# GeDiPNet Shared-Gene Disease Pairs -- generated 2026-10-11 06:03:40
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test (P(X>=k)), Benjamini-Hochberg FDR-corrected across all tested pairs. Corroborated Shared Genes: count of shared genes backed by >=2 distinct disease_gdp.main_source values combined across both diseases (e.g. GWAS-backed for one, ClinVar-backed for the other still counts); Shared Gene Names lists each gene's own source count in parentheses. Overlap Coefficient: shared genes / MIN(each disease's own total gene count) -- complements the Jaccard-based Similarity Score by showing how much of the SMALLER disease's entire known gene-set is covered by this pair, which Jaccard (dividing by the union) can understate. Shared Cluster: cluster id if both diseases fall in the same label-propagation cluster (scripts/build_disease_clusters.php), blank otherwise. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-11 03:00:14. Filters applied: disease name contains "hao-fountain syndrome" (5 matching pairs).
Disease A	Disease B	Shared Genes	Corroborated Shared Genes	Shared Gene Names	Similarity Score	Overlap Coefficient	P-value	FDR Q-value	Shared Cluster
16p13.2 microdeletion syndrome	hao-fountain syndrome	1	1	USP7 (2)	0.50000	1.00000	6.494e-5	2.331e-4	
Diabetic maculopathy	hao-fountain syndrome	1	1	USP7 (2)	0.10000	1.00000	5.845e-4	1.156e-3	
hao-fountain syndrome	Urinary bladder neoplasms	1	1	USP7 (2)	0.00699	1.00000	9.222e-3	1.053e-2	
hao-fountain syndrome	Ovarian serous carcinoma	1	1	USP7 (2)	0.00369	1.00000	1.753e-2	1.921e-2	
Androgenetic alopecia	hao-fountain syndrome	1	1	USP7 (2)	0.00244	1.00000	2.650e-2	2.826e-2