0 RXYLT1 (1) 0.25000 1.00000 1.937e-4 4.415e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a11 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a12 1 0 POMK (1) 0.33333 1.00000 1.291e-4 3.269e-4 Congenital muscular dystrophies Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a11 1 1 B3GALNT2 (2) 0.33333 1.00000 1.291e-4 3.269e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a1 Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b1 1 0 POMT1 (1) 0.50000 1.00000 6.457e-5 1.985e-4 Muscular dystrophy-dystroglycanopathy (congenital with or without impaired intellectual development), type b5 Myopathy caused by variation in FKRP 1 1 FKRP (2) 0.50000 1.00000 6.457e-5 1.985e-4 Muscular dystrophy-dystroglycanopathy (congenital without impaired intellectual development), type b4 Myopathy caused by variation in FKTN 1 1 FKTN (2) 0.50000 1.00000 6.457e-5 1.985e-4 Congenital alpha-dystroglycanopathy with brain and eye anomalies Muscular dystrophy-dystroglycanopathy (congenital with or without impaired intellectual development), type b5 1 0 FKRP (1) 0.50000 1.00000 6.457e-5 1.985e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a4 Myopathy caused by variation in FKTN 1 1 FKTN (2) 0.50000 1.00000 6.457e-5 1.985e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a8 Walker warberg spectrum disorder 1 0 POMGNT2 (1) 0.50000 1.00000 6.457e-5 1.985e-4 Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b1 Myopathy caused by variation in POMT1 1 1 POMT1 (2) 0.50000 1.00000 6.457e-5 1.985e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a8 Myopathy caused by variation in POMGNT2 1 1 POMGNT2 (2) 0.50000 1.00000 6.457e-5 1.985e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a6 Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b6 1 0 LARGE1 (1) 0.50000 1.00000 6.457e-5 1.985e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a4 Muscular dystrophy-dystroglycanopathy (congenital without impaired intellectual development), type b4 1 0 FKTN (1) 0.50000 1.00000 6.457e-5 1.985e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a1 Myopathy caused by variation in POMT1 1 1 POMT1 (2) 0.50000 1.00000 6.457e-5 1.985e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a2 Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b2 1 0 POMT2 (1) 0.50000 1.00000 6.457e-5 1.985e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a2 Myopathy caused by variation in POMT2 1 1 POMT2 (2) 0.50000 1.00000 6.457e-5 1.985e-4 Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b2 Myopathy caused by variation in POMT2 1 1 POMT2 (2) 0.50000 1.00000 6.457e-5 1.985e-4 Muscular dystrophy-dystroglycanopathy (congenital with impaired intellectual development), type b3 Myopathy caused by variation in POMGNT1 1 1 POMGNT1 (2) 0.50000 1.00000 6.457e-5 1.985e-4 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a9 Neuromuscular disease caused by qualitative or quantitative defects of alpha-dystroglycan 1 1 DAG1 (2) 0.50000 1.00000 6.457e-5 1.985e-4 Muscle eye brain disease Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a11 2 2 B3GALNT2 (5), POMK (2) 0.12500 1.00000 8.755e-7 5.368e-6 Congenital muscular dystrophy due to dystroglycanopathy Muscular dystrophy-dystroglycanopathy 3 3 GMPPB (2), LARGE1 (3), B3GALNT2 (2) 0.37500 1.00000 5.654e-11 5.397e-10 Congenital muscular dystrophy Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a 5 5 POMT1 (4), POMT2 (4), POMGNT1 (4), FKTN (4), POMK (3) 0.20000 0.83333 2.718e-14 3.183e-13 366 Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a Walker-warburg syndrome 6 6 DAG1 (4), POMT1 (4), POMT2 (4), POMGNT1 (4), FKTN (4), POMK (4) 0.35294 1.00000 4.181e-19 5.928e-18 366 Muscle eye brain disease Muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type a 6 6 DAG1 (3), POMT1 (4), POMT2 (4), POMGNT1 (4), FKTN (4), POMK (2) 0.37500 1.00000 2.613e-19 3.724e-18 366