# GeDiPNet Shared-Gene Disease Pairs -- generated 2026-10-10 17:48:41
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test (P(X>=k)), Benjamini-Hochberg FDR-corrected across all tested pairs. Corroborated Shared Genes: count of shared genes backed by >=2 distinct disease_gdp.main_source values combined across both diseases (e.g. GWAS-backed for one, ClinVar-backed for the other still counts); Shared Gene Names lists each gene's own source count in parentheses. Overlap Coefficient: shared genes / MIN(each disease's own total gene count) -- complements the Jaccard-based Similarity Score by showing how much of the SMALLER disease's entire known gene-set is covered by this pair, which Jaccard (dividing by the union) can understate. Shared Cluster: cluster id if both diseases fall in the same label-propagation cluster (scripts/build_disease_clusters.php), blank otherwise. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-10 03:00:13. Filters applied: disease name contains "dilated cardiomyopathy 1C" (10 matching pairs).
Disease A	Disease B	Shared Genes	Corroborated Shared Genes	Shared Gene Names	Similarity Score	Overlap Coefficient	P-value	FDR Q-value	Shared Cluster
cardiomyopathy, dilated, 2l	dilated cardiomyopathy 1C	1	0	LDB3 (1)	0.50000	1.00000	6.494e-5	2.331e-4	
dilated cardiomyopathy 1C	Distal muscular dystrophy	1	1	LDB3 (2)	0.12500	1.00000	4.546e-4	9.726e-4	
dilated cardiomyopathy 1C	Myofibrillar myopathy	1	1	LDB3 (4)	0.07692	1.00000	7.793e-4	1.405e-3	
Arrhythmogenic right ventricular dysplasia	dilated cardiomyopathy 1C	1	1	LDB3 (2)	0.06667	1.00000	9.092e-4	1.576e-3	
dilated cardiomyopathy 1C	Left ventricular noncompaction cardiomyopathy	1	1	LDB3 (2)	0.02564	1.00000	2.468e-3	3.371e-3	
dilated cardiomyopathy 1CC	Left ventricular noncompaction cardiomyopathy	1	1	NEXN (2)	0.02564	1.00000	2.468e-3	3.371e-3	4
Arrhythmogenic right ventricular cardiomyopathy	dilated cardiomyopathy 1CC	1	1	NEXN (2)	0.01887	1.00000	3.377e-3	4.374e-3	4
dilated cardiomyopathy 1CC	Left ventricular disease	1	1	NEXN (2)	0.01493	1.00000	4.286e-3	5.383e-3	4
dilated cardiomyopathy 1CC	Long qt syndrome	1	1	NEXN (2)	0.00971	1.00000	6.624e-3	7.889e-3	4
Cardiomyopathy	dilated cardiomyopathy 1CC	1	1	NEXN (4)	0.00408	1.00000	1.585e-2	1.746e-2	
