# GeDiPNet Shared-Gene Disease Pairs -- generated 2026-10-09 17:42:56
# Similarity: Jaccard index on shared curated genes (disease_gdp). Significance: upper-tail hypergeometric test (P(X>=k)), Benjamini-Hochberg FDR-corrected across all tested pairs. Corroborated Shared Genes: count of shared genes backed by >=2 distinct disease_gdp.main_source values combined across both diseases (e.g. GWAS-backed for one, ClinVar-backed for the other still counts); Shared Gene Names lists each gene's own source count in parentheses. Overlap Coefficient: shared genes / MIN(each disease's own total gene count) -- complements the Jaccard-based Similarity Score by showing how much of the SMALLER disease's entire known gene-set is covered by this pair, which Jaccard (dividing by the union) can understate. Shared Cluster: cluster id if both diseases fall in the same label-propagation cluster (scripts/build_disease_clusters.php), blank otherwise. See scripts/build_related.php on gedipnet.bicnirrh.res.in. Data as of: 2026-10-09 03:00:13. Filters applied: disease name contains "Sensorineural deafness with renal dysfunction" (5 matching pairs).
Disease A	Disease B	Shared Genes	Corroborated Shared Genes	Shared Gene Names	Similarity Score	Overlap Coefficient	P-value	FDR Q-value	Shared Cluster
Bartter syndrome	Sensorineural deafness with renal dysfunction	1	1	BSND (6)	0.10000	1.00000	5.845e-4	1.156e-3	
Seasonal allergic rhinitis	Sensorineural deafness with renal dysfunction	1	1	BSND (2)	0.00990	1.00000	6.494e-3	7.748e-3	
Isolated sensorineural deafness	Sensorineural deafness with renal dysfunction	1	0	BSND (1)	0.00833	1.00000	7.728e-3	9.013e-3	
Deafness	Sensorineural deafness with renal dysfunction	1	0	BSND (1)	0.00578	1.00000	1.117e-2	1.256e-2	
Diabetic neuropathy	Sensorineural deafness with renal dysfunction	1	1	BSND (2)	0.00426	1.00000	1.520e-2	1.678e-2