# GeDiPNet Shared-Gene Disease Pairs -- generated 2026-10-13 23:19:05
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test (P(X>=k)), Benjamini-Hochberg FDR-corrected across all tested pairs. Corroborated Shared Genes: count of shared genes backed by >=2 distinct disease_gdp.main_source values combined across both diseases (e.g. GWAS-backed for one, ClinVar-backed for the other still counts); Shared Gene Names lists each gene's own source count in parentheses. Overlap Coefficient: shared genes / MIN(each disease's own total gene count) -- complements the Jaccard-based Similarity Score by showing how much of the SMALLER disease's entire known gene-set is covered by this pair, which Jaccard (dividing by the union) can understate. Shared Cluster: cluster id if both diseases fall in the same label-propagation cluster (scripts/build_disease_clusters.php), blank otherwise. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-14 03:00:13. Filters applied: disease name contains "Anterior maxillary protrusion-strabismus-intellectual disability syndrome" (5 matching pairs).
Disease A	Disease B	Shared Genes	Corroborated Shared Genes	Shared Gene Names	Similarity Score	Overlap Coefficient	P-value	FDR Q-value	Shared Cluster
Anterior maxillary protrusion-strabismus-intellectual disability syndrome	Basal cell carcinoma	1	1	SOBP (3)	0.00305	1.00000	2.124e-2	2.305e-2	
Anterior maxillary protrusion-strabismus-intellectual disability syndrome	Psychotic disorders	1	1	SOBP (2)	0.00794	1.00000	8.118e-3	9.424e-3	
Anterior maxillary protrusion-strabismus-intellectual disability syndrome	Non-organic psychosis	1	1	SOBP (2)	0.01429	1.00000	4.481e-3	5.604e-3	
Anterior maxillary protrusion-strabismus-intellectual disability syndrome	syndromic intellectual disability	1	1	SOBP (3)	0.02703	1.00000	2.338e-3	3.243e-3	
Anterior maxillary protrusion-strabismus-intellectual disability syndrome	Intellectual disability, anterior maxillary protrusion, and strabismus	1	1	SOBP (3)	0.50000	1.00000	6.494e-5	2.331e-4