# GeDiPNet Shared-Gene Disease Pairs -- generated 2026-10-20 03:59:19
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test (P(X>=k)), Benjamini-Hochberg FDR-corrected across all tested pairs. Corroborated Shared Genes: count of shared genes backed by >=2 distinct disease_gdp.main_source values combined across both diseases (e.g. GWAS-backed for one, ClinVar-backed for the other still counts); Shared Gene Names lists each gene's own source count in parentheses. Overlap Coefficient: shared genes / MIN(each disease's own total gene count) -- complements the Jaccard-based Similarity Score by showing how much of the SMALLER disease's entire known gene-set is covered by this pair, which Jaccard (dividing by the union) can understate. Shared Cluster: cluster id if both diseases fall in the same label-propagation cluster (scripts/build_disease_clusters.php), blank otherwise. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-20 03:00:20. Filters applied: disease name contains "Epileptic encephalopathy, early infantile, 62" (5 matching pairs).
Disease A	Disease B	Shared Genes	Corroborated Shared Genes	Shared Gene Names	Similarity Score	Overlap Coefficient	P-value	FDR Q-value	Shared Cluster
Epileptic encephalopathy, early infantile, 62	Genetic developmental and epileptic encephalopathy	1	1	SCN3A (2)	0.02703	1.00000	2.324e-3	3.054e-3	
Epileptic encephalopathy, early infantile, 62	Polymicrogyria	1	1	SCN3A (2)	0.03333	1.00000	1.872e-3	2.572e-3	
Epileptic encephalopathy, early infantile, 62	Perisylvian syndrome	1	1	SCN3A (2)	0.09091	1.00000	6.457e-4	1.087e-3	
Epileptic encephalopathy, early infantile, 62	Familial focal epilepsy with variable foci	1	1	SCN3A (5)	0.11111	1.00000	5.165e-4	9.125e-4	
Complex partial epilepsy	Epileptic encephalopathy, early infantile, 62	1	1	SCN3A (3)	0.50000	1.00000	6.457e-5	1.985e-4